Syed Zawar Shah
@zawarshah.bsky.social
Ph.D. in Vannini lab @HumanTechnopole
Pinned
🔬Our @zawarshah.bsky.social with the @alessandrovannini.bsky.social group reveal how the molecular complex SNAPc acts as a "dual recruiter" for RNA Polymerase II & III, advancing our understanding of RNA transcription.
📰 Published in @naturecomms.bsky.social humantechnopole.it/en/news/how-...
📰 Published in @naturecomms.bsky.social humantechnopole.it/en/news/how-...
How SNAPc recruits human RNA polymerases at snRNA genes - Human Technopole
Using advanced cryo-electron microscopy and cross-linking mass spectrometry, HT researchers provide unprecedented insight into how SNAPc works as a "dual recruiter" for RNA Polymerase II and III. The ...
humantechnopole.it
🙌
Reposted by Syed Zawar Shah
Reposted by Syed Zawar Shah
New discovery from our #CDlab reported in Cell @cp-cell.bsky.social today:
SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion!
www.sciencedirect.com/science/arti...
1/
SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion!
www.sciencedirect.com/science/arti...
1/
January 16, 2025 at 4:11 PM
New discovery from our #CDlab reported in Cell @cp-cell.bsky.social today:
SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion!
www.sciencedirect.com/science/arti...
1/
SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion!
www.sciencedirect.com/science/arti...
1/
🙌
🔬Our @zawarshah.bsky.social with the @alessandrovannini.bsky.social group reveal how the molecular complex SNAPc acts as a "dual recruiter" for RNA Polymerase II & III, advancing our understanding of RNA transcription.
📰 Published in @naturecomms.bsky.social humantechnopole.it/en/news/how-...
📰 Published in @naturecomms.bsky.social humantechnopole.it/en/news/how-...
How SNAPc recruits human RNA polymerases at snRNA genes - Human Technopole
Using advanced cryo-electron microscopy and cross-linking mass spectrometry, HT researchers provide unprecedented insight into how SNAPc works as a "dual recruiter" for RNA Polymerase II and III. The ...
humantechnopole.it
January 9, 2025 at 4:54 PM
🙌
Reposted by Syed Zawar Shah
Excited to share the (hard) work of @zawarshah.bsky.social in its final form: www.nature.com/articles/s41...
A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work
A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work
Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters - Nature Communications
The snRNA Activating Protein Complex (SNAPc) mediates snRNA transcription by RNA Pol II and III. Here, the authors have used cryo-EM to resolve the structure of the SNAPc-bound RNA Pol III pre-initiat...
www.nature.com
January 3, 2025 at 10:37 AM
Excited to share the (hard) work of @zawarshah.bsky.social in its final form: www.nature.com/articles/s41...
A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work
A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work
Reposted by Syed Zawar Shah
Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology
Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...
www.nature.com
November 18, 2024 at 11:06 AM
Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps.
www.nature.com/articles/s41...
www.nature.com/articles/s41...