Ada Lijuan Luo
@adalijuanluo.bsky.social
bioinformatician, microbiologist, Salmonella
Microbes designed by future microbiologists...
March 16, 2024 at 3:54 PM
Microbes designed by future microbiologists...
Reposted by Ada Lijuan Luo
Fascinating story. A reassuring one too, having been challenged earlier this week to explain how lab experiments in simple environments can tell us anything about “real systems”. Well, they reveal the fundamental rules governing how evolution works. (I wish I’d put it like that at the time).
How stable are bacterial genomes as they adapt to an environment? My collaboration with
Anurag Limdi, Alex Couce, @relenski.bsky.social, and
Olivier Tenaillon exploring this over 50,000 generations of evolution is out today! 1/
(cross-post from the other place)
www.science.org/doi/10.1126/...
Anurag Limdi, Alex Couce, @relenski.bsky.social, and
Olivier Tenaillon exploring this over 50,000 generations of evolution is out today! 1/
(cross-post from the other place)
www.science.org/doi/10.1126/...
Changing fitness effects of mutations through long-term bacterial evolution
Predictable and parallel changes occur in the fitness effects of mutations in Escherichia coli over 50,000 generations.
www.science.org
January 27, 2024 at 1:06 PM
Fascinating story. A reassuring one too, having been challenged earlier this week to explain how lab experiments in simple environments can tell us anything about “real systems”. Well, they reveal the fundamental rules governing how evolution works. (I wish I’d put it like that at the time).
Reposted by Ada Lijuan Luo
This is a nice longitudinal metagenomic analysis of CRISPR dynamics in the gut with a lot of cool findings, including showing clearance of MGEs after spacer acquisition:
Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome
www.biorxiv.org/content/10.1...
Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome
www.biorxiv.org/content/10.1...
January 24, 2024 at 4:24 PM
This is a nice longitudinal metagenomic analysis of CRISPR dynamics in the gut with a lot of cool findings, including showing clearance of MGEs after spacer acquisition:
Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome
www.biorxiv.org/content/10.1...
Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome
www.biorxiv.org/content/10.1...