Andy Chan 🇭🇰🇦🇺
@andysonchan.bsky.social
Fascinated by the mysteries of life, especially how tissue regenerates. Currently as postdoc in the Dominic Grün lab and SFB1425, exploring the decision between cardiac regeneration and fibrosis in mammals using single-cell and spatial transcriptomics.
We also built an Shinyapp interface that allows everyone to access our single cell and spatial datasets easily:
www.wuesi.medizin.uni-wuerzburg.de/cardiac_spat...
We envision our datasets will serve as a resource will provide insights for the cardiac and regeneration/fibrosis fields in the future!
www.wuesi.medizin.uni-wuerzburg.de/cardiac_spat...
We envision our datasets will serve as a resource will provide insights for the cardiac and regeneration/fibrosis fields in the future!
www.wuesi.medizin.uni-wuerzburg.de
November 3, 2025 at 11:41 AM
We also built an Shinyapp interface that allows everyone to access our single cell and spatial datasets easily:
www.wuesi.medizin.uni-wuerzburg.de/cardiac_spat...
We envision our datasets will serve as a resource will provide insights for the cardiac and regeneration/fibrosis fields in the future!
www.wuesi.medizin.uni-wuerzburg.de/cardiac_spat...
We envision our datasets will serve as a resource will provide insights for the cardiac and regeneration/fibrosis fields in the future!
Huge thanks to my PI Dominic @dominicgrun.bsky.social , my friends/colleagues in the lab, and all my collaborators who shared their efforts and dedication over these years!! This 5 year-journey wouldn’t have been successful
without you all! 🙏
Link of the paper:
www.nature.com/articles/s44...
without you all! 🙏
Link of the paper:
www.nature.com/articles/s44...
Spatiotemporal dynamics of the cardioimmune niche during lesion repair - Nature Cardiovascular Research
Chan et al. generate a high-resolution spatiotemporal atlas of healing hearts and reveal cellular networks of lesion repair, including macrophage–fibroblast interactions that control late-stage fibros...
www.nature.com
November 3, 2025 at 11:36 AM
Huge thanks to my PI Dominic @dominicgrun.bsky.social , my friends/colleagues in the lab, and all my collaborators who shared their efforts and dedication over these years!! This 5 year-journey wouldn’t have been successful
without you all! 🙏
Link of the paper:
www.nature.com/articles/s44...
without you all! 🙏
Link of the paper:
www.nature.com/articles/s44...
We built a single-cell & spatial transcriptomic atlas revealing how immune, fibroblasts, and cardiomyocytes coordinate during heart tissue repair, uncovering key crosstalk mechanisms that fine-tune fibrosis, and discovering a rare regenerative mechanism, existing in the adult fibrotic hearts.
November 3, 2025 at 11:31 AM
We built a single-cell & spatial transcriptomic atlas revealing how immune, fibroblasts, and cardiomyocytes coordinate during heart tissue repair, uncovering key crosstalk mechanisms that fine-tune fibrosis, and discovering a rare regenerative mechanism, existing in the adult fibrotic hearts.
Huge thanks to my PI Dominic @dominicgrun.bsky.social , my friends/colleagues in the lab, and all my collaborators who shared their efforts and dedication over these years!! This 5 year-journey wouldn’t have been successful
without you all! 🙏
without you all! 🙏
November 3, 2025 at 11:19 AM
Huge thanks to my PI Dominic @dominicgrun.bsky.social , my friends/colleagues in the lab, and all my collaborators who shared their efforts and dedication over these years!! This 5 year-journey wouldn’t have been successful
without you all! 🙏
without you all! 🙏
We built a single-cell & spatial transcriptomic atlas revealing how immune, fibroblasts, and cardiomyocytes coordinate during heart tissue repair, uncovering key crosstalk mechanisms that fine-tune fibrosis, and discovering a rare regenerative mechanism, existing in the adult fibrotic hearts.
November 3, 2025 at 11:16 AM
We built a single-cell & spatial transcriptomic atlas revealing how immune, fibroblasts, and cardiomyocytes coordinate during heart tissue repair, uncovering key crosstalk mechanisms that fine-tune fibrosis, and discovering a rare regenerative mechanism, existing in the adult fibrotic hearts.
Thanks Dominic, for all the support and guidance throughout these years ;) I learnt a lot in this journey!
November 3, 2025 at 11:10 AM
Thanks Dominic, for all the support and guidance throughout these years ;) I learnt a lot in this journey!