Anaesthesia
@anaesjournal.bsky.social
𝘼𝙣𝙖𝙚𝙨𝙩𝙝𝙚𝙨𝙞𝙖 is the official journal of @assocanaes.bsky.social with comprehensive coverage in peri-operative medicine, critical care and pain.
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#AnSky #MedSky #PainSky #ICUSky #RASky #AirwaySky #PedsAnesSky
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#AnSky #MedSky #PainSky #ICUSky #RASky #AirwaySky #PedsAnesSky
Changes in renal tissue perfusion and oxygenation in response to vasopressor infusion.
In sheep. On cardiopulmonary bypass.
#AnSky #MedSky
doi.org/10.1111/anae...
In sheep. On cardiopulmonary bypass.
#AnSky #MedSky
doi.org/10.1111/anae...
November 24, 2025 at 4:03 PM
Changes in renal tissue perfusion and oxygenation in response to vasopressor infusion.
In sheep. On cardiopulmonary bypass.
#AnSky #MedSky
doi.org/10.1111/anae...
In sheep. On cardiopulmonary bypass.
#AnSky #MedSky
doi.org/10.1111/anae...
Heart-lung bypass lowered kidney blood flow by about half and lowered oxygen levels in the kidney tissue.
The brain's blood flow and oxygen levels were not much changed.
When noradrenaline was used, kidney oxygen levels dropped more than with vasopressin.
#AnSky #MedSky
doi.org/10.1111/anae...
The brain's blood flow and oxygen levels were not much changed.
When noradrenaline was used, kidney oxygen levels dropped more than with vasopressin.
#AnSky #MedSky
doi.org/10.1111/anae...
November 24, 2025 at 1:00 PM
Heart-lung bypass lowered kidney blood flow by about half and lowered oxygen levels in the kidney tissue.
The brain's blood flow and oxygen levels were not much changed.
When noradrenaline was used, kidney oxygen levels dropped more than with vasopressin.
#AnSky #MedSky
doi.org/10.1111/anae...
The brain's blood flow and oxygen levels were not much changed.
When noradrenaline was used, kidney oxygen levels dropped more than with vasopressin.
#AnSky #MedSky
doi.org/10.1111/anae...
Does the choice of vasopressors affect renal oxygenation during cardiopulmonary bypass?
Using an ovine model, researchers found that intra-operative noradrenaline worsens renal medullary tissue oxygenation relative to vasopressin.
#AnSky #MedSky
doi.org/10.1111/anae...
Using an ovine model, researchers found that intra-operative noradrenaline worsens renal medullary tissue oxygenation relative to vasopressin.
#AnSky #MedSky
doi.org/10.1111/anae...
November 24, 2025 at 12:10 PM
Does the choice of vasopressors affect renal oxygenation during cardiopulmonary bypass?
Using an ovine model, researchers found that intra-operative noradrenaline worsens renal medullary tissue oxygenation relative to vasopressin.
#AnSky #MedSky
doi.org/10.1111/anae...
Using an ovine model, researchers found that intra-operative noradrenaline worsens renal medullary tissue oxygenation relative to vasopressin.
#AnSky #MedSky
doi.org/10.1111/anae...
Hypersensitivity reactions to NMDBs in Aotearoa New Zealand
• Suxamethonium accounted for 14% of usage but was responsible for 40% of POHRs
• Rocuronium accounted for 34% of usage and 44% of reactions
• Atracurium accounted for 41% of usage and only 12% of POHRs
#AnSky
doi.org/10.1111/anae...
• Suxamethonium accounted for 14% of usage but was responsible for 40% of POHRs
• Rocuronium accounted for 34% of usage and 44% of reactions
• Atracurium accounted for 41% of usage and only 12% of POHRs
#AnSky
doi.org/10.1111/anae...
November 24, 2025 at 8:47 AM
Hypersensitivity reactions to NMDBs in Aotearoa New Zealand
• Suxamethonium accounted for 14% of usage but was responsible for 40% of POHRs
• Rocuronium accounted for 34% of usage and 44% of reactions
• Atracurium accounted for 41% of usage and only 12% of POHRs
#AnSky
doi.org/10.1111/anae...
