Alexis Rohou
@alexisrohou.bsky.social
CryoEM and structural biology methods, drug discovery. Also: Celtics, Camus, rocksteady, drum and bass. He, him, his.
My celebrity birthday twin
January 13, 2025 at 4:30 AM
My celebrity birthday twin
Oh my. This is just gorgeous from Misha Kudryashev's lab (I don't think he's here yet?). Love to see it. V ATPase resolved directly in synaptic vesicles 🤤 Lots of other neat observations in there also. Congrats to all involved! www.pnas.org/doi/10.1073/...
December 2, 2024 at 4:30 AM
Oh my. This is just gorgeous from Misha Kudryashev's lab (I don't think he's here yet?). Love to see it. V ATPase resolved directly in synaptic vesicles 🤤 Lots of other neat observations in there also. Congrats to all involved! www.pnas.org/doi/10.1073/...
This looks great! Thanks for choosing a permissive license and also cannot wait for this:
March 20, 2024 at 2:32 PM
This looks great! Thanks for choosing a permissive license and also cannot wait for this:
My brain has too many tabs open, 4 of them are frozen & I have no idea where the music is coming from
December 31, 2023 at 12:52 AM
My brain has too many tabs open, 4 of them are frozen & I have no idea where the music is coming from
Let the dry brining beginning!
November 21, 2023 at 3:53 AM
Let the dry brining beginning!
Look what arrived today @cjrlab.bsky.social !
November 18, 2023 at 4:27 AM
Look what arrived today @cjrlab.bsky.social !
Hey @united - your United Cares website appears broken on Chrome (incl incognito mode) - I have been getting this error every time before I can even complete the form... help?
November 12, 2024 at 1:53 PM
Hey @united - your United Cares website appears broken on Chrome (incl incognito mode) - I have been getting this error every time before I can even complete the form... help?
Is the @EMDB_EMPIAR 3D-view component in the web frontend open source? Or based on an open-source project?
November 12, 2024 at 1:53 PM
Is the @EMDB_EMPIAR 3D-view component in the web frontend open source? Or based on an open-source project?
House hunting in California makes it clear how explicitly racist this land was. Below the key clause of a 1924 covenant I just came across. "The above described property shall not be transferred to a person or persons not of the Caucasian race".
November 12, 2024 at 1:53 PM
House hunting in California makes it clear how explicitly racist this land was. Below the key clause of a 1924 covenant I just came across. "The above described property shall not be transferred to a person or persons not of the Caucasian race".
Just finished one that I think took me ~6 hours, over 3 days. Unfortunately the authors didn't submit to @biorxivpreprint. Grrr. On the plus side, I saw this on the publisher's reviewer portal for the first time, which I thought was great! I continue to sign all my reviews...
November 12, 2024 at 4:09 PM
Just finished one that I think took me ~6 hours, over 3 days. Unfortunately the authors didn't submit to @biorxivpreprint. Grrr. On the plus side, I saw this on the publisher's reviewer portal for the first time, which I thought was great! I continue to sign all my reviews...
Hey @gmail, it's "these data", not "this data"
November 12, 2024 at 2:05 PM
Hey @gmail, it's "these data", not "this data"
Some crazy auto-complete action in Google when typing "bioRxiv" into the search box. I can't believe this is the most common thing folks are asking about @biorxivpreprint. How sad.
November 12, 2024 at 2:05 PM
Some crazy auto-complete action in Google when typing "bioRxiv" into the search box. I can't believe this is the most common thing folks are asking about @biorxivpreprint. How sad.
Here's another TRPA1 story from our drug discovery pipeline that includes a #cryoEM structure, which illuminates the MOA of the small molecule ligand. This is the 3rd distinct TRPA1 binding pocket we have described in recent publications!...
November 12, 2024 at 2:16 PM
Here's another TRPA1 story from our drug discovery pipeline that includes a #cryoEM structure, which illuminates the MOA of the small molecule ligand. This is the 3rd distinct TRPA1 binding pocket we have described in recent publications!...
Yikes. This paper was submitted several months (June) after I am certain beyond doubt the author was aware of the FSC-FDR manuscript (bioRxiv and JSB submt in March, accepted July) https://www.biorxiv.org/content/10.1101/2020.03.13.990705v1 which seems highly relevant to another...
November 12, 2024 at 2:54 PM
Yikes. This paper was submitted several months (June) after I am certain beyond doubt the author was aware of the FSC-FDR manuscript (bioRxiv and JSB submt in March, accepted July) https://www.biorxiv.org/content/10.1101/2020.03.13.990705v1 which seems highly relevant to another...
@MendeleySupport what's with DOI "Lookup failed" with valid DOIs? E.g. 10.1101/2020.05.21.106740 is valid, resolved by <a href="http://doi.org," class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://doi.org, but Mendeley (1.19.4) gives "Lookup Failed"
November 12, 2024 at 2:27 PM
@MendeleySupport what's with DOI "Lookup failed" with valid DOIs? E.g. 10.1101/2020.05.21.106740 is valid, resolved by <a href="http://doi.org," class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://doi.org, but Mendeley (1.19.4) gives "Lookup Failed"
Welp - I've found a limit in Jira... what do you mean my story can't be longer than 32,767 characters?!?
November 12, 2024 at 2:27 PM
Welp - I've found a limit in Jira... what do you mean my story can't be longer than 32,767 characters?!?
I've only just begun parsing this manuscript. I'm obviously very interested in understanding the impact of the monochromator and aberration corrector. This figure seems key, but I am not sure it's a fair comparison....
https://www.biorxiv.org/content/10.1101/2020.05.21.106740v1
https://www.biorxiv.org/content/10.1101/2020.05.21.106740v1
November 12, 2024 at 2:27 PM
I've only just begun parsing this manuscript. I'm obviously very interested in understanding the impact of the monochromator and aberration corrector. This figure seems key, but I am not sure it's a fair comparison....
https://www.biorxiv.org/content/10.1101/2020.05.21.106740v1
https://www.biorxiv.org/content/10.1101/2020.05.21.106740v1
What's the point of this atom inclusion score anyway? Can we just get rid of it? With my favored threshold (for visualization), I get ~50% red bars in PDB validation report. Grrrrr.
November 12, 2024 at 3:13 PM
What's the point of this atom inclusion score anyway? Can we just get rid of it? With my favored threshold (for visualization), I get ~50% red bars in PDB validation report. Grrrrr.
It's happening, we're surging just at the right moment!
November 12, 2024 at 2:39 PM
It's happening, we're surging just at the right moment!
First bee of the season on my lavender. May not have the Nobel pedigree of LMBees, but I still love my local bees!
November 12, 2024 at 2:39 PM
First bee of the season on my lavender. May not have the Nobel pedigree of LMBees, but I still love my local bees!