Targeting this switch could offer new ways to modulate redox balance and iron metabolism in cancer.
Targeting this switch could offer new ways to modulate redox balance and iron metabolism in cancer.
But we found the opposite can also happen, when HMOX1 is inactive, heme accumulates and induces ferritin upregulation, buffering free iron and protecting cells from ferroptosis
But we found the opposite can also happen, when HMOX1 is inactive, heme accumulates and induces ferritin upregulation, buffering free iron and protecting cells from ferroptosis