To accompany the new ACC/AHA BP guidelines, a practical guide on how to test for Primary Aldosteronism: now recommended for most people with hypertension.

www.jacc.org/doi/10.1016/...

New Primary Aldosteronism Guidelines - simpler, streamlined, and hopefully more pragmatic
academic.oup.com/jcem/advance...

The Impact of Modern Industrialized Dietary Sodium Intake on the Plasma Proteome

academic.oup.com/ajh/advance-...

A pragmatic approach to evaluate for ADRENAL INSUFFICIENCY

Thanks to @irinabancos.bsky.social and Jay Findling for lending their expertise!

yes, same. as seen in this study: www.acpjournals.org/doi/abs/10.7...

Work smarter, not harder!

A low renin with concurrent use of ACEi/ARB is almost certainly some shade of Primary Aldosteronism.

Either way, aldosterone-directed therapy is very likely to provide major clinical benefits

www.ahajournals.org/eprint/TUS6C...

Do patients want to be screened for primary aldosteronism: YES

How much PA can be identified with a direct-to-patient approach: A LOT

Can this approach be implemented nationwide: YES

@JeniferBrown

www.ahajournals.org/doi/10.1161/...

Subclinical primary aldosteronism + Natriuretic peptide deficiency => HYPERTENSION

academic.oup.com/jcem/advance...

Primary Aldosteronism is very common

This interactive case reviews how to recognize it, avoid pitfalls, and effectively help your patients @nejm.org

www.nejm.org/doi/full/10....

(free access with login)

We report detailed human studies to show that a substantial proportion of normotensive people exhibit phenotypic signatures of primary aldosteronism, providing mechanistic implications for the pathogenesis of hypertension and subsequent therapy www.ahajournals.org/doi/10.1161/...