Aidan Reynolds (Chemistry Lego Guy)
@aidan-reynolds.bsky.social
27 | B.S Biochemistry | PhD Candidate at Michigan State | Mass Spec Imaging | C. elegans | PFAS Researcher
PhD progress bar: 🟩🟩🟨🟥🟥
PhD progress bar: 🟩🟩🟨🟥🟥
Reposted by Aidan Reynolds (Chemistry Lego Guy)
Isomer-specific distribution of perfluorooctane sulfonate (PFOS) in hepatic zonation in mouse https://www.biorxiv.org/content/10.1101/2025.10.13.682167v1
October 14, 2025 at 10:02 PM
Isomer-specific distribution of perfluorooctane sulfonate (PFOS) in hepatic zonation in mouse https://www.biorxiv.org/content/10.1101/2025.10.13.682167v1
WORM EMERGENCY!!! Our -80 compressor is failing and we’re not sure what will happen to our worm stocks at the current temp (-45C). They’ve been at this temp for 16 hours and we’re contemplating reviving all strains not currently in use to save them, or move them to a new -80. Anyone have advice??
July 9, 2025 at 2:27 PM
WORM EMERGENCY!!! Our -80 compressor is failing and we’re not sure what will happen to our worm stocks at the current temp (-45C). They’ve been at this temp for 16 hours and we’re contemplating reviving all strains not currently in use to save them, or move them to a new -80. Anyone have advice??
That’s me! I’ll be highlighting some cool work with @brukercorporation.bsky.social’s Trapped Ion Mobility Spectrometry (TIMS) showing some neat isomer work during the workshop, and iprm-PASEF data at a poster (WP 266) so come see what myself and my lab are up to!
Hey #TeamMassSpec,
Come join us for the #ASMS2025 Environmental Applications Workshop, Monday afternoon from 5:45-7:00 pm in Rm 349-350. We will have an amazing opening lecture from Susan Richardson, 4 wonderful student speakers, & a quiz (with prizes). See you there! @asms.org
Come join us for the #ASMS2025 Environmental Applications Workshop, Monday afternoon from 5:45-7:00 pm in Rm 349-350. We will have an amazing opening lecture from Susan Richardson, 4 wonderful student speakers, & a quiz (with prizes). See you there! @asms.org
June 1, 2025 at 8:35 PM
That’s me! I’ll be highlighting some cool work with @brukercorporation.bsky.social’s Trapped Ion Mobility Spectrometry (TIMS) showing some neat isomer work during the workshop, and iprm-PASEF data at a poster (WP 266) so come see what myself and my lab are up to!
Finally getting good fluorosmurf assay results since I cut my fluorescein percentage from 2.5% -> 1%. 🪱
March 31, 2025 at 9:35 PM
Finally getting good fluorosmurf assay results since I cut my fluorescein percentage from 2.5% -> 1%. 🪱
Weird question and I fully expect to not get a good answer, but when does the conference date for MAPSS usually get announced? My family wants to visit in late June/July and they go to campgrounds during their stays and they want to book early. I don’t want to tell them a date MAPSS might be on. 😅
February 27, 2025 at 4:35 PM
Weird question and I fully expect to not get a good answer, but when does the conference date for MAPSS usually get announced? My family wants to visit in late June/July and they go to campgrounds during their stays and they want to book early. I don’t want to tell them a date MAPSS might be on. 😅
Reposted by Aidan Reynolds (Chemistry Lego Guy)
Any C. elegans fan?
February 22, 2025 at 7:59 PM
Any C. elegans fan?
Super excited to see someone else try my method for analyzing PFAS using MALDI-TOF with TIMS! I’ve been having great results behind the scenes imaging sulfonates in mouse tissues and it’s awesome to see plant imaging done as well. www.sciencedirect.com/science/arti...
Visualization and spatial mapping of PFAS in the edible storage root of radish
Plants, as key components of trophic networks, play a critical role in the bioaccumulation of PFAS and their transfer to higher trophic levels. This s…
www.sciencedirect.com
February 17, 2025 at 10:05 PM
Super excited to see someone else try my method for analyzing PFAS using MALDI-TOF with TIMS! I’ve been having great results behind the scenes imaging sulfonates in mouse tissues and it’s awesome to see plant imaging done as well. www.sciencedirect.com/science/arti...
Nothing could have prepared me for how tiny microchannel plates are! Got to replace them in an icpTOF S2 and it was awesome. #teammassspec
February 10, 2025 at 10:34 PM
Nothing could have prepared me for how tiny microchannel plates are! Got to replace them in an icpTOF S2 and it was awesome. #teammassspec
Reposted by Aidan Reynolds (Chemistry Lego Guy)
#Celegans #Worms - I'm guessing sending whole labs to big conferences might be too expensive for many labs this year. I want to highlight this meeting will be FREE. VAI will cover all costs and lunch and if people still want night networking I will set something up if enough are interested.
Website and registration for the 11th annual Midwest Worm Meeting on April 18th is now live. Great opportunity for trainees who might not be able to attend the bigger meetings. Also if you'd like to visit VAI or see a great Keynote by Prof. Frank Schroeder this year. - www.vai.org/event/2025-m...
2025 Midwest C. elegans Meeting
Join us for 2025 Midwest C. elegans Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
February 9, 2025 at 7:05 PM
Collaborators didn’t like the manuscript. Redoing a million experiments now. Delayed until March. Feels like the last few months of rushing this paper for grants and fellowship deadlines out were for nothing.
