@andrologyj.bsky.social
The OR helps regulate sperm capacitation, the process that prepares sperm to fertilize the egg. Blocking or activating this receptor changes calcium levels and membrane dynamics—classic signs of capacitation.
📖 Read the study: doi.org/10.1111/andr...
📖 Read the study: doi.org/10.1111/andr...
The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation
Background The oxytocin receptor (OR) is a G-protein-coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, ...
doi.org
November 14, 2025 at 1:13 AM
The OR helps regulate sperm capacitation, the process that prepares sperm to fertilize the egg. Blocking or activating this receptor changes calcium levels and membrane dynamics—classic signs of capacitation.
📖 Read the study: doi.org/10.1111/andr...
📖 Read the study: doi.org/10.1111/andr...
🔗 Explore the full study: doi.org/10.1111/andr...
📸 Image used for illustrative purposes only. Credit: @isensusa Not affiliated with the study.
📸 Image used for illustrative purposes only. Credit: @isensusa Not affiliated with the study.
Low testosterone levels in men at age 31 associates with future risk of prediabetes and type 2 diabetes: A birth cohort study
Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15-year f...
doi.org
October 30, 2025 at 10:24 PM
🔗 Explore the full study: doi.org/10.1111/andr...
📸 Image used for illustrative purposes only. Credit: @isensusa Not affiliated with the study.
📸 Image used for illustrative purposes only. Credit: @isensusa Not affiliated with the study.
👉 Read the full study: doi.org/10.1111/andr...
Comparative analysis of reproductive toxicity of polystyrene‐nanoplastics and polystyrene‐microplastics in rat Sertoli cells
Background Microplastic pollution increasingly affects human health. Polystyrene nanoparticles (PS-NPs) and microplastics (PS-MPs) may impair Sertoli cells (SCs), vital for male fertility. Objecti...
doi.org
September 30, 2025 at 5:55 PM
👉 Read the full study: doi.org/10.1111/andr...
🔍 Findings:
PS-MPs (8 µm) stay outside but trigger inflammation
PS-NPs (80 nm) slip inside cells, causing stronger oxidative stress and apoptosis
💡 Takeaway: As environmental plastics break down into ever-smaller particles, their hidden risks to male fertility become more severe.
PS-MPs (8 µm) stay outside but trigger inflammation
PS-NPs (80 nm) slip inside cells, causing stronger oxidative stress and apoptosis
💡 Takeaway: As environmental plastics break down into ever-smaller particles, their hidden risks to male fertility become more severe.
September 30, 2025 at 5:55 PM
🔍 Findings:
PS-MPs (8 µm) stay outside but trigger inflammation
PS-NPs (80 nm) slip inside cells, causing stronger oxidative stress and apoptosis
💡 Takeaway: As environmental plastics break down into ever-smaller particles, their hidden risks to male fertility become more severe.
PS-MPs (8 µm) stay outside but trigger inflammation
PS-NPs (80 nm) slip inside cells, causing stronger oxidative stress and apoptosis
💡 Takeaway: As environmental plastics break down into ever-smaller particles, their hidden risks to male fertility become more severe.
This balance between glucose and lactate may be key to sperm preservation, handling, and fertility success.
👉 Read the full study in Andrology: doi.org/10.1111/andr...
👉 Read the full study in Andrology: doi.org/10.1111/andr...
Lactate inhibits glucose‐induced zigzag motility and enhances linear motility in bull spermatozoa by suppressing glycolysis
Background Energy metabolism and substrate balance are critical determinants of sperm motility and fertility. Linear motility is necessary for sperm forward movement, whereas hyperactivated motility...
doi.org
September 3, 2025 at 7:57 PM
This balance between glucose and lactate may be key to sperm preservation, handling, and fertility success.
👉 Read the full study in Andrology: doi.org/10.1111/andr...
👉 Read the full study in Andrology: doi.org/10.1111/andr...
⚡ The findings raise important questions about how everyday technologies may impact reproductive biology.
👉 Read more: doi.org/10.1111/andr...
👉 Read more: doi.org/10.1111/andr...
Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats
Background The widespread usage of millimeter waves (MMW) in different spheres of the public domain necessitates to have a better understanding of any possible health impacts caused by them. The lat...
doi.org
August 28, 2025 at 9:03 PM
⚡ The findings raise important questions about how everyday technologies may impact reproductive biology.
