Wael Kamel
@waelskamel.bsky.social
All about RNA regulation during virus infection @castello-lab.bsky.social @cvrinfo.bsky.social 🏴
Before @UniofOxford🇬🇧 @UU_University 🇸🇪 @CairoUniv 🇪🇬
Before @UniofOxford🇬🇧 @UU_University 🇸🇪 @CairoUniv 🇪🇬
Pinned
Wael Kamel
@waelskamel.bsky.social
· Dec 6
Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
Kamel et al. apply complementary approaches to elucidate the composition of Sindbis virus ribonucleoproteins. They identified a subset of nuclear proteins that selectively translocate to the cytoplasm, interact with viral RNA, and suppress virus infection. Among them, U2 snRNP emerges as a ribonucleoprotein complex with moonlighting antiviral activity.
www.cell.com
Super happy to have this as my first post"It is finally OUT!! After a pandemic, lab moving across the country!, 1+year under review and >120 panels later. 🧵"
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Reposted by Wael Kamel
New in Nature Comms: We applied metagenomic + targeted NGS to serum from febrile patients in Uganda. Post-COVID, LMICs have sequencing infrastructure that could be repurposed for pathogen discovery.
🔗 www.nature.com/articles/s41...
🔗 www.nature.com/articles/s41...
Uncovering the viral aetiology of undiagnosed acute febrile illness in Uganda using metagenomic sequencing - Nature Communications
Acute febrile illness is common in sub-Saharan Africa and causative agents are often unknown. Here, the authors perform metagenomic sequencing on samples from patients with acute febrile illness in Ug...
www.nature.com
March 27, 2025 at 12:04 AM
New in Nature Comms: We applied metagenomic + targeted NGS to serum from febrile patients in Uganda. Post-COVID, LMICs have sequencing infrastructure that could be repurposed for pathogen discovery.
🔗 www.nature.com/articles/s41...
🔗 www.nature.com/articles/s41...
Reposted by Wael Kamel
🎉 We are very excited to have our recent @naturecomms.bsky.social publication chosen to be featured on a Editors’ Highlights webpage specific to public health.
www.nature.com/collections/...
@emcat1.bsky.social & Shirin Ashraf
www.nature.com/collections/...
@emcat1.bsky.social & Shirin Ashraf
Public health
Our recent highlights in the field of public health, including epidemiological studies investigating the social, environmental, genetic, and behavioural ...
www.nature.com
April 3, 2025 at 10:48 AM
🎉 We are very excited to have our recent @naturecomms.bsky.social publication chosen to be featured on a Editors’ Highlights webpage specific to public health.
www.nature.com/collections/...
@emcat1.bsky.social & Shirin Ashraf
www.nature.com/collections/...
@emcat1.bsky.social & Shirin Ashraf
Reposted by Wael Kamel
What's going on with bird flu in the UK at the moment? I wrote a piece for @uk.theconversation.com explaining what we know at the moment, and why it's not yet time to worry
theconversation.com/bird-flu-cas...
theconversation.com/bird-flu-cas...
Bird flu cases surging in UK but risk to humans remains low
Restrictions have recently been put in place in England and Scotland to curb the spread of bird flu.
theconversation.com
January 30, 2025 at 5:22 PM
What's going on with bird flu in the UK at the moment? I wrote a piece for @uk.theconversation.com explaining what we know at the moment, and why it's not yet time to worry
theconversation.com/bird-flu-cas...
theconversation.com/bird-flu-cas...
Reposted by Wael Kamel
🦸 Hidden superheroes in our cells!?
@waelskamel.bsky.social, @castello-lab.bsky.social & the Rosalind Franklin Institute have uncovered how a team of cellular “superheroes” leap into action to stop viruses in their tracks.
More: gla.ac.uk/research/az/...
The study: cell.com/molecular-ce...
@waelskamel.bsky.social, @castello-lab.bsky.social & the Rosalind Franklin Institute have uncovered how a team of cellular “superheroes” leap into action to stop viruses in their tracks.
More: gla.ac.uk/research/az/...
The study: cell.com/molecular-ce...
December 12, 2024 at 4:28 PM
🦸 Hidden superheroes in our cells!?
@waelskamel.bsky.social, @castello-lab.bsky.social & the Rosalind Franklin Institute have uncovered how a team of cellular “superheroes” leap into action to stop viruses in their tracks.
More: gla.ac.uk/research/az/...
The study: cell.com/molecular-ce...
@waelskamel.bsky.social, @castello-lab.bsky.social & the Rosalind Franklin Institute have uncovered how a team of cellular “superheroes” leap into action to stop viruses in their tracks.
More: gla.ac.uk/research/az/...
The study: cell.com/molecular-ce...
Cake time!!! We literally ate our model!! and ...it is delicious😋
December 11, 2024 at 10:31 AM
Cake time!!! We literally ate our model!! and ...it is delicious😋
Reposted by Wael Kamel
Nuclear RBPs moonlighting in the cytoplasm as part of the host response to Sindbis virus. Another beautiful work by Alfredo Castelo’s group. I’m struggling to keep up with reading all the amazing papers they’ve published in the last few months.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
Kamel et al. apply complementary approaches to elucidate the composition of Sindbis virus ribonucleoproteins. They identified a subset of nuclear proteins that selectively translocate to the cytoplasm, interact with viral RNA, and suppress virus infection. Among them, U2 snRNP emerges as a ribonucleoprotein complex with moonlighting antiviral activity.
www.cell.com
December 6, 2024 at 3:24 PM
Nuclear RBPs moonlighting in the cytoplasm as part of the host response to Sindbis virus. Another beautiful work by Alfredo Castelo’s group. I’m struggling to keep up with reading all the amazing papers they’ve published in the last few months.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Reposted by Wael Kamel
I am delighted that our long standing close collaboration with AlfredoCastello lab has led to yet another very exciting publication in Mol Cell: thanks so much to Wael and Alfredo for taking the lead.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
Kamel et al. apply complementary approaches to elucidate the composition of Sindbis virus ribonucleoproteins. They identified a subset of nuclear proteins that selectively translocate to the cytoplasm, interact with viral RNA, and suppress virus infection. Among them, U2 snRNP emerges as a ribonucleoprotein complex with moonlighting antiviral activity.
www.cell.com
December 7, 2024 at 1:08 PM
I am delighted that our long standing close collaboration with AlfredoCastello lab has led to yet another very exciting publication in Mol Cell: thanks so much to Wael and Alfredo for taking the lead.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Super happy to have this as my first post"It is finally OUT!! After a pandemic, lab moving across the country!, 1+year under review and >120 panels later. 🧵"
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
Kamel et al. apply complementary approaches to elucidate the composition of Sindbis virus ribonucleoproteins. They identified a subset of nuclear proteins that selectively translocate to the cytoplasm, interact with viral RNA, and suppress virus infection. Among them, U2 snRNP emerges as a ribonucleoprotein complex with moonlighting antiviral activity.
www.cell.com
December 6, 2024 at 10:42 AM
Super happy to have this as my first post"It is finally OUT!! After a pandemic, lab moving across the country!, 1+year under review and >120 panels later. 🧵"
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...