Afaf Osman
afafosman.bsky.social
Afaf Osman
@afafosman.bsky.social
Hematologist-scientist at the University of Utah Huntsman Cancer Institute
Love our brilliant genetic counselors
It’s Genetic Counselor Appreciation Day! We’re grateful for our genetic counselors who assess cancer risk, shape personalized screening plans, connect patients with research opportunities and so much more. Their guidance makes a real difference for patients every day.
November 13, 2025 at 6:57 PM
learning about Hepcidin from the legendary Dr. Ganz at our yearly Wintrobe lecture.
September 18, 2025 at 6:16 PM
learning about Hepcidin from the legendary Dr. Ganz at our yearly Wintrobe lecture.
September 18, 2025 at 6:14 PM
Reposted by Afaf Osman
Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans

www.science.org/doi/10.1126/...
Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans
Obesity-associated saturated long-chain fatty acids regulate lung macrophage phenotype and function at steady state and during lung inflammation.
www.science.org
September 13, 2025 at 3:43 PM
Reposted by Afaf Osman
The revised AML relapse model includes 9 predictors, grouped into 3 risk categories that are each associated with distinct OS. buff.ly/woUnuRm #hemesky
August 18, 2025 at 3:15 PM
Reposted by Afaf Osman
A reminder that tens of millions of people are being exposed to dangerous levels of wildfire smoke again this summer.

Wildfire smoke can be up to 10 times more harmful to people than other sources of smog

#wildfire

leahy.substack.com/p/wildfire-s...
Wildfire Smoke: Unsafe In Any Amount
New research reveals the health risks of breathing wildfire smoke
leahy.substack.com
August 4, 2025 at 3:34 PM
Perfect day for a baby’s first real hike! Representing team #myeloid !!!
July 19, 2025 at 3:57 PM
Reposted by Afaf Osman
🧠💉 Curious about how aging affects your blood?
Join Dr. Anna Parks for a fascinating talk on aging and blood clots—what you need to know, what science is discovering, and how it could impact your health.
hemostasistoday.com/insight/nbca...
NBCA Hosts PEP Talk with Dr. Parks on Aging and Blood Clots - Hemostasis Today
NBCA Hosts PEP Talk with Dr. Parks on Aging and Blood Clots / Aging, Anna Parks, Beeson Award, Blood Clots, Hemostasis Today, National Blood Clot Alliance,
hemostasistoday.com
July 19, 2025 at 3:21 PM
Reposted by Afaf Osman
The "iconic and magical" cottonwood trees are the keystone species of the plant world and they're disappearing from Utah riverbanks. Scientists are trying to protect thembut budget freezes by President Trump jeopardizes the work.
Cottonwoods used to line the Colorado River in Utah. What’ll bring the trees back?
The "iconic and magical" cottonwood trees are the keystone species of the plant world and they're disappearing from Utah riverbanks. Scientists are trying to protect thembut budget freezes by President Trump jeopardizes the work.
www.sltrib.com
July 19, 2025 at 3:24 PM
At some point, someone invested in us.

Now it’s our turn.

Join me in supporting the #Fight4Hematology and help secure the future of hematology research and care!

Support the
@ASH_hematology

foundation hematology.org/foundation
ASH Foundation
The ASH Foundation is dedicated to moving hematology forward through charitable support for ASH programs – helping hematologists conquer blood diseases worldwide.
hematology.org
July 17, 2025 at 3:17 AM
Proud to share our paper describing two large Li Fraumeni cohorts with a wide variety of hematologic malignancies, some with surprisingly good outcomes:
Hematologic Malignancy Frequency, Phenotypes, and Outcomes in Li-Fraumeni Syndrome | JCO Precision Oncology ascopubs.org/doi/full/10....
ASCO Publications
ascopubs.org
July 1, 2025 at 8:27 PM
Thinking of the millions who have to withstand this heat with no electricity or air conditioning ..
July 1, 2025 at 4:34 PM
Heartbreaking but he did get to meet his daughter RIP
June 26, 2025 at 2:03 AM
Reposted by Afaf Osman
Practice-changing RCT at #ISTH2025 Late-Breaking Clinical Trial!!!

In acute VTE patients, apixaban therapy led to less clinically-relevant bleeding than rivaroxaban for the first 3 months of therapy. Kudos to Dr Castellucci and colleagues. #COBRRA-VTE
June 22, 2025 at 1:43 PM
Can’t say I didn’t expect #VERONA to be negative but still disappointing. Just had to do a hospice conversation with a patient with high risk #MDS. We desperately need new therapies for this disease.
June 17, 2025 at 7:16 PM
The BEST way to go back to work after maternity leave: the inaugural Western Blood Conference at the beautiful Sundance #wbc2025 @ramgar29b.bsky.social @huntsmancancer.bsky.social
May 28, 2025 at 11:06 PM
Proud of this collaboration with my long time mentor and friend. www.nature.com/articles/s41...
Predisposition to hematopoietic malignancies by deleterious germline CHEK2 variants - Leukemia
Leukemia - Predisposition to hematopoietic malignancies by deleterious germline CHEK2 variants
www.nature.com
May 23, 2025 at 2:33 AM
Reposted by Afaf Osman
Very excited to share that that the Myelomatch study I am leading is open to accrual! We are investigating ASTX727 +/- enasidenib in higher-risk IDH2m MDS

clinicaltrials.gov/study/NCT065...
April 10, 2025 at 8:03 PM
Reposted by Afaf Osman
Mike spotted this before the rest of us. 🫡

Publications from 2025 are shared more on Bluesky than on X/Twitter.
About to talk to medical affairs colleagues, with the news that Bluesky is carrying more posts about new journal publications than X #bluesky #altmetrics #x #xparrot
March 13, 2025 at 3:51 PM
I’m not surprised
Most #PhD scientists in the United States stay in the labor force notably longer than the average person—into their late 60s and in some cases beyond—according to new data from the National Science Foundation. scim.ag/4knpeWn
Why do so many retirement-age scientists keep working?
Survey reveals a desire to hold onto their professional identity keeps Ph.D.s working beyond their 60s
scim.ag
February 28, 2025 at 10:10 PM
Reposted by Afaf Osman
Research-driven advances in cancer science have led to new treatments for the thousands of people diagnosed with rare cancers. Learn more on #RareDiseaseDay: cancerprogressreport.aacr.org/progress/cpr.... #CancerResearchSavesLives® #FundNIH
February 28, 2025 at 5:55 PM
Reposted by Afaf Osman
Actually, not so rare at all!

#RareDiseaseDay

Affecting a substantial part of human kind!

Support research on rare diseases!

Picture from rarediseaseday.org
February 28, 2025 at 7:27 PM
Reposted by Afaf Osman
In 2025, about 1 in 5 cancers diagnosed in the U.S. will be considered rare. Though uncommon individually, rare cancers impact over 400,000 people each year. This weekend, the Beacon of Hope shines in zebra stripes to honor Rare Disease Day and those affected by rare cancers.
February 28, 2025 at 7:26 PM
Today is #rare disease day. Many of the cancers we treat are rare diseases. #NIH and #NCI funding is critical to support research on rare diseases specifically.
February 28, 2025 at 9:23 PM