• Suxamethonium accounted for 14% of usage but was responsible for 40% of POHRs
• Rocuronium accounted for 34% of usage and 44% of reactions
• Atracurium accounted for 41% of usage and only 12% of POHRs
#AnSky
doi.org/10.1111/anae...
What is "enhanced care"?
Post-anaesthetic care unit (PACU) and overnight intensive recovery units.
What is the impact?
It builds surgical capacity and system resilience.
#AnSky #ICUSky
doi.org/10.1111/anae...
Post-anaesthetic care unit (PACU) and overnight intensive recovery units.
What is the impact?
It builds surgical capacity and system resilience.
#AnSky #ICUSky
doi.org/10.1111/anae...
November 21, 2025 at 7:59 AM
What is "enhanced care"?
Post-anaesthetic care unit (PACU) and overnight intensive recovery units.
What is the impact?
It builds surgical capacity and system resilience.
#AnSky #ICUSky
doi.org/10.1111/anae...
Post-anaesthetic care unit (PACU) and overnight intensive recovery units.
What is the impact?
It builds surgical capacity and system resilience.
#AnSky #ICUSky
doi.org/10.1111/anae...
Target-controlled infusions have been criticised as too slow for RSI, due primarily to the maximum infusion rate of most pumps (~1200 ml/h).
Effect-site concentrations at time-to-peak effect were nearly identical between target-controlled and manual infusions.
#AnSky
doi.org/10.1111/anae...
Effect-site concentrations at time-to-peak effect were nearly identical between target-controlled and manual infusions.
#AnSky
doi.org/10.1111/anae...
November 19, 2025 at 3:00 PM
Target-controlled infusions have been criticised as too slow for RSI, due primarily to the maximum infusion rate of most pumps (~1200 ml/h).
Effect-site concentrations at time-to-peak effect were nearly identical between target-controlled and manual infusions.
#AnSky
doi.org/10.1111/anae...
Effect-site concentrations at time-to-peak effect were nearly identical between target-controlled and manual infusions.
#AnSky
doi.org/10.1111/anae...
One-year follow-up of survival and health-related quality of life in patients with medical conditions admitted acutely to hospital in Malawi and Tanzania
#AnSky #MedSky
doi.org/10.1111/anae...
#AnSky #MedSky
doi.org/10.1111/anae...
November 19, 2025 at 1:32 PM
One-year follow-up of survival and health-related quality of life in patients with medical conditions admitted acutely to hospital in Malawi and Tanzania
#AnSky #MedSky
doi.org/10.1111/anae...
#AnSky #MedSky
doi.org/10.1111/anae...
Rapid sequence induction with target-controlled infusions: a technical simulation study
#AnSky #MedSky
doi.org/10.1111/anae...
#AnSky #MedSky
doi.org/10.1111/anae...
November 19, 2025 at 1:22 PM
Rapid sequence induction with target-controlled infusions: a technical simulation study
#AnSky #MedSky
doi.org/10.1111/anae...
#AnSky #MedSky
doi.org/10.1111/anae...
The following are associated with a reduced incidence of postoperative neurocognitive complications: dexmedetomidine; esketamine; remimazolam; acupuncture; cerebral monitoring; sleep interventions; corticosteroids; antipsychotics; & peripheral nerve blocks.
#AnSky #MedSky
doi.org/10.1111/anae...
#AnSky #MedSky
doi.org/10.1111/anae...
November 18, 2025 at 3:00 PM
The following are associated with a reduced incidence of postoperative neurocognitive complications: dexmedetomidine; esketamine; remimazolam; acupuncture; cerebral monitoring; sleep interventions; corticosteroids; antipsychotics; & peripheral nerve blocks.
#AnSky #MedSky
doi.org/10.1111/anae...
#AnSky #MedSky
doi.org/10.1111/anae...
Reported cases of sugammadex hypersensitivity in the French national pharmacovigilance database
#AnSky #MedSky #sugammadex
doi.org/10.1111/anae...
#AnSky #MedSky #sugammadex
doi.org/10.1111/anae...
November 18, 2025 at 1:00 PM
Reported cases of sugammadex hypersensitivity in the French national pharmacovigilance database
#AnSky #MedSky #sugammadex
doi.org/10.1111/anae...
#AnSky #MedSky #sugammadex
doi.org/10.1111/anae...
