Zechuan Shi
@zechuanshi.bsky.social
Bioinformatics Ph.D. Candidate @Swarup Lab @UCIrvine
🚨 Our new paper is out on Science Advances @science.org! We mapped single-cell regulatory landscapes in Alzheimer’s (AD) and Pick’s disease (PiD) to uncover how distinct enhancer and TF programs shape disease-specific vulnerability.
www.science.org/doi/10.1126/...
#ScienceAdvances
www.science.org/doi/10.1126/...
#ScienceAdvances
Single-nucleus multi-omics identifies shared and distinct pathways in Pick’s and Alzheimer’s disease
Comparative studies in AD and PiD reveal critical regulatory changes and identify risk gene associations for PiD.
www.science.org
November 17, 2025 at 6:33 PM
🚨 Our new paper is out on Science Advances @science.org! We mapped single-cell regulatory landscapes in Alzheimer’s (AD) and Pick’s disease (PiD) to uncover how distinct enhancer and TF programs shape disease-specific vulnerability.
www.science.org/doi/10.1126/...
#ScienceAdvances
www.science.org/doi/10.1126/...
#ScienceAdvances