Alex Y. Kreins
@alexyema.bsky.social
Wellcome Trust career development fellow treating #IEI patients (athymia/SCID) @GreatOrmondSt & translational research @uclchildhealth to improve their outcomes!
https://profiles.ucl.ac.uk/70769-alexandra-kreins
https://profiles.ucl.ac.uk/70769-alexandra-kreins
For the full story 👉 doi.org/10.1084/jem....
Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency | Journal of Experimental Medicine | Rockefeller University Press
Dominant negative variants in ITPR3, encoding a subunit of the IP3 receptor, cause Ca2+ channel leakiness resulting in ER store depletion and impaired T ce
doi.org
February 13, 2025 at 9:26 PM
For the full story 👉 doi.org/10.1084/jem....