Artificial intelligence-assisted tracheal intubation in humans: a prospective observational study of diagnostic accuracy
#AnSky #MedSky #AI
doi.org/10.1111/anae...
#AnSky #MedSky #AI
doi.org/10.1111/anae...
November 18, 2025 at 11:02 AM
Artificial intelligence-assisted tracheal intubation in humans: a prospective observational study of diagnostic accuracy
#AnSky #MedSky #AI
doi.org/10.1111/anae...
#AnSky #MedSky #AI
doi.org/10.1111/anae...
It's happening!!
Artificial intelligence-assisted tracheal intubation in humans: a prospective observational study of diagnostic accuracy
#AnSky #AI #MedSky
doi.org/10.1111/anae...
Artificial intelligence-assisted tracheal intubation in humans: a prospective observational study of diagnostic accuracy
#AnSky #AI #MedSky
doi.org/10.1111/anae...
November 18, 2025 at 9:27 AM
It's happening!!
Artificial intelligence-assisted tracheal intubation in humans: a prospective observational study of diagnostic accuracy
#AnSky #AI #MedSky
doi.org/10.1111/anae...
Artificial intelligence-assisted tracheal intubation in humans: a prospective observational study of diagnostic accuracy
#AnSky #AI #MedSky
doi.org/10.1111/anae...
Among 73,813 patients, 9495 (12.9%) lost the ability to live independently after surgery.
Patients who were classified as underweight or living with obesity class 3 or 4 had an increased likelihood of adverse discharge.
#AnSky #MedSky
doi.org/10.1111/anae...
Patients who were classified as underweight or living with obesity class 3 or 4 had an increased likelihood of adverse discharge.
#AnSky #MedSky
doi.org/10.1111/anae...
November 17, 2025 at 1:01 PM
Among 73,813 patients, 9495 (12.9%) lost the ability to live independently after surgery.
Patients who were classified as underweight or living with obesity class 3 or 4 had an increased likelihood of adverse discharge.
#AnSky #MedSky
doi.org/10.1111/anae...
Patients who were classified as underweight or living with obesity class 3 or 4 had an increased likelihood of adverse discharge.
#AnSky #MedSky
doi.org/10.1111/anae...
Effect of body mass index on postoperative recovery to independent living: a retrospective cohort study
#AnSky #MedSky #BMI
doi.org/10.1111/anae...
#AnSky #MedSky #BMI
doi.org/10.1111/anae...
November 17, 2025 at 12:10 PM
Effect of body mass index on postoperative recovery to independent living: a retrospective cohort study
#AnSky #MedSky #BMI
doi.org/10.1111/anae...
#AnSky #MedSky #BMI
doi.org/10.1111/anae...
There is a U-shaped relationship between BMI and the risk of postoperative loss of independent living.
Patients with mild obesity experienced a lower risk of losing the ability to live independently after surgery.
#AnSky #MedSky
doi.org/10.1111/anae...
Patients with mild obesity experienced a lower risk of losing the ability to live independently after surgery.
#AnSky #MedSky
doi.org/10.1111/anae...
November 17, 2025 at 11:02 AM
There is a U-shaped relationship between BMI and the risk of postoperative loss of independent living.
Patients with mild obesity experienced a lower risk of losing the ability to live independently after surgery.
#AnSky #MedSky
doi.org/10.1111/anae...
Patients with mild obesity experienced a lower risk of losing the ability to live independently after surgery.
#AnSky #MedSky
doi.org/10.1111/anae...
Here is the first consensus-based core outcome set for airway management research, with agreed definitions and measurement instruments.
This will harmonise evidence synthesis and improve the translatability of findings to improve clinical care.
#AnSky #AirwaySky
doi.org/10.1111/anae...
This will harmonise evidence synthesis and improve the translatability of findings to improve clinical care.
#AnSky #AirwaySky
doi.org/10.1111/anae...
November 14, 2025 at 7:03 AM
Here is the first consensus-based core outcome set for airway management research, with agreed definitions and measurement instruments.
This will harmonise evidence synthesis and improve the translatability of findings to improve clinical care.
#AnSky #AirwaySky
doi.org/10.1111/anae...
This will harmonise evidence synthesis and improve the translatability of findings to improve clinical care.
#AnSky #AirwaySky
doi.org/10.1111/anae...
