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andrologyj.bsky.social
@andrologyj.bsky.social
❤️ The “love hormone” has a new target — sperm!

A new study in Andrology reveals that the oxytocin receptor (OR) in sperm may come from both spermatogenesis and epididymal maturation—and it’s not just along for the ride.
November 14, 2025 at 1:13 AM
Men with low testosterone at age 31 face a significantly higher risk of developing type 2 diabetes by midlife.

This 15-year birth cohort study shows the link persists after accounting for body weight and waist size, highlighting T as an independent metabolic risk factor.

Link in the comments.
October 30, 2025 at 10:24 PM
🐀 New in Andrology:

Lycium barbarum polysaccharides (LBP) restore spermatogenesis in aging rats by rebalancing calcium signaling.

LBP improved testicular structure, boosted spermatogonia, normalized sex hormone levels, and reduced oxidative stress and apoptosis.

Read more doi.org/10.1111/andr...
October 10, 2025 at 10:14 PM
Microplastics vs. Nanoplastics – A closer look at male fertility risks

New research compares polystyrene microplastics (PS-MPs) and nanoplastics (PS-NPs) in rat Sertoli cells, the key guardians of sperm development.
September 30, 2025 at 5:55 PM
⚡ How do sperm find the right “gear” for fertilization?

New research reveals that lactate shifts bull sperm from zigzag motility to straight-line movement by suppressing glycolysis and boosting oxidative metabolism. 🚀
September 3, 2025 at 7:57 PM
📡 Can prolonged exposure to 35.5 GHz millimeter waves, like those used in modern wireless tech, affect male fertility?

This study shows chronic exposure in rats led to oxidative stress, DNA damage, and impaired sperm quality, pointing to potential risks for testicular health.
August 28, 2025 at 9:03 PM
✨ Infertility in the Bible?

A new article looks at the Genetics of infertility and “assisted fertilization” in the Bible. It focuses on Abraham, Isaac and Jacob, whose wives all faced infertility.
August 26, 2025 at 8:11 PM
🧬 Why are some testicular tumours so hard to predict and treat?

New research uses spatial transcriptomics to map immune cell activity and TGFβ signaling in testicular germ cell tumours.
August 12, 2025 at 9:13 PM
💤⚡ Can sleepless nights harm sexual health?

New research in Andrology reveals how men with anejaculation, with and without sleep disorders, show striking brain differences on fMRI.
August 8, 2025 at 4:37 PM
📉 Does semen quality predict time to pregnancy?

A new prospective study published in Andrology examines semen parameters and fecundability in over 700 North American couples trying to conceive.
August 4, 2025 at 6:37 PM
🚨 LH and FSH may come from the same cell – but they follow very different paths.

This new review traces the evolution and trafficking of gonadotropins from primitive fish to mammals, revealing how molecular tweaks to FSH secretion can boost ovulation and ovarian health.
August 1, 2025 at 4:39 PM
New clues in the quest to predict male fertility in boars 🐖💡

Proteomic profiling of pig seminal extracellular vesicles reveals dozens of proteins linked to sperm function, embryo development, and implantation. These biomarkers could improve boar selection in AI programs.
July 14, 2025 at 4:26 PM
🧊 Freezing damages more than you think.

🔍 A new study in Andrology reveals how slow freezing reshapes sperm chromatin deep inside the nucleus.

This tool could be a game-changer for assessing sperm quality in fertility clinics.
July 9, 2025 at 5:29 PM
A new nationwide study published in Andrology reveals that the prevalence of hypospadias has significantly increased in China between 2010 and 2020.

🔍 Using data from over 11 million births, the research uncovers geographic and demographic disparities.
July 8, 2025 at 9:28 PM
Why don’t ED drugs work for everyone?
A new study published in Andrology uncovers two promising drug targets using genetic tools and single-cell technology—paving the way for next-gen erectile dysfunction treatments beyond Viagra.
👉 Find out more: doi.org/10.1111/andr...
June 23, 2025 at 6:14 PM
How does the immune system shape the maturing testis? 🧬🧪
A new study maps the immune cells of the testis before and after sexual maturation — revealing dynamic immune remodeling, rare B cells, and key crosstalk between immune and androgen-producing cells.
June 9, 2025 at 4:54 PM
Iron: essential for healthy testes — harmful when imbalanced. This new review explores how iron metabolism shapes spermatogenesis, testosterone production, and male fertility — and how both iron overload and deficiency can drive testicular dysfunction.

Read more here: doi.org/10.1111/andr...
June 6, 2025 at 4:16 PM
New research uncovers disrupted brain connectivity in individuals with hypoactive sexual desire disorder. The study identifies topological abnormalities in the left middle orbital frontal gyrus and amygdala, key regions for sexual motivation and emotional regulation.
May 27, 2025 at 3:42 PM
New in Andrology

A renowned Japanese research group specializing in testis-specific gene knockouts reports that simultaneous loss of RIBC1 and RIBC2 in mice leads to reduced sperm motility and smaller litter sizes—despite no structural defects visible under TEM.
April 23, 2025 at 9:05 PM
Can nanotechnology change the future of male fertility treatment?

As fertility challenges continue to rise—especially in aging populations—traditional treatments for testicular disorders often fall short due to side effects, invasiveness, and the tough-to-penetrate BTB.
April 16, 2025 at 8:06 PM
How can you use spatial transcriptomics to study spermatogenesis?

This review highlights how this technology is being used to study spermatogenesis by preserving tissue context—enabling researchers to explore spatial gene expression, cellular neighborhoods, and molecular changes in the testis.
April 11, 2025 at 8:04 PM
Diabetes may impair the epididymis, disrupting sperm maturation at a critical stage.

This systematic review, published in Andrology, links high glucose, oxidative stress, and hormonal imbalance to epididymal dysfunction in both humans and mice.

Read the fully study: doi.org/10.1111/andr...
April 10, 2025 at 10:29 PM
🧊 How well does sperm hold up in long-term storage?
New research published in Andrology shows that initial motility and vitality are key predictors of semen quality after years in cryostorage—even in patients with severely impaired semen parameters.
April 9, 2025 at 9:48 PM
Can we move toward a less invasive, more patient-friendly approach for diagnosing erectile dysfunction (ED)?
April 2, 2025 at 8:40 PM
Chronic opioid use is silently causing androgen deficiency in 20-80% of men, disrupting testosterone via GnRH suppression. It’s underrecognized by doctors, leaving many untreated. Testosterone therapy shows promise—boosting libido, body composition, and maybe even reducing pain.
March 7, 2025 at 5:22 PM