Katie Bogue's new preprint with Margot Quinlan and Bryan Christian, out now!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Impact of N-terminal dimerization on formin homology 1 domain polymer dynamics and actin assembly
Many proteins contain intrinsically disordered regions (IDRs) that lack stable 3-dimensional structure. IDR behavior is poorly understood, leading to challenges for biochemical and computational analy...
www.biorxiv.org
December 3, 2025 at 7:00 PM
Katie Bogue's new preprint with Margot Quinlan and Bryan Christian, out now!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Very excited to be involved in this new work led by Junhao Gu and Elizabeth Read, out this week in Bioinformatics. Collaboration with Timothy Downing, Chris Miles and others!
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
Scalable inference and identifiability of kinetic parameters for transcriptional bursting from single cell data
AbstractMotivation. Stochastic gene expression and cell-to-cell heterogeneity have attracted increased interest in recent years, enabled by advances in sin
academic.oup.com
December 2, 2025 at 3:58 AM
Very excited to be involved in this new work led by Junhao Gu and Elizabeth Read, out this week in Bioinformatics. Collaboration with Timothy Downing, Chris Miles and others!
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
We can make the flexibility of a model match the hypothesis being tested -- more flexibility is not always better, if it prohibits rejection of the hypothesis. Here is one simple case involving T cells where it made a difference!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 8, 2025 at 6:07 PM
We can make the flexibility of a model match the hypothesis being tested -- more flexibility is not always better, if it prohibits rejection of the hypothesis. Here is one simple case involving T cells where it made a difference!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Brady Berg's new work is out on biorxiv! Shows a surprising connection between astral architecture and percolation in the cytoskeleton.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 8, 2025 at 6:06 PM
Brady Berg's new work is out on biorxiv! Shows a surprising connection between astral architecture and percolation in the cytoskeleton.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Our paper, lead by Jack Corrette, with Timothy Downing and Andrew Spakowitz is out in Nucleic Acids Research!
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Nucleosome placement and polymer mechanics explain genomic contacts on 100 kb scales
Abstract. The 3D organization of the genome—in particular, which two regions of DNA are in contact with each other—plays a role in regulating gene expressi
academic.oup.com
September 8, 2025 at 6:03 PM
Our paper, lead by Jack Corrette, with Timothy Downing and Andrew Spakowitz is out in Nucleic Acids Research!
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...