@achyutha-kp.bsky.social
Reposted
Happy to share our lab's recent #cryoEM studies that show how a SPIN90 dimer activates Arp2/3 complex to form either uni or bidirectional actin filaments. Congrats🎉👏 @justusfrancis.bsky.social @achyutha-kp.bsky.social @tejashyamk.bsky.social @sridharskulkarni.bsky.social @kiranvyshnav.bsky.social
New online: Activation of Arp2/3 complex by a SPIN90 dimer in linear actin-filament nucleation
Activation of Arp2/3 complex by a SPIN90 dimer in linear actin-filament nucleation
Nature Structural & Molecular Biology, Published online: 15 September 2025; doi:10.1038/s41594-025-01673-8Francis et al. used cryo-electron microscopy to show how a SPIN90 dimer activates the metazoan Arp2/3 complex to nucleate linear actin filaments for unidirectional and bidirectional growth, forming potential scaffolds for rapid assembly of dynamic actin networks.
go.nature.com
September 15, 2025 at 12:06 PM
Happy to share our lab's recent #cryoEM studies that show how a SPIN90 dimer activates Arp2/3 complex to form either uni or bidirectional actin filaments. Congrats🎉👏 @justusfrancis.bsky.social @achyutha-kp.bsky.social @tejashyamk.bsky.social @sridharskulkarni.bsky.social @kiranvyshnav.bsky.social