StructGuy: Data leakage free prediction of functional effects of genetic variants. https://www.biorxiv.org/content/10.64898/2025.12.01.691563v1

We are excited that our paper "Cleanifier: Contamination removal from microbial sequences using spaced seeds of a human pangenome index" is now published at Bioinformatics (doi.org/10.1093/bioi...).

You can find it at gitlab (gitlab.com/rahmannlab/c...) or install it via PyPI or Bioconda.

Detection of alternative splicing: deep sequencing or deep learning? https://www.biorxiv.org/content/10.1101/2025.08.23.671909v1

SingleRust: A High-Performance Toolkit for Single-Cell Data Analysis at Scale https://www.biorxiv.org/content/10.1101/2025.08.04.668429v1

Our preprint is finally out for SingleRust:
doi.org/10.1101/2025...

Stay tuned: @singlerust.bsky.social, @ianfd.bsky.social
github.com/SingleRust

What an exciting week it's been at the #ISMBECCB2025 conference! The Drug Bioinformatics group had a fantastic presence, with six members presenting their latest work across various COSIs.

www.linkedin.com/feed/update/...

This week I presented DataSAIL at the #ISMBECCB2025 conference in #Liverpool
It has been an amazing chance and experience to meet many people working on information leakage. And getting great ideas to extend it

Nicely supervised by & colaborated with @dbblumenthal.bsky.social @ok55991.bsky.social

I am very excited to share the publication of our tool StructMAn 2.0 in the NAR webserver issue (10.1093/nar/gkaf381). If you want to annotate protein structures to protein sequences or if you are looking for structural evidence for PPIs, consider using: tools.helmholtz-hips.de/structman/

DataSAIL is out in @naturecomms.bsky.social
Since the preprint, we have improved the work a lot, thanks to countless reviewers and feedback.

You can find it here: nature.com/articles/s41...

Thanks, @dbblumenthal.bsky.social and @ok55991.bsky.social, for helping and supervising me on this journey.