👉 Read more: doi.org/10.1111/andr...
👉 Read more: doi.org/10.1111/andr...
The authors reconstruct Abraham’s family tree and explore whether these stories of late pregnancies and divine intervention could reflect a real familial pattern of infertility.
👉 Read more in Andrology: doi.org/10.1111/andr...
👉 Read more in Andrology: doi.org/10.1111/andr...
Genetics of infertility and “assisted fertilization” in the Bible: The case of Abraham and his family
Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th c...
doi.org
August 26, 2025 at 8:11 PM
The authors reconstruct Abraham’s family tree and explore whether these stories of late pregnancies and divine intervention could reflect a real familial pattern of infertility.
👉 Read more in Andrology: doi.org/10.1111/andr...
👉 Read more in Andrology: doi.org/10.1111/andr...
This research reveals striking differences not just between patients, but within different regions of the same tumour.
🔍 These insights could help uncover new strategies to slow tumour spread and improve patient outcomes.
👉 Read more: doi.org/10.1111/andr...
🔍 These insights could help uncover new strategies to slow tumour spread and improve patient outcomes.
👉 Read more: doi.org/10.1111/andr...
Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours
Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand...
doi.org
August 12, 2025 at 9:13 PM
This research reveals striking differences not just between patients, but within different regions of the same tumour.
🔍 These insights could help uncover new strategies to slow tumour spread and improve patient outcomes.
👉 Read more: doi.org/10.1111/andr...
🔍 These insights could help uncover new strategies to slow tumour spread and improve patient outcomes.
👉 Read more: doi.org/10.1111/andr...
These findings shed light on how poor sleep may contribute to ejaculatory dysfunction and point toward new therapeutic paths.
📖 Read more: doi.org/10.1111/andr...
📖 Read more: doi.org/10.1111/andr...
Brain structural and functional differences in anejaculation and sleep disorders: A functional magnetic resonance imaging‐based approach
Background and aims Sleep disorders (SDs) have been identified as an independent risk factor for ejaculatory dysfunctions; yet the neurophysiological mechanisms underlying the comorbidity between an...
doi.org
August 8, 2025 at 4:37 PM
These findings shed light on how poor sleep may contribute to ejaculatory dysfunction and point toward new therapeutic paths.
📖 Read more: doi.org/10.1111/andr...
📖 Read more: doi.org/10.1111/andr...
👉 Read the full study: doi.org/10.1111/andr...
A prospective study of semen quality and fecundability among North American couples planning pregnancy
Background
Few studies have prospectively evaluated semen quality (using the most up-to-date clinically relevant definitions) and fecundability (the per-cycle probability of conception).
Objective.....
doi.org
August 4, 2025 at 6:37 PM
👉 Read the full study: doi.org/10.1111/andr...
Using at-home semen tests, researchers found that lower sperm concentration, total count, and motile sperm count were all linked to reduced chances of conception per cycle.
🧬 Real-world data. Clinically relevant thresholds. Insightful takeaways for reproductive health.
🧬 Real-world data. Clinically relevant thresholds. Insightful takeaways for reproductive health.
August 4, 2025 at 6:37 PM
Using at-home semen tests, researchers found that lower sperm concentration, total count, and motile sperm count were all linked to reduced chances of conception per cycle.
🧬 Real-world data. Clinically relevant thresholds. Insightful takeaways for reproductive health.
🧬 Real-world data. Clinically relevant thresholds. Insightful takeaways for reproductive health.
🔬 A deep dive into the cellular mechanics behind hormone storage and release – with real implications for female reproductive longevity.
🔗 Read it in Andrology: doi.org/10.1111/andr...
🔗 Read it in Andrology: doi.org/10.1111/andr...
Gonadotropin storage and trafficking
Background Gonadotropins are synthesized in gonadotropes of the anterior pituitary, and they orchestrate reproductive function in vertebrates. LH and FSH share a common α-subunit that is non-covalen...
doi.org
August 1, 2025 at 4:39 PM
🔬 A deep dive into the cellular mechanics behind hormone storage and release – with real implications for female reproductive longevity.
🔗 Read it in Andrology: doi.org/10.1111/andr...
🔗 Read it in Andrology: doi.org/10.1111/andr...