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NEJM AI
@ai.nejm.org
NEJM AI, a new monthly journal from the publisher of @nejm.org, explores the cutting-edge applications of artificial intelligence and machine learning in clinical medicine. Online at ai.nejm.org.
𝗖𝗮𝘀𝗲 𝗦𝘁𝘂𝗱𝗶𝗲𝘀
Exploring Large Language Models for Specialist-Level Oncology Care nejm.ai/3LvGAmU

A Case Study of AI-Enabled Software as a Medical Device Cleared by the FDA for Assessing Hemorrhage Risk Index (APPRAISE-HRI) after Trauma nejm.ai/48yUv5p
October 28, 2025 at 5:43 PM
𝗢𝗿𝗶𝗴𝗶𝗻𝗮𝗹 𝗔𝗿𝘁𝗶𝗰𝗹𝗲
A Smartphone-Based Digital Ruler to Automatically Measure Strabismus in Ophthalmologist-Level: A Prospective, Multicenter Cohort Study nejm.ai/43DkcOG
October 28, 2025 at 5:43 PM
Response: Enforceable Safeguards — Verification, Deterrence, and LMIC Agency in Generative AI; A Reply to Rizzo et al. nejm.ai/43FYYzN
October 28, 2025 at 5:43 PM
Response: To the Comment on AI-Assisted Spirometry Interpretation in Primary Care: A Randomized Controlled Trial nejm.ai/47q6nnR

Letter: Generative AI Dual-Use Risks in Infectious Diseases: An Overlooked Challenge for Global Health nejm.ai/4hqJ8yC
October 28, 2025 at 5:43 PM
The Moment AI Arrived in the Clinic: Insights from the SAIL 2025 Year in Review nejm.ai/4hgF5F4

Letter: Comment on “AI-Assisted Spirometry Interpretation in Primary Care: A Randomized Controlled Trial” nejm.ai/4oIXRrs
October 28, 2025 at 5:43 PM
𝗣𝗲𝗿𝘀𝗽𝗲𝗰𝘁𝗶𝘃𝗲𝘀
Advancing the National Academy of Medicine Artificial Intelligence Code of Conduct for Health and Medicine nejm.ai/3Jf0MJ1

Faulty Artificial Intelligence, or the Sleep of Reason nejm.ai/4nV6JKh
October 28, 2025 at 5:43 PM
Letter by Daniel I. Ro, MD: Extending Opportunistic AI Calcium Screening to Noncontrast Head CT for Stroke Risk Stratification nejm.ai/4ntZA3G

Original Article by R. Hagopian et al.: AI Opportunistic Coronary Calcium Screening at Veterans Affairs Hospitals nejm.ai/42YWX1N
October 28, 2025 at 1:35 PM