Ashling Giblin
@agiblin.bsky.social
Postdoc researching amyloids in ALS and FTD @MRC_LMB @bfalcon lab
• PhD @UCL @UKDRI @adrianisaacslab @IHAatUCL @lindapartridgelab 🧠
• PhD @UCL @UKDRI @adrianisaacslab @IHAatUCL @lindapartridgelab 🧠
Reposted by Ashling Giblin
Every organism's research community aspires to have a resource like FlyBase. Let’s help!
#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 5:35 PM
Every organism's research community aspires to have a resource like FlyBase. Let’s help!
Reposted by Ashling Giblin
Join the UKDRI at UCL in the Salih Lab to explore how glial-specific longevity genes affect ageing and Alzheimer’s, using iPSC models, genomics, and molecular biology @ukdri.ac.uk @dervissalih1.bsky.social Closing date: 26th June
www.dementiaresearcher.nihr.ac.uk/job/research...
www.dementiaresearcher.nihr.ac.uk/job/research...
Research Fellow: Immune system and Cognitive function
Join the UKDRI at UCL in the Salih Lab to explore how glial-specific longevity genes affect ageing & Alzheimer’s using iPSC models, genomics & molecular biology
www.dementiaresearcher.nihr.ac.uk
May 31, 2025 at 9:38 PM
Join the UKDRI at UCL in the Salih Lab to explore how glial-specific longevity genes affect ageing and Alzheimer’s, using iPSC models, genomics, and molecular biology @ukdri.ac.uk @dervissalih1.bsky.social Closing date: 26th June
www.dementiaresearcher.nihr.ac.uk/job/research...
www.dementiaresearcher.nihr.ac.uk/job/research...
Reposted by Ashling Giblin
We tagged C9orf72 repeat dipeptides in patient iPSC-neurons and did genetic and small molecule screens with interesting results! Huge effort from many lab members @ukdri.ac.uk @uclqsion.bsky.social and @alzheimersresearchuk.org Drug Discovery Institute at UCL www.sciencedirect.com/science/arti...
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons
Repeat expansions in C9orf72 are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia. Repeat-associated non-AUG (RAN) t…
www.sciencedirect.com
May 28, 2025 at 2:29 PM
We tagged C9orf72 repeat dipeptides in patient iPSC-neurons and did genetic and small molecule screens with interesting results! Huge effort from many lab members @ukdri.ac.uk @uclqsion.bsky.social and @alzheimersresearchuk.org Drug Discovery Institute at UCL www.sciencedirect.com/science/arti...
Great to see this news and views piece by @sandeepdubey.bsky.social and Hugo Bellen of our recently published work! @alexcammack.bsky.social @adrianisaacs.bsky.social @ukdri.ac.uk @ihaucl.bsky.social www.nature.com/articles/s41...
A neuroprotective role of polyunsaturated fatty acids in C9orf72-ALS/FTD - Nature Neuroscience
New research shows that lipid metabolism genes are downregulated in patient samples and Drosophila models of amyotrophic lateral sclerosis or frontotemporal dementia associated with expansions in C9or...
www.nature.com
March 31, 2025 at 7:54 PM
Great to see this news and views piece by @sandeepdubey.bsky.social and Hugo Bellen of our recently published work! @alexcammack.bsky.social @adrianisaacs.bsky.social @ukdri.ac.uk @ihaucl.bsky.social www.nature.com/articles/s41...
Thank you to Alzheimer's Research UK and the Jean Corsan foundation for this incredible recognition! I am so grateful to ARUK for the continued support throughout my PhD and beyond!
Celebrating excellence! The Jean Corsan & Laura Pulford Prize session highlights outstanding dementia research contributions. Congratulations to all nominees! #ARUKConf25
🏆 Laura Pulford: Felicity Spencer
🏆 Jean Corsan: Ashling Giblin (@agiblin.bsky.social)
🏆 Laura Pulford: Felicity Spencer
🏆 Jean Corsan: Ashling Giblin (@agiblin.bsky.social)
February 26, 2025 at 6:47 PM
Thank you to Alzheimer's Research UK and the Jean Corsan foundation for this incredible recognition! I am so grateful to ARUK for the continued support throughout my PhD and beyond!
Reposted by Ashling Giblin
Really excited this is out! We found polyunsaturated fatty acids (PUFAs) were beneficial in models of C9orf72 FTD/ALS and the greatest benefit occurred when increasing levels specifically within neurons @ukdri.ac.uk @uclqsion.bsky.social @ucl.ac.uk @cziscience.bsky.social
rdcu.be/ebbZf
rdcu.be/ebbZf
Neuronal polyunsaturated fatty acids are protective in ALS/FTD
Nature Neuroscience - Lipidomics revealed that neurons of patients with ALS/FTD have reduced levels of polyunsaturated fatty acid (PUFA)-containing phospholipids. Increasing neuronal PUFA levels...
rdcu.be
February 25, 2025 at 1:31 PM
Really excited this is out! We found polyunsaturated fatty acids (PUFAs) were beneficial in models of C9orf72 FTD/ALS and the greatest benefit occurred when increasing levels specifically within neurons @ukdri.ac.uk @uclqsion.bsky.social @ucl.ac.uk @cziscience.bsky.social
rdcu.be/ebbZf
rdcu.be/ebbZf