Thank you, Judith!

Link to publication and short graphical abstract below!
www.cell.com/immunity/ful...

Hello there.

This is fantastic, could you please add me alercher@bsky.social - thx!

...aaaand, we even made the cover at Immunity!
Big thanks to all the funding agencies, collaborators, mentors and friends who made this paper possible!

These findings shed light on how respiratory viral infections cross-influence their disease pathology via innate immune memory with implications for pandemic preparedness.
Press release: www.rockefeller.edu/news/36603-c...

This allowed recovered mice to be better at combatting secondary influenza A virus infection - an effect that seemed to be solely mediated by recovered alveolar macrophages, independent of SARS2-memory T cells!

We found that alveolar macrophages retain epigenetic remodeling post COVID-19 that allows them to hyper-induce antiviral genes after encountering a secondary viral pathogen

This allowed recovered mice to be better at combatting secondary influenza A virus infection - an effect that seemed to be solely mediated by recovered alveolar macrophages, independent of SARS2-memory T cells!

We found that alveolar macrophages retain epigenetic remodeling post COVID-19 that allows them to hyper-induce antiviral genes after encountering a secondary viral pathogen

Thanks for sharing and appreciating our study!

These findings highlight long-lasting consequences of past #SARSCoV2 infection and have implications for seasonality of respiratory infections.

This study was a strong team effort by the #RiceLab, #JosefowiczLab and #RosenbergLab