We make molecules!
@wemakemolecules.bsky.social
The Yeast Natural Products lab, we love fungi and chemistry.
Reposted by We make molecules!
Read the associated news and views:
Microbial chocolatiers of fine flavour 🍫
by Pablo Cruz-Morales
www.nature.com/articles/s41...
Microbial chocolatiers of fine flavour 🍫
by Pablo Cruz-Morales
www.nature.com/articles/s41...
August 18, 2025 at 3:37 PM
Read the associated news and views:
Microbial chocolatiers of fine flavour 🍫
by Pablo Cruz-Morales
www.nature.com/articles/s41...
Microbial chocolatiers of fine flavour 🍫
by Pablo Cruz-Morales
www.nature.com/articles/s41...
Climate change is stressing our forests, fungal allies may turn into pathogens. Are we ready for this?
Don’t miss this call to action for new model organisms & functional studies in forest pathogens. By Anne Oostlander and col. at TU Braunschweig and FABI
nph.onlinelibrary.wiley.com/doi/full/10....
Don’t miss this call to action for new model organisms & functional studies in forest pathogens. By Anne Oostlander and col. at TU Braunschweig and FABI
nph.onlinelibrary.wiley.com/doi/full/10....
May 12, 2025 at 2:21 PM
Climate change is stressing our forests, fungal allies may turn into pathogens. Are we ready for this?
Don’t miss this call to action for new model organisms & functional studies in forest pathogens. By Anne Oostlander and col. at TU Braunschweig and FABI
nph.onlinelibrary.wiley.com/doi/full/10....
Don’t miss this call to action for new model organisms & functional studies in forest pathogens. By Anne Oostlander and col. at TU Braunschweig and FABI
nph.onlinelibrary.wiley.com/doi/full/10....
Our biosynthetic survey of biocontrol fungi is out now!
lnkd.in/dJbyis5f
Dr. Ana Calheiros de Carvalho combined analytical chemistry, post-genomics and Synbio to catalog and discover lots of natural products. Data release in the next few days:
Check our preprint for details ⚗️ 🍄 🥰 🌽
lnkd.in/dJbyis5f
Dr. Ana Calheiros de Carvalho combined analytical chemistry, post-genomics and Synbio to catalog and discover lots of natural products. Data release in the next few days:
Check our preprint for details ⚗️ 🍄 🥰 🌽
March 10, 2025 at 10:26 AM
Our biosynthetic survey of biocontrol fungi is out now!
lnkd.in/dJbyis5f
Dr. Ana Calheiros de Carvalho combined analytical chemistry, post-genomics and Synbio to catalog and discover lots of natural products. Data release in the next few days:
Check our preprint for details ⚗️ 🍄 🥰 🌽
lnkd.in/dJbyis5f
Dr. Ana Calheiros de Carvalho combined analytical chemistry, post-genomics and Synbio to catalog and discover lots of natural products. Data release in the next few days:
Check our preprint for details ⚗️ 🍄 🥰 🌽
Our PhD student Adrian Gadar López and the Black Yeast Natural Products team made fungal PKS Heterologous Expression easy! Check out the preprint.
www.researchsquare.com/article/rs-6...
#wemakemolecules #blackyeast #NNF_BRIGHT
www.researchsquare.com/article/rs-6...
#wemakemolecules #blackyeast #NNF_BRIGHT
Black yeasts are efficient heterologous hosts of a wide range of fungal polyketides
Fungal natural products, including polyketides, are a rich source of bioactive molecules. Their biosynthetic enzymes are encoded within biosynthetic gene clusters, which are often activated by specifi...
www.researchsquare.com
February 20, 2025 at 4:06 PM
Our PhD student Adrian Gadar López and the Black Yeast Natural Products team made fungal PKS Heterologous Expression easy! Check out the preprint.
www.researchsquare.com/article/rs-6...
#wemakemolecules #blackyeast #NNF_BRIGHT
www.researchsquare.com/article/rs-6...
#wemakemolecules #blackyeast #NNF_BRIGHT
Reposted by We make molecules!
getphylo is finally official! Build phylogenetic trees directly from genbank files - at breakneck speed! I'd like to thank everyone who provided feedback and encourage you to continue. Improving getphylo doesn't stop now the paper is out!
1/5
🧪
bmcbioinformatics.biomedcentral.com/articles/10....
