The American Journal of Pathology
@ajpathology.bsky.social
The official journal of the American Society for Investigative Pathology, publishing mechanistic discoveries in basic and translational pathobiology.
Read the latest #PressRelease from @ajpathology.bsky.social and @elsevierconnect.bsky.social: New Study Elucidates Obesity’s Role in Fueling Breast Cancer Progression.
Full release: https://shorturl.at/dkGNS
Full release: https://shorturl.at/dkGNS
November 10, 2025 at 5:55 PM
Read the latest #PressRelease from @ajpathology.bsky.social and @elsevierconnect.bsky.social: New Study Elucidates Obesity’s Role in Fueling Breast Cancer Progression.
Full release: https://shorturl.at/dkGNS
Full release: https://shorturl.at/dkGNS
#Neurodegenerative Theme Review: Brain Connectivity, Neural Networks, and Resilience in Aging and Neurodegeneration. From @asipath.bsky.social member Dr. Christi Kolarcik.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00027-6/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00027-6/fulltext
November 10, 2025 at 2:47 PM
#Neurodegenerative Theme Review: Brain Connectivity, Neural Networks, and Resilience in Aging and Neurodegeneration. From @asipath.bsky.social member Dr. Christi Kolarcik.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00027-6/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00027-6/fulltext
Deadline extended!
The Spatial Pathobiology #callforpapers is still open. Submit your work by November 30th for inclusion in this upcoming theme issue.
https://www.editorialmanager.com/ajpa/default2.aspx
The Spatial Pathobiology #callforpapers is still open. Submit your work by November 30th for inclusion in this upcoming theme issue.
https://www.editorialmanager.com/ajpa/default2.aspx
November 7, 2025 at 2:33 PM
Deadline extended!
The Spatial Pathobiology #callforpapers is still open. Submit your work by November 30th for inclusion in this upcoming theme issue.
https://www.editorialmanager.com/ajpa/default2.aspx
The Spatial Pathobiology #callforpapers is still open. Submit your work by November 30th for inclusion in this upcoming theme issue.
https://www.editorialmanager.com/ajpa/default2.aspx
#LegacyContent: Glucocorticoid Receptor Signaling Is Critical for Mouse Corneal Development, Inhibition of Inflammatory Response, and Neovascularization of the Cornea.
Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00236-0/fulltext
Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00236-0/fulltext
October 31, 2025 at 7:22 PM
#LegacyContent: Glucocorticoid Receptor Signaling Is Critical for Mouse Corneal Development, Inhibition of Inflammatory Response, and Neovascularization of the Cornea.
Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00236-0/fulltext
Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00236-0/fulltext
DEADLINE EXTENDED!
Spatial Pathobiology #Callforpapers new deadline: November 30, 2025.
Submit your work today: https://www.editorialmanager.com/ajpa/default2.aspx
Spatial Pathobiology #Callforpapers new deadline: November 30, 2025.
Submit your work today: https://www.editorialmanager.com/ajpa/default2.aspx
October 31, 2025 at 4:06 PM
DEADLINE EXTENDED!
Spatial Pathobiology #Callforpapers new deadline: November 30, 2025.
Submit your work today: https://www.editorialmanager.com/ajpa/default2.aspx
Spatial Pathobiology #Callforpapers new deadline: November 30, 2025.
Submit your work today: https://www.editorialmanager.com/ajpa/default2.aspx
The November issue of AJP is now live! This is a special issue focused on neuropathology.
Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7
On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid
Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7
On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid
October 30, 2025 at 7:28 PM
The November issue of AJP is now live! This is a special issue focused on neuropathology.
Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7
On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid
Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7
On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid
Read the latest #PressRelease from @ajpathology.bsky.social and @elsevierconnect.bsky.social: Researchers Identify Perineural Pathway That Fuels HIV Persistence Despite Treatment.
Full release: https://shorturl.at/x1kYh
Full release: https://shorturl.at/x1kYh
October 29, 2025 at 8:34 PM
Read the latest #PressRelease from @ajpathology.bsky.social and @elsevierconnect.bsky.social: Researchers Identify Perineural Pathway That Fuels HIV Persistence Despite Treatment.
Full release: https://shorturl.at/x1kYh
Full release: https://shorturl.at/x1kYh
#ArticleinPress: Intra-host genomic variation of Haemophilus influenzae isolates from asymptomatic nasopharyngeal carriers involves genes encoding proteins with diverse inferred functions.
