Many molecular reactions in cells are tethered, often by #IDR. If 2 tethers are tied together (imagine handcuffed arms ⛓️💥), does this enhance or suppress their reactions? Formin, one of the major families of #cytoskeleton builders in eukaryotes, does exactly this.
December 3, 2025 at 7:00 PM
Many molecular reactions in cells are tethered, often by #IDR. If 2 tethers are tied together (imagine handcuffed arms ⛓️💥), does this enhance or suppress their reactions? Formin, one of the major families of #cytoskeleton builders in eukaryotes, does exactly this.
A remarkably simple question, "What is the likelihood landscape for the basic bursting transcription model?", reveals surprisingly complex underlying structure, with implications for the limits of what single-cell data can tell you.
December 2, 2025 at 3:58 AM
A remarkably simple question, "What is the likelihood landscape for the basic bursting transcription model?", reveals surprisingly complex underlying structure, with implications for the limits of what single-cell data can tell you.
An idea is gaining ground that nucleosomes control the genome, via not just local access, but long-range conformation, and not just their density but their specific placement too. Read more!
September 8, 2025 at 6:03 PM
An idea is gaining ground that nucleosomes control the genome, via not just local access, but long-range conformation, and not just their density but their specific placement too. Read more!