Andrea de Castro
@andreadcg.bsky.social
PhD student in the Downward lab at the Crick 🐞
Working on KRASi and all Treg things 🧪
Working on KRASi and all Treg things 🧪
Reposted by Andrea de Castro
Oncogenic RAS activity is linked to immune priming and adenosine-driven immune evasion in lung adenocarcinoma https://www.biorxiv.org/content/10.1101/2025.11.25.690426v1
November 26, 2025 at 2:48 PM
Oncogenic RAS activity is linked to immune priming and adenosine-driven immune evasion in lung adenocarcinoma https://www.biorxiv.org/content/10.1101/2025.11.25.690426v1
Reposted by Andrea de Castro
Not turbo cancer but turbo cancer-immunotherapy!
Combining mRNA COVID vaccines with standard-of-care immune therapy overwhelms tumor defenses to improved survival in animal models and large cohorts of people with cancer @nature.com
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Combining mRNA COVID vaccines with standard-of-care immune therapy overwhelms tumor defenses to improved survival in animal models and large cohorts of people with cancer @nature.com
www.nature.com/articles/d41...
www.nature.com/articles/d41...
October 22, 2025 at 6:51 PM
Not turbo cancer but turbo cancer-immunotherapy!
Combining mRNA COVID vaccines with standard-of-care immune therapy overwhelms tumor defenses to improved survival in animal models and large cohorts of people with cancer @nature.com
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Combining mRNA COVID vaccines with standard-of-care immune therapy overwhelms tumor defenses to improved survival in animal models and large cohorts of people with cancer @nature.com
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Andrea de Castro
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
October 6, 2025 at 11:21 AM
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine