Alia dos Santos
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a-dsantos.bsky.social
Alia dos Santos
@a-dsantos.bsky.social
Wellcome ECA fellow; Investigator Scientist
MRC Laboratory of Molecular Biology

Studying nuclear envelope repair and nuclear reshaping during cell differentiation and spermatogenesis

Reposted by Alia dos Santos
Ever wondered how the chemotherapeutic drug paclitaxel can target slow-dividing tumours? Check out our preprint Hale et al! @tom-hale.bsky.social found a novel non-mitotic mechanism of action for paclitaxel involving nuclear-cytoskeletal coupling via the LINC complex!
www.biorxiv.org/content/10.1...
January 20, 2025 at 2:47 PM
Reposted by Alia dos Santos
Ever wondered if nuclear pore architecture and function changes during germ cell differentiation? In human spermatogenesis it does, and radically!!
Check out our first lab preprint @AliaCSantos et al! www.biorxiv.org/content/10.1...
November 1, 2024 at 12:34 PM