Aaron Storey
@aaronstorey.bsky.social
Mass Spectrometry Core Director at Arkana Laboratories
Isotopically labeled internal standard peptides are unreasonably effective at establishing analytical measuring ranges for peptides liberated from tryptic digests. It’s unfortunate that IS panels are so expensive, otherwise more scientists would use internal standards to ground their measurements.
July 10, 2025 at 2:27 AM
Isotopically labeled internal standard peptides are unreasonably effective at establishing analytical measuring ranges for peptides liberated from tryptic digests. It’s unfortunate that IS panels are so expensive, otherwise more scientists would use internal standards to ground their measurements.
Reposted by Aaron Storey
Andy Hoofnagle and I wrote a comment about the paper also in Clin Chem pubmed.ncbi.nlm.nih.gov/40272410/
The Need for Better Validation: Evaluating Aptamer and Proximity Extension Assays for Large-Scale Clinical Proteomics Studies - PubMed
The Need for Better Validation: Evaluating Aptamer and Proximity Extension Assays for Large-Scale Clinical Proteomics Studies
pubmed.ncbi.nlm.nih.gov
April 28, 2025 at 4:54 PM
Andy Hoofnagle and I wrote a comment about the paper also in Clin Chem pubmed.ncbi.nlm.nih.gov/40272410/
From the article: “Laboratory testing for this antigen [NDNF] by immunostaining or mass spectrometry can help identify cases of MN that are secondary to syphilis, prompting treatment with penicillin, which has shown to be effective in patients with both primary and secondary syphilis.”
April 3, 2025 at 9:12 AM
From the article: “Laboratory testing for this antigen [NDNF] by immunostaining or mass spectrometry can help identify cases of MN that are secondary to syphilis, prompting treatment with penicillin, which has shown to be effective in patients with both primary and secondary syphilis.”