Cross sensitivity between neuromuscular blocking agents
If a patient has had a POHR to:
• rocuronium, suxamethonium or vecuronium, then atracurium is the lowest risk alternative
• atracurium, then rocuronium and suxamethonium are low risk alternatives
#AnSky
doi.org/10.1111/anae...
If a patient has had a POHR to:
• rocuronium, suxamethonium or vecuronium, then atracurium is the lowest risk alternative
• atracurium, then rocuronium and suxamethonium are low risk alternatives
#AnSky
doi.org/10.1111/anae...
November 13, 2025 at 7:49 PM
Cross sensitivity between neuromuscular blocking agents
If a patient has had a POHR to:
• rocuronium, suxamethonium or vecuronium, then atracurium is the lowest risk alternative
• atracurium, then rocuronium and suxamethonium are low risk alternatives
#AnSky
doi.org/10.1111/anae...
If a patient has had a POHR to:
• rocuronium, suxamethonium or vecuronium, then atracurium is the lowest risk alternative
• atracurium, then rocuronium and suxamethonium are low risk alternatives
#AnSky
doi.org/10.1111/anae...
The chance of having an allergic reaction to a neuromuscular blocking drug is:
• suxamethonium: ~1 in 1500 people
• rocuronium: ~1 in 3300 people
• atracurium: ~1 in 15,000 people
Women were up to eight times more likely to have a reaction than men.
#AnSky #MedSky
doi.org/10.1111/anae...
• suxamethonium: ~1 in 1500 people
• rocuronium: ~1 in 3300 people
• atracurium: ~1 in 15,000 people
Women were up to eight times more likely to have a reaction than men.
#AnSky #MedSky
doi.org/10.1111/anae...
November 12, 2025 at 9:06 AM
The chance of having an allergic reaction to a neuromuscular blocking drug is:
• suxamethonium: ~1 in 1500 people
• rocuronium: ~1 in 3300 people
• atracurium: ~1 in 15,000 people
Women were up to eight times more likely to have a reaction than men.
#AnSky #MedSky
doi.org/10.1111/anae...
• suxamethonium: ~1 in 1500 people
• rocuronium: ~1 in 3300 people
• atracurium: ~1 in 15,000 people
Women were up to eight times more likely to have a reaction than men.
#AnSky #MedSky
doi.org/10.1111/anae...
• There is a significant difference between the rates of peri-operative hypersensitivity reactions with rocuronium and suxamethonium vs. atracurium.
• Females may be higher risk than males of reacting to neuromuscular blocking drugs.
#AnSky
doi.org/10.1111/anae...
• Females may be higher risk than males of reacting to neuromuscular blocking drugs.
#AnSky
doi.org/10.1111/anae...
November 12, 2025 at 7:03 AM
• There is a significant difference between the rates of peri-operative hypersensitivity reactions with rocuronium and suxamethonium vs. atracurium.
• Females may be higher risk than males of reacting to neuromuscular blocking drugs.
#AnSky
doi.org/10.1111/anae...
• Females may be higher risk than males of reacting to neuromuscular blocking drugs.
#AnSky
doi.org/10.1111/anae...
Hyperangulated videolaryngoscopy: stylet first until benefit of bougie is shown
"...the current challenge for the wider community of anaesthetists ... is not mastery of HAVL but access to devices, routine use, gaining familiarly and developing competence."
#AnSky
ttps://doi.org/10.1111/anae.70062
"...the current challenge for the wider community of anaesthetists ... is not mastery of HAVL but access to devices, routine use, gaining familiarly and developing competence."
#AnSky
ttps://doi.org/10.1111/anae.70062
November 10, 2025 at 12:16 PM
Hyperangulated videolaryngoscopy: stylet first until benefit of bougie is shown
"...the current challenge for the wider community of anaesthetists ... is not mastery of HAVL but access to devices, routine use, gaining familiarly and developing competence."
#AnSky
ttps://doi.org/10.1111/anae.70062
"...the current challenge for the wider community of anaesthetists ... is not mastery of HAVL but access to devices, routine use, gaining familiarly and developing competence."
#AnSky
ttps://doi.org/10.1111/anae.70062
Arterial catheter infection rates remain notably higher than those of peripheral intravenous catheters, which have an incidence of approximately 0.03%.