#OpenAccess text: https://loom.ly/1s7mAIM
#OpenAccess text: https://loom.ly/1s7mAIM
October 28, 2025 at 1:24 PM
#ArticleinPress: Intra-host genomic variation of Haemophilus influenzae isolates from asymptomatic nasopharyngeal carriers involves genes encoding proteins with diverse inferred functions.
#OpenAccess text: https://loom.ly/1s7mAIM
#OpenAccess text: https://loom.ly/1s7mAIM
#LegacyContent: Sequential Patching Lattice for Image Classification and Enquiry: Streamlining Digital Pathology Image Processing. Authors from @mayoclinic.org.
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00238-4/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00238-4/fulltext
October 27, 2025 at 6:58 PM
#LegacyContent: Sequential Patching Lattice for Image Classification and Enquiry: Streamlining Digital Pathology Image Processing. Authors from @mayoclinic.org.
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00238-4/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00238-4/fulltext
#LegacyContent: The Role of Twist1 in Chronic Pancreatitis–Associated Pancreatic Stellate Cells. Authors from @cedarssinaicancer.bsky.social.
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00234-7/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00234-7/fulltext
October 26, 2025 at 5:02 PM
#LegacyContent: The Role of Twist1 in Chronic Pancreatitis–Associated Pancreatic Stellate Cells. Authors from @cedarssinaicancer.bsky.social.
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00234-7/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00234-7/fulltext
#LegacyContent: Lactate Contributes to RIPC–Mediated Protection Against Myocardial Ischemia Reperfusion Injury by Facilitating Autophagy via the AMP-Activated Protein Kinase–Mammalian Target of Rapamycin–Transcription Factor EB–Connexin 43 Axis.
https://loom.ly/4ofKbWc
https://loom.ly/4ofKbWc
October 25, 2025 at 4:45 PM
#LegacyContent: Lactate Contributes to RIPC–Mediated Protection Against Myocardial Ischemia Reperfusion Injury by Facilitating Autophagy via the AMP-Activated Protein Kinase–Mammalian Target of Rapamycin–Transcription Factor EB–Connexin 43 Axis.
https://loom.ly/4ofKbWc
https://loom.ly/4ofKbWc
#ArticleinPress: Hepatocyte-Specific MET Deletion Exacerbates Acetaminophen-Induced Hepatotoxicity in Mice.
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00367-0/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00367-0/fulltext
October 24, 2025 at 7:31 PM
#ArticleinPress: Hepatocyte-Specific MET Deletion Exacerbates Acetaminophen-Induced Hepatotoxicity in Mice.
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00367-0/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00367-0/fulltext
#LegacyContent: Single-Nucleus RNA Sequencing Reveals Loss of Distal Convoluted Tubule 1 Renal Tubules in HIV Viral Protein R Transgenic Mice.
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00237-2/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00237-2/fulltext
October 24, 2025 at 1:34 PM
#LegacyContent: Single-Nucleus RNA Sequencing Reveals Loss of Distal Convoluted Tubule 1 Renal Tubules in HIV Viral Protein R Transgenic Mice.
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00237-2/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00237-2/fulltext
#ArticleinPress: Targeting RORγ to Boost Regulatory T cells and Ameliorate Diabetic Retinopathy in Mice. Authors from @unimelb.bsky.social.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00363-3/abstract
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00363-3/abstract
October 23, 2025 at 7:31 PM
#ArticleinPress: Targeting RORγ to Boost Regulatory T cells and Ameliorate Diabetic Retinopathy in Mice. Authors from @unimelb.bsky.social.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00363-3/abstract
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00363-3/abstract
#LegacyContent: Cardiac Atrophy, Dysfunction, and Metabolic Impairments: A Cancer-Induced Cardiomyopathy Phenotype. @dalhousie.bsky.social
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00241-4/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00241-4/fulltext
October 23, 2025 at 5:55 PM
#LegacyContent: Cardiac Atrophy, Dysfunction, and Metabolic Impairments: A Cancer-Induced Cardiomyopathy Phenotype. @dalhousie.bsky.social
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00241-4/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00241-4/fulltext
#CallforPapers #SpatialPathobiology
Send in your original research related to spatial pathobiology in mechanisms of disease for an upcoming theme issue.
https://www.editorialmanager.com/ajpa/default2.aspx
Send in your original research related to spatial pathobiology in mechanisms of disease for an upcoming theme issue.
https://www.editorialmanager.com/ajpa/default2.aspx
October 17, 2025 at 4:49 PM
#CallforPapers #SpatialPathobiology
Send in your original research related to spatial pathobiology in mechanisms of disease for an upcoming theme issue.
https://www.editorialmanager.com/ajpa/default2.aspx
Send in your original research related to spatial pathobiology in mechanisms of disease for an upcoming theme issue.
https://www.editorialmanager.com/ajpa/default2.aspx
The substructure of the endothelial glycocalyx in rat aorta and its interaction with the low-density lipoproteins (LDL).
