Athanasios Alexandris, MBChB
@a-alexandris.bsky.social
#Neuroscientist, #Physician - #Axons, #Neurodegeneration, #TBI. 🧠 Research Associate. @JohnsHopkins @JHUPath. (He/him)
In our new study (doi.org/10.1093/jnen...), we map high-resolution changes in the visual system in the EAE model of MS. Early deficits in axonal transport and function occur before overt axon or RGC loss, highlighting a window for axon-targeted neuroprotection in demyelinating disease. 1/5
Temporal progression of axonal degeneration in the visual system in experimental autoimmune encephalomyelitis: Insights from high-resolution neuropathology
Abstract. Multiple sclerosis (MS) is characterized by inflammation, demyelination, and axonal degeneration in the CNS, leading to progressive neurological
doi.org
July 3, 2025 at 5:50 PM
In our new study (doi.org/10.1093/jnen...), we map high-resolution changes in the visual system in the EAE model of MS. Early deficits in axonal transport and function occur before overt axon or RGC loss, highlighting a window for axon-targeted neuroprotection in demyelinating disease. 1/5
Reposted by Athanasios Alexandris, MBChB
Our new paper is out! Even with helmet protection, high-energy blunt trauma can lead to fatal respiratory failure. Our study maps specific brainstem injury patterns, revealing critical implications for #TBI & protection. Patterns of #vascularinjury ≠ #axonalinjury www.liebertpub.com/doi/10.1089/...
Diffuse Axonal and Vascular Pathology in the Gyrencephalic Brain after High-Energy Blunt Injury: Clinicopathological Correlations Involving the Brainstem | Journal of Neurotrauma
Traumatic brain injury (TBI) after high-energy, behind helmet blunt trauma (BHBT) is an important but poorly understood clinical entity often associated with apnea and death in humans. In this study, ...
www.liebertpub.com
December 31, 2024 at 7:37 PM
Our new paper is out! Even with helmet protection, high-energy blunt trauma can lead to fatal respiratory failure. Our study maps specific brainstem injury patterns, revealing critical implications for #TBI & protection. Patterns of #vascularinjury ≠ #axonalinjury www.liebertpub.com/doi/10.1089/...