Why is a higher infection risk in arterial catheters tolerated?
#AnSky #ICUSky
doi.org/10.1111/anae...
Why is a higher infection risk in arterial catheters tolerated?
#AnSky #ICUSky
doi.org/10.1111/anae...
November 7, 2025 at 9:06 AM
Arterial catheter infection rates remain notably higher than those of peripheral intravenous catheters, which have an incidence of approximately 0.03%.
Why is a higher infection risk in arterial catheters tolerated?
#AnSky #ICUSky
doi.org/10.1111/anae...
Why is a higher infection risk in arterial catheters tolerated?
#AnSky #ICUSky
doi.org/10.1111/anae...
Arterial catheter complications:
• 13/100 catheters failed for any reason
• 20/100 catheters failed for reasons not caused by infection
• bloodstream infections - 1/100 catheters
• local infections (around the area where the catheter goes in) - 1/100 cases
#ICUSky #AnSky
doi.org/10.1111/anae...
• 13/100 catheters failed for any reason
• 20/100 catheters failed for reasons not caused by infection
• bloodstream infections - 1/100 catheters
• local infections (around the area where the catheter goes in) - 1/100 cases
#ICUSky #AnSky
doi.org/10.1111/anae...
November 6, 2025 at 9:06 AM
Arterial catheter complications:
• 13/100 catheters failed for any reason
• 20/100 catheters failed for reasons not caused by infection
• bloodstream infections - 1/100 catheters
• local infections (around the area where the catheter goes in) - 1/100 cases
#ICUSky #AnSky
doi.org/10.1111/anae...
• 13/100 catheters failed for any reason
• 20/100 catheters failed for reasons not caused by infection
• bloodstream infections - 1/100 catheters
• local infections (around the area where the catheter goes in) - 1/100 cases
#ICUSky #AnSky
doi.org/10.1111/anae...
On MRI scans, people with chronic pain often had patterns that were like the patterns seen in people with Alzheimer's disease: less grey brain tissue, weaker white brain tissue, and signs of older brain age in places such as the hippocampus.
#AnSky
doi.org/10.1111/anae...
#AnSky
doi.org/10.1111/anae...
October 31, 2025 at 4:02 PM
On MRI scans, people with chronic pain often had patterns that were like the patterns seen in people with Alzheimer's disease: less grey brain tissue, weaker white brain tissue, and signs of older brain age in places such as the hippocampus.
#AnSky
doi.org/10.1111/anae...
#AnSky
doi.org/10.1111/anae...
Brain health in adults with chronic pain
For structural MRI studies, smaller grey matter volumes were found in the chronic pain group compared with healthy controls in most studies.
#AnSky
doi.org/10.1111/anae...
For structural MRI studies, smaller grey matter volumes were found in the chronic pain group compared with healthy controls in most studies.
#AnSky
doi.org/10.1111/anae...
October 31, 2025 at 3:03 PM
Brain health in adults with chronic pain
For structural MRI studies, smaller grey matter volumes were found in the chronic pain group compared with healthy controls in most studies.
#AnSky
doi.org/10.1111/anae...
For structural MRI studies, smaller grey matter volumes were found in the chronic pain group compared with healthy controls in most studies.
#AnSky
doi.org/10.1111/anae...
Machine learning and the NHS pre-operative assessment
"Presenting subgroup-stratified performance and quantifying the warning flag system would enhance transparency, support safe adoption and broaden the impact on peri-operative services and health system planning."
#AnSky
doi.org/10.1111/anae...
"Presenting subgroup-stratified performance and quantifying the warning flag system would enhance transparency, support safe adoption and broaden the impact on peri-operative services and health system planning."
#AnSky
doi.org/10.1111/anae...
October 31, 2025 at 12:10 PM
Machine learning and the NHS pre-operative assessment
"Presenting subgroup-stratified performance and quantifying the warning flag system would enhance transparency, support safe adoption and broaden the impact on peri-operative services and health system planning."
#AnSky
doi.org/10.1111/anae...
"Presenting subgroup-stratified performance and quantifying the warning flag system would enhance transparency, support safe adoption and broaden the impact on peri-operative services and health system planning."
#AnSky
doi.org/10.1111/anae...