Zahin Amin-Chowdhury
@acciochoc.bsky.social
epidemiologist @UKHSA • MSc Epi @lshtm • excited about all things #infectiousdiseases #vaccines #pneumococcus & now #hcai
📊 Mortality
• 30-day case-fatality rate (CFR) fell or stayed stable (except MSSA ↑ 5.2%).
• 30-day mortality rate rose for most infections (in line with incidence rises).
• Graph ⬇️ with data up to 2022/23 shows CFRs across the infections - P. aeruginosa & MRSA among highest CFRs (23-26%)
• 30-day case-fatality rate (CFR) fell or stayed stable (except MSSA ↑ 5.2%).
• 30-day mortality rate rose for most infections (in line with incidence rises).
• Graph ⬇️ with data up to 2022/23 shows CFRs across the infections - P. aeruginosa & MRSA among highest CFRs (23-26%)
September 26, 2025 at 9:46 PM
📊 Mortality
• 30-day case-fatality rate (CFR) fell or stayed stable (except MSSA ↑ 5.2%).
• 30-day mortality rate rose for most infections (in line with incidence rises).
• Graph ⬇️ with data up to 2022/23 shows CFRs across the infections - P. aeruginosa & MRSA among highest CFRs (23-26%)
• 30-day case-fatality rate (CFR) fell or stayed stable (except MSSA ↑ 5.2%).
• 30-day mortality rate rose for most infections (in line with incidence rises).
• Graph ⬇️ with data up to 2022/23 shows CFRs across the infections - P. aeruginosa & MRSA among highest CFRs (23-26%)
MSSA bacteraemia
↗️ Year-on-year increases continue following the pandemic dip (similar to E. coli), reaching ↑ 12% (unlike E. coli) pre-pandemic levels at 24.2 per 100k.
Community-onset cases were the main driver.
↗️ Year-on-year increases continue following the pandemic dip (similar to E. coli), reaching ↑ 12% (unlike E. coli) pre-pandemic levels at 24.2 per 100k.
Community-onset cases were the main driver.
September 26, 2025 at 9:46 PM
MSSA bacteraemia
↗️ Year-on-year increases continue following the pandemic dip (similar to E. coli), reaching ↑ 12% (unlike E. coli) pre-pandemic levels at 24.2 per 100k.
Community-onset cases were the main driver.
↗️ Year-on-year increases continue following the pandemic dip (similar to E. coli), reaching ↑ 12% (unlike E. coli) pre-pandemic levels at 24.2 per 100k.
Community-onset cases were the main driver.
MRSA bacteraemia
⚠️ Sharp ↑ 29.5% to 1.9 per 100k vs 2018/19. Reaching a 12-year high & biggest annual increase since surveillance began. Both hospital- and community-onset driving the rise.
⚠️ Sharp ↑ 29.5% to 1.9 per 100k vs 2018/19. Reaching a 12-year high & biggest annual increase since surveillance began. Both hospital- and community-onset driving the rise.
September 26, 2025 at 9:46 PM
MRSA bacteraemia
⚠️ Sharp ↑ 29.5% to 1.9 per 100k vs 2018/19. Reaching a 12-year high & biggest annual increase since surveillance began. Both hospital- and community-onset driving the rise.
⚠️ Sharp ↑ 29.5% to 1.9 per 100k vs 2018/19. Reaching a 12-year high & biggest annual increase since surveillance began. Both hospital- and community-onset driving the rise.
Pseudomonas aeruginosa bacteraemia
↔️ Incidence has mostly remained steady → 7.8 per 100k in 2024/25.
🏥 Hospital-onset incidence = 4.8 per 100k bed-days.
↔️ Incidence has mostly remained steady → 7.8 per 100k in 2024/25.
🏥 Hospital-onset incidence = 4.8 per 100k bed-days.
September 26, 2025 at 9:46 PM
Pseudomonas aeruginosa bacteraemia
↔️ Incidence has mostly remained steady → 7.8 per 100k in 2024/25.
🏥 Hospital-onset incidence = 4.8 per 100k bed-days.
↔️ Incidence has mostly remained steady → 7.8 per 100k in 2024/25.
🏥 Hospital-onset incidence = 4.8 per 100k bed-days.
Klebsiella spp. bacteraemia
↗️ Last year saw the sharpest increase since surveillance began - ↑ 10.3%.
Incidence rose again this year to 23.6 per 100k (+2.9% vs 2023/24).
Largely driven by community-onset infections. While most age-sex groups saw rise, particularly notable among male 75+ years.
↗️ Last year saw the sharpest increase since surveillance began - ↑ 10.3%.
Incidence rose again this year to 23.6 per 100k (+2.9% vs 2023/24).
Largely driven by community-onset infections. While most age-sex groups saw rise, particularly notable among male 75+ years.
September 26, 2025 at 9:46 PM
Klebsiella spp. bacteraemia
↗️ Last year saw the sharpest increase since surveillance began - ↑ 10.3%.
Incidence rose again this year to 23.6 per 100k (+2.9% vs 2023/24).
Largely driven by community-onset infections. While most age-sex groups saw rise, particularly notable among male 75+ years.
↗️ Last year saw the sharpest increase since surveillance began - ↑ 10.3%.
Incidence rose again this year to 23.6 per 100k (+2.9% vs 2023/24).
Largely driven by community-onset infections. While most age-sex groups saw rise, particularly notable among male 75+ years.
E. coli bacteraemia
⤴️ In 2024/25, cases rose 17% since 2020/21 → 76.6 per 100k. This rise follows the COVID-19 pandemic dip and is now back to levels similar to those seen in 2018/19.
Most (81%) remain community-onset.
⤴️ In 2024/25, cases rose 17% since 2020/21 → 76.6 per 100k. This rise follows the COVID-19 pandemic dip and is now back to levels similar to those seen in 2018/19.
Most (81%) remain community-onset.
September 26, 2025 at 9:46 PM
E. coli bacteraemia
⤴️ In 2024/25, cases rose 17% since 2020/21 → 76.6 per 100k. This rise follows the COVID-19 pandemic dip and is now back to levels similar to those seen in 2018/19.
Most (81%) remain community-onset.
⤴️ In 2024/25, cases rose 17% since 2020/21 → 76.6 per 100k. This rise follows the COVID-19 pandemic dip and is now back to levels similar to those seen in 2018/19.
Most (81%) remain community-onset.