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New human inborn error of immunity.
We describe the first reported human with a monogenic disorder caused by the disruption of ZBTB7B, which encodes the transcription factor ThPOK.
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@ubcmedicine.bsky.social @bcchresearch.bsky.social
New human inborn error of immunity.
We describe the first reported human with a monogenic disorder caused by the disruption of ZBTB7B, which encodes the transcription factor ThPOK.
rupress.org/jem/article/...
@ubcmedicine.bsky.social @bcchresearch.bsky.social
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The cover image represents the confocal imaging of periportal-venous fibroblasts in the liver of 8-wk-old Cd34creER;R26tdTomato mice. Fibroblasts are marked by CD34 (green) and Tomato (red). From Shan-Shan Wang et al.: doi.org/10.1084/jem....
The cover image represents the confocal imaging of periportal-venous fibroblasts in the liver of 8-wk-old Cd34creER;R26tdTomato mice. Fibroblasts are marked by CD34 (green) and Tomato (red). From Shan-Shan Wang et al.: doi.org/10.1084/jem....
Radiotherapy induces GM-CSF in melanoma, driving monocytes to become regulatory monocyte-derived dendritic cells (moDCs)—traced with Ms4a3-TdTomato mice!
Huge shoutout to @Sirimuvva Tadepalli + @Derek Clements for leading this!
Radiotherapy induces GM-CSF in melanoma, driving monocytes to become regulatory monocyte-derived dendritic cells (moDCs)—traced with Ms4a3-TdTomato mice!
Huge shoutout to @Sirimuvva Tadepalli + @Derek Clements for leading this!
#InfectiousDisease #HostDefense #LymphocyteBiology
#InfectiousDisease #HostDefense #LymphocyteBiology