Alex Bradu
@abradu.bsky.social
uchicago ‘23 | nyc | satija lab RA | she/her 🧬 👩🏻🔬🔬
Reposted by Alex Bradu
Nature research paper: Thymic epithelial cells amplify epigenetic noise to promote immune tolerance
go.nature.com/41TUQLE
go.nature.com/41TUQLE
Thymic epithelial cells amplify epigenetic noise to promote immune tolerance - Nature
The activity of the tumour-suppressor protein p53 is repressed in the thymus to augment fluctuations in background chromatin accessibility as a means of mediating ectopic gene expression and immune tolerance.
go.nature.com
August 25, 2025 at 5:42 PM
Nature research paper: Thymic epithelial cells amplify epigenetic noise to promote immune tolerance
go.nature.com/41TUQLE
go.nature.com/41TUQLE