Annie Handler
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ahandler.bsky.social
Annie Handler
@ahandler.bsky.social
Scientist in biotech | Former postdoc in the Ginty lab @HMS | PhD in the Ruta lab @Rockefeller Univ | Amherst 2012 | she/her
Reposted by Annie Handler
The feeling of a hug comes from the pressure and vibration of millions of nerve endings.
Touch, Our Most Complex Sense, Is a Landscape of Cellular Sensors | Quanta Magazine
Every soft caress of wind, searing burn and seismic rumble is detected by our skin’s tangle of touch sensors. David Ginty has spent his career cataloging the neurons beneath everyday sensations.
www.quantamagazine.org
May 7, 2025 at 8:04 PM
Reposted by Annie Handler
Now would be a good time for university press and communications departments to roll up their sleeves and write and release stories about the breadth and impact of the grant funded science happening at their institutions.
January 28, 2025 at 1:32 PM
Reposted by Annie Handler
Thrilled to share the most recent pub from the Griffith Lab! We show that sodium channels play unique roles in proprioceptive encoding. We also found some really cool effects on skeletal muscle, and a dev dependent role for Nav1.6 in proprioceptive spinal circuits www.science.org/doi/10.1126/...
Differential encoding of mammalian proprioception by voltage-gated sodium channels
Voltage-gated sodium channels differentially encode mammalian proprioception via distinct cellular localization patterns.
www.science.org
January 8, 2025 at 7:49 PM
Reposted by Annie Handler
Check out the impact of the JCC postdoctoral fellowships! Applications open for the next deadline-Jan 31, 2025
December 11, 2024 at 12:09 AM
Reposted by Annie Handler
New: Here's our latest biannual primer on some of the top #biotech trials to watch over the next six months, among them big readouts in Alzheimer's, cancer and heart disease. #biosky

www.biopharmadive.com/news/biotech...
10 clinical trials to watch in the first half of 2025
Expected readouts in diabetes, cancer and depression headline a series of study results that could help the biotechnology sector regain its footing after a shaky year.
www.biopharmadive.com
January 2, 2025 at 11:31 AM
Reposted by Annie Handler
“Wet dog shakes”—a common reflex behavior shared among many hairy mammals and designed to expel water and irritants from their coats—happens when particular mechanoreceptors are activated, researchers studying mice report in Science.

Learn more:
C-LTMRs evoke wet dog shakes via the spinoparabrachial pathway
Many hairy mammals perform rapid oscillations of their body, called wet dog shakes, to remove water and irritants from their back hairy skin. The somatosensory mechanisms that underlie this behavior are unclear. We report that Piezo2-dependent ...
scim.ag
January 1, 2025 at 7:56 PM