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00237-8/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00237-8/fulltext
October 8, 2025 at 7:10 PM
The substructure of the endothelial glycocalyx in rat aorta and its interaction with the low-density lipoproteins (LDL).
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00237-8/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00237-8/fulltext
#ArticleinPress: Periostin deletion reduces corneal opacity and the infiltration of immune cells.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00364-5/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00364-5/fulltext
October 8, 2025 at 1:09 PM
#ArticleinPress: Periostin deletion reduces corneal opacity and the infiltration of immune cells.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00364-5/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00364-5/fulltext
#ArticleinPress: Decreased Glycolysis due to LDHA m6A methylation in Endometrium of endometriosis impairs its decidualization and contributes to related infertility
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00359-1/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00359-1/fulltext
October 7, 2025 at 7:24 PM
#ArticleinPress: Decreased Glycolysis due to LDHA m6A methylation in Endometrium of endometriosis impairs its decidualization and contributes to related infertility
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00359-1/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00359-1/fulltext
The image on the October cover is from "Hyperactivation of Transforming Growth Factor-β–Activated Kinase 1 Causes Skeletal Muscle Pathology Reminiscent of Inflammatory Myopathies"
Read the #openaccess text here: ajp.amjpathol.org/article/S000...
Read the #openaccess text here: ajp.amjpathol.org/article/S000...
October 7, 2025 at 5:06 PM
The image on the October cover is from "Hyperactivation of Transforming Growth Factor-β–Activated Kinase 1 Causes Skeletal Muscle Pathology Reminiscent of Inflammatory Myopathies"
Read the #openaccess text here: ajp.amjpathol.org/article/S000...
Read the #openaccess text here: ajp.amjpathol.org/article/S000...
Endothelial cell STING regulates IL6 production and is required for pathological cardiac hypertrophy and contractile dysfunction in experimental heart failure.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00236-6/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00236-6/fulltext
October 2, 2025 at 1:46 PM
Endothelial cell STING regulates IL6 production and is required for pathological cardiac hypertrophy and contractile dysfunction in experimental heart failure.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00236-6/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00236-6/fulltext
#ArticleinPress: The Gut Microbiome as a Possible Mediator in Autoimmunity and Cardiovascular Disease: Shared Pathways and Therapeutic Implications.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00358-X/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00358-X/fulltext
September 29, 2025 at 9:23 PM
#ArticleinPress: The Gut Microbiome as a Possible Mediator in Autoimmunity and Cardiovascular Disease: Shared Pathways and Therapeutic Implications.
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00358-X/fulltext
Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00358-X/fulltext
#LegacyContent: Aurora Kinase A Is Overexpressed in Human Retinoblastoma and Correlates with Histopathologic High-Risk Factors
Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00205-0/fulltext
Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00205-0/fulltext
September 27, 2025 at 4:46 PM
#LegacyContent: Aurora Kinase A Is Overexpressed in Human Retinoblastoma and Correlates with Histopathologic High-Risk Factors
Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00205-0/fulltext
Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00205-0/fulltext
#ArticleinPress: Interplay between Leptin and Stearoyl-CoA Desaturase 1 in Estrogen Receptor-positive Breast Cancer Cells
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00336-0/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00336-0/fulltext
September 26, 2025 at 2:07 PM
#ArticleinPress: Interplay between Leptin and Stearoyl-CoA Desaturase 1 in Estrogen Receptor-positive Breast Cancer Cells
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00336-0/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00336-0/fulltext
#ArticleinPress: Cross-Modality Learning for Predicting IHC Biomarkers from H&E-Stained Whole-Slide Images
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00341-4/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00341-4/fulltext
September 25, 2025 at 7:50 PM
#ArticleinPress: Cross-Modality Learning for Predicting IHC Biomarkers from H&E-Stained Whole-Slide Images
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00341-4/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00341-4/fulltext