Alice Perucca
aliperri.bsky.social
Alice Perucca
@aliperri.bsky.social
Biologist working in (cancer) mechanobiology - PhD student @ibecbarcelona.eu in Integrative Cell and Tissue Dynamics group

Alumni @utrechtuniversity.bsky.social
7/7 Friends 🎈 I am incredibly grateful to have worked alongside my wonderful co-first author, @oriolmb.bsky.social. This project has been a surprising journey, filled with challenges, triumphs, and lots of laughs. Cheers to the friendships made through science!
February 10, 2025 at 4:42 PM
4/7: MIRO enables high throughput testing of #immunotherapies, opening new possibilities for personalized cancer treatments.
As a proof of concept, we restored anti-cancer immunity in resistant/immune-excluded HER2+ breast cancer with IL2 treatment. 💪
🎥 Immune cell migration upon treatment
February 10, 2025 at 4:42 PM
3/7: Why MIRO is unique?
✅ Immunocompetent: tracks #ImmuneCells movement & interactions
✅ Cells self-organize & build their own extra-cellular matrix
✅ Cost-effective, reproducible & user-friendly
🎥 cellular organization in MIRO
#ECM #TumorEcosystem
February 10, 2025 at 4:42 PM
2/7: MIRO is an open fluidic device that models the tumour-stroma interface using patient-derived cells. This allows us to recreate aspects of the #TumorMicroenvironment and study immune cell interactions in the lab. 🔎🧫 #Microfluidics #OnChip
February 10, 2025 at 4:42 PM