Anita Roy lab@IIT Delhi
LightNews LightNews
anitaroylab.bsky.social
Anita Roy lab@IIT Delhi
@anitaroylab.bsky.social
1 followers 20 following 5 posts
Looking at haematopoietic malignancies through microscopy - cytoskeletal regulation, thrombopoietin receptor, calreticulin, mTOR, megakaryopoiesis, MPN, B-ALL
Posts Replies Media Videos
anitaroylab.bsky.social
Check out our article on lysosome-autophagosome mediated secretion of thrombopoietin receptor in MPN #Membranetrafficking #MPN #lysosomes
www.nature.com/articles/s41...
Autophagosome-lysosome mediated secretion of the thrombopoietin receptor is modulated by distinct driver mutations of myeloproliferative neoplasm - Leukemia
Leukemia - Autophagosome-lysosome mediated secretion of the thrombopoietin receptor is modulated by distinct driver mutations of myeloproliferative neoplasm
www.nature.com
February 8, 2026 at 6:24 PM
anitaroylab.bsky.social
What does zebrafish thrombopoietin receptor teach us - a tale of two pronged signaling through Jak and mapk...
www.facebook.com/100066694747...
DBT - National Institute of Biomedical Genomics
Thrombopoietin receptor signalling permits the thrombocyte lineage development in human, mice as well as zebrafish. While the sequence, structure, signalling, and function of TpoR is well-conserved...
www.facebook.com
February 8, 2026 at 5:32 PM
anitaroylab.bsky.social
Another report on lenalidomide therapy induced ALL - confirms clonal evolution of the secondary malignancy just as we had predicted in 2024!
www.nature.com/articles/s41...
www.jbc.org/article/S002...
Evolution of clonal hematopoiesis on and off lenalidomide maintenance for multiple myeloma - Leukemia
Leukemia - Evolution of clonal hematopoiesis on and off lenalidomide maintenance for multiple myeloma
www.nature.com
February 8, 2026 at 5:10 PM
anitaroylab.bsky.social
Latest research from our lab....Thrombopoietin receptor traffic is regulated by non muscle myosin IIA
bsky.app/profile/jcel...
jcellsci.bsky.social Journal of Cell Science @jcellsci.bsky.social · Jan 7
Saurabh Shrivastva, Anita Roy and colleagues find that non-muscle myosin IIA and IIB differentially affect the traffic and signalling of the thrombopoietin receptor.
journals.biologists.com/jcs/article/...
Figure showing NMIIA affects anterograde traffic of TpoR–GFP-containing vesicles.
February 8, 2026 at 4:04 PM
anitaroylab.bsky.social
Research from our lab shows Type I calreticulin mutations deregulate mTORC2
rdcu.be/e2WO9
Differential regulation of mTORC2 signalling by type I and type II calreticulin (CALR) driver mutations of myeloproliferative neoplasm
rdcu.be
February 8, 2026 at 3:56 PM