Abdalla Alkhawaja
@alkhawaja.bsky.social
Bioinformatics and Computational Biology PhD candidate at UNC-CH
Reposted by Abdalla Alkhawaja
I'm become quite partial to cell-type-biased (population-biased) terminology rather than cell-type-specific (population-specific) when it comes to QTLs, because it reflects better that these are a result of power, rather than biological differences.
July 8, 2025 at 4:59 PM
I'm become quite partial to cell-type-biased (population-biased) terminology rather than cell-type-specific (population-specific) when it comes to QTLs, because it reflects better that these are a result of power, rather than biological differences.
Reposted by Abdalla Alkhawaja
It was used to indicate different effect sizes (not statistical 'bias'). So population-biased eQTLs, sex-biased eQTLs = inclusive of poss 'pop-/sex-'specific. There was lots of discussion about how to refer to these. 'specific' was a hard "no" for many of the reasons mentioned above in this thread.
July 8, 2025 at 8:28 PM
It was used to indicate different effect sizes (not statistical 'bias'). So population-biased eQTLs, sex-biased eQTLs = inclusive of poss 'pop-/sex-'specific. There was lots of discussion about how to refer to these. 'specific' was a hard "no" for many of the reasons mentioned above in this thread.
Stop by PB1200 if you are interested about the genetic regulation of chromatin accessibility and gene expression using single nucleus multiome sequencing in the liver!
Looking forward to meeting you
#ASHG2023
Looking forward to meeting you
#ASHG2023
November 4, 2023 at 1:27 PM
Stop by PB1200 if you are interested about the genetic regulation of chromatin accessibility and gene expression using single nucleus multiome sequencing in the liver!
Looking forward to meeting you
#ASHG2023
Looking forward to meeting you
#ASHG2023