Aaron Mercer
@a-mercer.bsky.social
Senior Principal Scientist @boehringerglobal.bsky.social 🔬 / distance runner https://www.strava.com/athletes/2258146 ⚡/ dog wrangler // view are my own
Pinned
Reposted by Aaron Mercer
In a new @fralinbiomed.bsky.social study, 18- to 21-year-olds put on to a diet high in ultra-processed foods were more likely to overeat — even when full.
⬇️🔬Learn more.
⬇️🔬Learn more.
All you can eat: Ultra-processed foods affect young adults differently
In a new study, 18- to 21-year-olds put on to a diet high in ultra-processed foods were more likely to overeat — even when full.
news.vt.edu
November 24, 2025 at 2:16 PM
In a new @fralinbiomed.bsky.social study, 18- to 21-year-olds put on to a diet high in ultra-processed foods were more likely to overeat — even when full.
⬇️🔬Learn more.
⬇️🔬Learn more.
Reposted by Aaron Mercer
About that exclusive, "closed-to-press" MAHA summit last week with RFK and JD Vance: I got in.
Here's what I saw. 🧵 🧪
www.nature.com/articles/d41...
Here's what I saw. 🧵 🧪
www.nature.com/articles/d41...
November 21, 2025 at 5:01 PM
About that exclusive, "closed-to-press" MAHA summit last week with RFK and JD Vance: I got in.
Here's what I saw. 🧵 🧪
www.nature.com/articles/d41...
Here's what I saw. 🧵 🧪
www.nature.com/articles/d41...
Reposted by Aaron Mercer
It's weird. A hundred years ago, only rich people owned cars while everyone else owned horses. Now only rich people own horses while everyone else owns cars.
How the stables have turned.
How the stables have turned.
November 8, 2025 at 7:14 PM
It's weird. A hundred years ago, only rich people owned cars while everyone else owned horses. Now only rich people own horses while everyone else owns cars.
How the stables have turned.
How the stables have turned.
Industry postdoc opening! My sister dept @ @boehringerglobal.bsky.social Germany (Obesity Research area) is seeking a post-PhD candidate with significant technical expertise in brain ephys & imaging. Feel free to DM me with any further questions.
Post Doc - Electrophysiology & Sensor imaging of brain-obesity circuits
Post Doc - Electrophysiology & Sensor imaging of brain-obesity circuits
jobs.boehringer-ingelheim.com
October 30, 2025 at 2:50 PM
Industry postdoc opening! My sister dept @ @boehringerglobal.bsky.social Germany (Obesity Research area) is seeking a post-PhD candidate with significant technical expertise in brain ephys & imaging. Feel free to DM me with any further questions.
Reposted by Aaron Mercer
I don't think that microdosing a GLP-1 will achieve the first endpoint in this ad, nor do I believe any of the other "outcomes" have been validated in in a fully randomized, placebo-controlled study.
"It's Clinical"
No it isn't. There are no published data for this.
Full page ad in NY Times today
No it isn't. There are no published data for this.
Full page ad in NY Times today
October 28, 2025 at 1:45 PM
I don't think that microdosing a GLP-1 will achieve the first endpoint in this ad, nor do I believe any of the other "outcomes" have been validated in in a fully randomized, placebo-controlled study.
Reposted by Aaron Mercer
On NAD+ supplement: "The science is almost nonexistent."
www.nytimes.com/2025/10/23/w...
www.nytimes.com/2025/10/23/w...
Longevity Seekers Are Taking N.A.D.+ Supplements. Do They Work?
www.nytimes.com
October 28, 2025 at 10:55 AM
On NAD+ supplement: "The science is almost nonexistent."
www.nytimes.com/2025/10/23/w...
www.nytimes.com/2025/10/23/w...
Reposted by Aaron Mercer
Just before everything turns brown for 5 months.
October 23, 2025 at 12:25 PM
Just before everything turns brown for 5 months.
Reposted by Aaron Mercer
Visceral adipose tissue acts as an endocrine organ that is involved in pathophysiological signalling affecting several organ systems, which contributes to the development of #MetabolicSyndrome https://www.nature.c...
October 22, 2025 at 6:50 AM
Visceral adipose tissue acts as an endocrine organ that is involved in pathophysiological signalling affecting several organ systems, which contributes to the development of #MetabolicSyndrome https://www.nature.c...
Reposted by Aaron Mercer
Inaugural bluesky post to say the AWS outage has me thinking about @timmaughan.bsky.social and Infinite Detail even more than normal lol. Feel like every other week something happens that gives me a reason to recommend your book dude
October 21, 2025 at 12:37 PM
Inaugural bluesky post to say the AWS outage has me thinking about @timmaughan.bsky.social and Infinite Detail even more than normal lol. Feel like every other week something happens that gives me a reason to recommend your book dude
calnewport.com/is-sora-the-...
If anything, I'm spending more time offline due to the growing mess of AI slop. Not a bug, but a feature?
If anything, I'm spending more time offline due to the growing mess of AI slop. Not a bug, but a feature?
Is Sora the Beginning of the End for OpenAI? - Cal Newport
On my podcast this week, I took a closer look at OpenAI’s new video generation model, Sora 2, which can turn simple text descriptions into ... Read more
calnewport.com
October 20, 2025 at 6:24 PM
calnewport.com/is-sora-the-...
If anything, I'm spending more time offline due to the growing mess of AI slop. Not a bug, but a feature?
If anything, I'm spending more time offline due to the growing mess of AI slop. Not a bug, but a feature?