1/5
🧪
bmcbioinformatics.biomedcentral.com/articles/10....
getphylo: rapid and automatic generation of multi-locus phylogenetic trees - BMC Bioinformatics
Background The increasing amount of genomic data calls for tools that can create genome-scale phylogenies quickly and efficiently. Existing tools rely on large reference databases or require lengthy d...
bmcbioinformatics.biomedcentral.com
January 22, 2025 at 11:31 AM
getphylo is finally official! Build phylogenetic trees directly from genbank files - at breakneck speed! I'd like to thank everyone who provided feedback and encourage you to continue. Improving getphylo doesn't stop now the paper is out!
1/5
🧪
bmcbioinformatics.biomedcentral.com/articles/10....
1/5
🧪
bmcbioinformatics.biomedcentral.com/articles/10....
Reposted by We make molecules!
Have a look at our latest study on large-scale #Streptomyces BGC mining / pangenome analysis: genomebiology.biomedcentral.com/articles/10....
January 15, 2025 at 1:01 PM
Have a look at our latest study on large-scale #Streptomyces BGC mining / pangenome analysis: genomebiology.biomedcentral.com/articles/10....
Feeding 9 billion people will take lots of creativity and the best scientists. Check how Dr. Loes van Dam is working on new fungal foods are DTU biosustain. #DTU_BRIGHT
www.euronews.com/health/2025/...
www.euronews.com/health/2025/...
Fungi oysters: Inside the Danish lab producing next alternative food
At a Technical University of Denmark lab, researchers are exploring the potential for fungi to be used as meat and seafood replacements.
www.euronews.com
January 9, 2025 at 1:40 AM
Feeding 9 billion people will take lots of creativity and the best scientists. Check how Dr. Loes van Dam is working on new fungal foods are DTU biosustain. #DTU_BRIGHT
www.euronews.com/health/2025/...
www.euronews.com/health/2025/...
Reposted by We make molecules!
Are you working with #streptomycetes? Then you may be interested in trying our new #StreptoCAD platform: StreptoCAD is an open-source software
toolbox automating genome engineering
workflows in streptomycetes. www.biorxiv.org/content/10.1...
toolbox automating genome engineering
workflows in streptomycetes. www.biorxiv.org/content/10.1...
StreptoCAD: An open-source software toolbox automating genome engineering workflows in streptomycetes
Streptomycetes hold immense potential for discovering novel bioactive molecules for applications in medicine or sustainable agriculture. However, high-throughput exploration is hampered by the current...
www.biorxiv.org
January 7, 2025 at 2:16 PM
Are you working with #streptomycetes? Then you may be interested in trying our new #StreptoCAD platform: StreptoCAD is an open-source software
toolbox automating genome engineering
workflows in streptomycetes. www.biorxiv.org/content/10.1...
toolbox automating genome engineering
workflows in streptomycetes. www.biorxiv.org/content/10.1...
Diplodia sapinea a pine endophyte lives a harmless life until the tree is dying... Climate change is stressing trees and turning harmless fungi into pathogens. How? It is not clear, new tools to study them are needed, check work by Anne Oostlander of TU Braunschweig journals.plos.org/plosone/arti...
Development of a molecular genetics and cell biology toolbox for the filamentous fungus Diplodia sapinea
Diplodia sapinea (Fr.) Fuckel is a widespread fungal pathogen affecting conifers worldwide. Infections can lead to severe symptoms, such as shoot blight, canker, tree death, or blue stain in harvested...
journals.plos.org
January 7, 2025 at 4:11 PM
Diplodia sapinea a pine endophyte lives a harmless life until the tree is dying... Climate change is stressing trees and turning harmless fungi into pathogens. How? It is not clear, new tools to study them are needed, check work by Anne Oostlander of TU Braunschweig journals.plos.org/plosone/arti...
