Andreas Wiest
@andreaswiest.bsky.social
LMU Munich
Chemical Biology of Protein Post-Translational Modifications
Chemoproteomics, Click Chemistry, Mass Spectrometry
Chemical Biology of Protein Post-Translational Modifications
Chemoproteomics, Click Chemistry, Mass Spectrometry
Reposted by Andreas Wiest
Great to see the new concept of protein PTMs functionalization published in @chemicalscience.rsc.org! The GlyTACs enable selective degradation of glycoproteins in living cells. Congratulation to Haoyu and Liu. Have a look on the full story here: pubs.rsc.org/en/Content/A... #chembio
Self-assembled PROTACs enable glycoproteins degradation in the living cells
We report here a two-component proteolysis targeting chimeras (PROTACs) strategy selectively targeting O-GalNAcylated and O-GlcNAcylated proteins for proteasomal degradation, which leads to severe tox...
pubs.rsc.org
April 10, 2025 at 4:34 AM
Great to see the new concept of protein PTMs functionalization published in @chemicalscience.rsc.org! The GlyTACs enable selective degradation of glycoproteins in living cells. Congratulation to Haoyu and Liu. Have a look on the full story here: pubs.rsc.org/en/Content/A... #chembio