Pre-Nor'easter fall vibes with Samson #eastcoast #beastcoast
October 13, 2025 at 4:08 PM
Pre-Nor'easter fall vibes with Samson #eastcoast #beastcoast
Reposted by Aaron Mercer
Oh, the “vomiting ferret” model is absolutely a real thing - I’ve encountered it in my own drug discovery career.
They’re one of the smallest animals that show this response- weirdly, rodents can’t do it at all.
They’re one of the smallest animals that show this response- weirdly, rodents can’t do it at all.
October 8, 2025 at 12:06 PM
Oh, the “vomiting ferret” model is absolutely a real thing - I’ve encountered it in my own drug discovery career.
They’re one of the smallest animals that show this response- weirdly, rodents can’t do it at all.
They’re one of the smallest animals that show this response- weirdly, rodents can’t do it at all.
Living his best life. Amazing.
Fred Ramsdell was parked at a campground in Montana on Monday when his wife suddenly started shouting. He first thought that maybe she had seen a grizzly bear. Instead, she had regained cell service and had seen a flood of text messages with the same news. “You just won the Nobel Prize!” she yelled.
Winning a Nobel Prize Interrupted His Off-the-Grid Vacation
Fred Ramsdell found out about his Nobel Prize nearly 12 hours after it was announced because he was on vacation in the Rockies.
nyti.ms
October 8, 2025 at 12:38 PM
Living his best life. Amazing.
Reposted by Aaron Mercer
Why do optical illusions work? The culprit may be a group of neurons in the visual cortex that help us fill in missing information.
@markjohnpost.bsky.social for @washingtonpost.com dives into the science and how it could help demystify visual hallucinations: www.washingtonpost.com/science/2025...
@markjohnpost.bsky.social for @washingtonpost.com dives into the science and how it could help demystify visual hallucinations: www.washingtonpost.com/science/2025...
The origins of hallucinations are traced in specialized brain cells
Researchers used lasers to record and stimulate the activity of neurons in mice to learn how the brain processes and interprets optical illusions.
www.washingtonpost.com
October 6, 2025 at 10:06 PM
Why do optical illusions work? The culprit may be a group of neurons in the visual cortex that help us fill in missing information.
@markjohnpost.bsky.social for @washingtonpost.com dives into the science and how it could help demystify visual hallucinations: www.washingtonpost.com/science/2025...
@markjohnpost.bsky.social for @washingtonpost.com dives into the science and how it could help demystify visual hallucinations: www.washingtonpost.com/science/2025...
Reposted by Aaron Mercer
60 seconds of therapy
October 5, 2025 at 5:03 PM
60 seconds of therapy
Despite the lack of recent rain, there sure are plenty of amphibians around my property #herpetology #moss
October 6, 2025 at 1:04 AM
Despite the lack of recent rain, there sure are plenty of amphibians around my property #herpetology #moss
Reposted by Aaron Mercer
quick while the government is shut down let’s all switch to metric
October 1, 2025 at 4:11 AM
quick while the government is shut down let’s all switch to metric
Kind of weird that bluesky has a specific feed dedicated to #moss (and the outdoors), but I'm here for it. Here are some of the latest from my little 2-acre plot in the woods.
October 1, 2025 at 4:44 PM
Kind of weird that bluesky has a specific feed dedicated to #moss (and the outdoors), but I'm here for it. Here are some of the latest from my little 2-acre plot in the woods.
Reposted by Aaron Mercer
We have developed a new workflow to map in 3D at single-cell resolution whole human organs.
Prof. Rong Fan (Yale) mapped out immune cell populations in the vicinity of ovarian precancerous lesions in healthy women and found no enrichment.
More here: www.biorxiv.org/content/10.1...
Prof. Rong Fan (Yale) mapped out immune cell populations in the vicinity of ovarian precancerous lesions in healthy women and found no enrichment.
More here: www.biorxiv.org/content/10.1...
October 1, 2025 at 12:42 PM
We have developed a new workflow to map in 3D at single-cell resolution whole human organs.
Prof. Rong Fan (Yale) mapped out immune cell populations in the vicinity of ovarian precancerous lesions in healthy women and found no enrichment.
More here: www.biorxiv.org/content/10.1...
Prof. Rong Fan (Yale) mapped out immune cell populations in the vicinity of ovarian precancerous lesions in healthy women and found no enrichment.
More here: www.biorxiv.org/content/10.1...
Reposted by Aaron Mercer
Even though I've spent most of my career focused on obesity, I'll be at @americanheart.bsky.social in NOLA in early November as my research group at @boehringerglobal.bsky.social builds up our cardiorenal focus. See you there!
September 25, 2025 at 6:11 PM
Even though I've spent most of my career focused on obesity, I'll be at @americanheart.bsky.social in NOLA in early November as my research group at @boehringerglobal.bsky.social builds up our cardiorenal focus. See you there!
That title is a mouthful 😆 Congrats to Darleen, @seeleyrj.bsky.social, @henningfenselau.bsky.social and team. www.sciencedirect.com/science/arti...
Weight Loss Reverses Obesity-Associated Impairments in Acute Gastrointestinal Stretch-Induced Suppression of Food Intake and Glucose Homeostasis
www.sciencedirect.com
September 25, 2025 at 6:09 PM
That title is a mouthful 😆 Congrats to Darleen, @seeleyrj.bsky.social, @henningfenselau.bsky.social and team. www.sciencedirect.com/science/arti...