The perfect molecule doesn't exist... Until Dr Ana Calheiros de Carvalho find it with her metabologenomics workflow for biocontrol molecules! Check it out poster #81 #NP2025 San Diego #DTU_BRIGHT
January 7, 2025 at 4:45 AM
The perfect molecule doesn't exist... Until Dr Ana Calheiros de Carvalho find it with her metabologenomics workflow for biocontrol molecules! Check it out poster #81 #NP2025 San Diego #DTU_BRIGHT
N.R.P.S. will stand for No Resistant Pest will Stand after Dr Carolina Cano-Prieto engineer them with her SynBio tools. Poster 38 #NP2025 #DTU_BRIGHT #sustainableagriculture
January 7, 2025 at 4:31 AM
N.R.P.S. will stand for No Resistant Pest will Stand after Dr Carolina Cano-Prieto engineer them with her SynBio tools. Poster 38 #NP2025 #DTU_BRIGHT #sustainableagriculture
Saccharomyces Fans are scared of this black yeast! Check out how our PhD student Adrian Gadar-Lopez and his black yeast makes bioproducts like gangbusters. Poster #37 #NP2025 #DTU_BRIGHT #clickbait
January 7, 2025 at 3:56 AM
Saccharomyces Fans are scared of this black yeast! Check out how our PhD student Adrian Gadar-Lopez and his black yeast makes bioproducts like gangbusters. Poster #37 #NP2025 #DTU_BRIGHT #clickbait
Do you dream of making polyketides advanced materials with polyketide synthases? Check our PhD student Sidharth Jayachandran's poster at #NP2025 San Diego #OMG #DTU_BRIGHT
January 7, 2025 at 3:43 AM
Do you dream of making polyketides advanced materials with polyketide synthases? Check our PhD student Sidharth Jayachandran's poster at #NP2025 San Diego #OMG #DTU_BRIGHT
Reposted by We make molecules!
The #antiSMASH beta is now live on the website. There’s some minor updates and maybe a bug fix out two separating us from what will be in the final release. Please let up know if you run into any bugs.
Thanks to all the contributors for getting us past 100 detection rules and all the other updates
Thanks to all the contributors for getting us past 100 detection rules and all the other updates
December 17, 2024 at 9:47 PM
The #antiSMASH beta is now live on the website. There’s some minor updates and maybe a bug fix out two separating us from what will be in the final release. Please let up know if you run into any bugs.
Thanks to all the contributors for getting us past 100 detection rules and all the other updates
Thanks to all the contributors for getting us past 100 detection rules and all the other updates
Reposted by We make molecules!
StreptoCAD: An open-source software toolbox automating genome engineering workflows in streptomycetes https://www.biorxiv.org/content/10.1101/2024.12.19.629370v1
December 20, 2024 at 1:05 PM
StreptoCAD: An open-source software toolbox automating genome engineering workflows in streptomycetes https://www.biorxiv.org/content/10.1101/2024.12.19.629370v1
Reposted by We make molecules!
This time a little different story from our lab @dtu.dk: here we present #ActinoMation, a literate programming workflow to automate #Streptomyces conjugation on Opentron robots. www.biorxiv.org/content/10.1...
ActinoMation: a literate programming approach for medium-throughput robotic conjugation of Streptomyces spp.
The genus Streptomyces are valuable producers of antibiotics and other pharmaceutically important bioactive compounds. Advances in molecular engineering tools, such as CRISPR, has provided some access...
www.biorxiv.org
December 10, 2024 at 8:58 PM
This time a little different story from our lab @dtu.dk: here we present #ActinoMation, a literate programming workflow to automate #Streptomyces conjugation on Opentron robots. www.biorxiv.org/content/10.1...
Check out this fantastic work on how Drosophila comensal bacteria evolved host-specific adhesins to hang to their gut. by Dr. Karina GUTierrez. Of Carnegie @karinagtzga by the power of functional genomics and live imaging! www.science.org/doi/10.1126/... #f
A conserved bacterial genetic basis for commensal-host specificity
Animals selectively acquire specific symbiotic gut bacteria from their environments that aid host fitness. To colonize, a symbiont must locate its niche and sustain growth within the gut. Adhesins are...
www.science.org
December 5, 2024 at 10:10 PM
Check out this fantastic work on how Drosophila comensal bacteria evolved host-specific adhesins to hang to their gut. by Dr. Karina GUTierrez. Of Carnegie @karinagtzga by the power of functional genomics and live imaging! www.science.org/doi/10.1126/... #f
Today was a great day at YNP, DTU biosustain. we hosted a seminar by Dr. Manu Villalobos our winter guest. He showed us his systems biology tools for filamentous fungi and speed the Trichoderma gospel! #fungi #biocontrol #sustainabity
November 28, 2024 at 9:02 PM
Today was a great day at YNP, DTU biosustain. we hosted a seminar by Dr. Manu Villalobos our winter guest. He showed us his systems biology tools for filamentous fungi and speed the Trichoderma gospel! #fungi #biocontrol #sustainabity