February 5, 2025 at 2:25 AM
Collaborators didn’t like the manuscript. Redoing a million experiments now. Delayed until March. Feels like the last few months of rushing this paper for grants and fellowship deadlines out were for nothing.
This is from my lab! I’m hoping my preprint will be out later this week or Monday! Seems like with grant submissions out of the way we’re finally submitting these papers. 🤣
Dynamics of biofilm-forming Bacillus subtilis in Caenorhabditis elegans gut https://www.biorxiv.org/content/10.1101/2025.01.26.634914v1
January 29, 2025 at 1:58 PM
This is from my lab! I’m hoping my preprint will be out later this week or Monday! Seems like with grant submissions out of the way we’re finally submitting these papers. 🤣
Taking a break from designing lego mass spectrometers and made my stepdad (an electrical engineer who worked in renewable energy) a solar farm. Needed a mental break from submitting a P41 and editing this manuscript. Thank god both of those are done next week.
January 24, 2025 at 12:46 AM
Taking a break from designing lego mass spectrometers and made my stepdad (an electrical engineer who worked in renewable energy) a solar farm. Needed a mental break from submitting a P41 and editing this manuscript. Thank god both of those are done next week.
Unfortunately I can’t go to #Worm2025. I’ll instead be sticking to my midwest roots and going to MAPSS and a midwest C. elegans conference at Van Andel institutute in Grand Rapids, MI.
January 17, 2025 at 4:24 PM
Unfortunately I can’t go to #Worm2025. I’ll instead be sticking to my midwest roots and going to MAPSS and a midwest C. elegans conference at Van Andel institutute in Grand Rapids, MI.
Updating 2 more supplemental figures tomorrow morning and finishing the abstract and conclusion before revising for the next week… so close to being done with this paper 🙏
January 11, 2025 at 1:02 AM
Updating 2 more supplemental figures tomorrow morning and finishing the abstract and conclusion before revising for the next week… so close to being done with this paper 🙏
Pairing microscopy images with my mass spec images… whoof this is tedious when I have 80 images of worms. Going to be a long Sunday for me 🤣
January 5, 2025 at 5:21 PM
Pairing microscopy images with my mass spec images… whoof this is tedious when I have 80 images of worms. Going to be a long Sunday for me 🤣
I need some #Celegans help part people. I have synchronized populations reaching day 1 gravid adulthood and I see differences in length by up to ~100um. Does C. elegans grow a little more once becoming gravid to reach its ~1mm length or… 1/2
January 3, 2025 at 4:51 PM
I need some #Celegans help part people. I have synchronized populations reaching day 1 gravid adulthood and I see differences in length by up to ~100um. Does C. elegans grow a little more once becoming gravid to reach its ~1mm length or… 1/2
Folks I may have just found the Lego parts to make a moveable C. elegans. Stay tuned for a potential build in the coming few days.
January 3, 2025 at 3:17 PM
Folks I may have just found the Lego parts to make a moveable C. elegans. Stay tuned for a potential build in the coming few days.
Ordering a new MCP for the Tofwerk S2 and I’m super excited to get the chance to crack it open and install it with a colleague in the coming weeks. Been awhile since and instrument vendor was chill enough to just send us the SOP and install it ourselves instead of bringing someone out to do it.
January 3, 2025 at 2:33 PM
Ordering a new MCP for the Tofwerk S2 and I’m super excited to get the chance to crack it open and install it with a colleague in the coming weeks. Been awhile since and instrument vendor was chill enough to just send us the SOP and install it ourselves instead of bringing someone out to do it.
Reposted by Aidan Reynolds (Chemistry Lego Guy)
Reposted by Aidan Reynolds (Chemistry Lego Guy)
How hard do bacteria-eating nematodes bite in order to break the bacterial cell wall? Check out our new paper, led by Jason Casar & collab with Jen Dionne, using pressure sensing beads that change color upon compression (bluetorial coming soon) rdcu.be/d5n7v
Upconverting microgauges reveal intraluminal force dynamics in vivo
Nature - Nanoparticle-based ‘microgauges’ are developed for in vivo force sensing and deployed in C. elegans to investigate how mechanical force correlates with electrical signalling in...
rdcu.be
January 1, 2025 at 5:45 PM
How hard do bacteria-eating nematodes bite in order to break the bacterial cell wall? Check out our new paper, led by Jason Casar & collab with Jen Dionne, using pressure sensing beads that change color upon compression (bluetorial coming soon) rdcu.be/d5n7v
2/5 main text figures done (currently doing fig 3), 4/6 supplemental figures done… we’re getting close people!
December 30, 2024 at 8:38 PM
2/5 main text figures done (currently doing fig 3), 4/6 supplemental figures done… we’re getting close people!
I really want to explore career options beyond the USA after I finish my PhD… Canada, Sweden or Australia/New Zealand sound cool. I’m just sick of life here and want to have a comfortable life with my wife doing research.
December 27, 2024 at 7:20 PM
I really want to explore career options beyond the USA after I finish my PhD… Canada, Sweden or Australia/New Zealand sound cool. I’m just sick of life here and want to have a comfortable life with my wife doing research.
I really need to stop publishing around the holidays 🤣
December 25, 2024 at 11:12 PM
I really need to stop publishing around the holidays 🤣
Reposted by Aidan Reynolds (Chemistry Lego Guy)
yep. has happened to me.
December 24, 2024 at 1:53 PM
yep. has happened to me.