Vincent Paget-Blanc, Ph.D.
@vincentpb.bsky.social
Neuroscientist at CNRS univbordeaux prev IITalk UniGenova. I tweet about science and research in English/French. Sometimes random pictures
I am thrilled to finally present my first Ph.D. research paper, where we delved into the molecular mechanisms behind the decline in behavioral flexibility following extensive training on an appetitive task. If you are interested in the topic keep an eye out for more insights from my Ph.D. research!
Instrumental actions rely on flexible, goal-directed #behavior, but can become more rigid & habit-like with repetition. @vincentpb.bsky.social &co show that decreased adaptive signaling capacity of #striatal mGluR1/5 is key to this loss of #BehavioralFlexibility @plosbiology.org 🧪 plos.io/3JaRLAk
August 4, 2025 at 8:41 PM
I am thrilled to finally present my first Ph.D. research paper, where we delved into the molecular mechanisms behind the decline in behavioral flexibility following extensive training on an appetitive task. If you are interested in the topic keep an eye out for more insights from my Ph.D. research!
Happy to finally share our detailed protocol on how to purify afference-specific synaptosome populations using fluorescence-activated synaptosome sorting! I hope it will help anyone who wants to try to perform FASS link.springer.com/protocol/10....
Purification of Afference-Specific Synaptosome Populations Using Fluorescence-Activated Synaptosome Sorting
The central nervous system contains a complex intermingled network of neuronal, glial, and vascular cells, and for several decades, neurobiologists have used subcellular fractionation methods to analy...
link.springer.com
April 13, 2025 at 8:54 AM
Happy to finally share our detailed protocol on how to purify afference-specific synaptosome populations using fluorescence-activated synaptosome sorting! I hope it will help anyone who wants to try to perform FASS link.springer.com/protocol/10....
Reposted by Vincent Paget-Blanc, Ph.D.
New preprint from the MemTraS team ! www.biorxiv.org/content/10.1...
Great collaboration with @fronzeslab.bsky.social and Vladan Lucic to determine the first cryo electron tomography images of dopamine "synapses" extracted from adult mouse brain.
Great collaboration with @fronzeslab.bsky.social and Vladan Lucic to determine the first cryo electron tomography images of dopamine "synapses" extracted from adult mouse brain.
February 10, 2025 at 4:39 PM
New preprint from the MemTraS team ! www.biorxiv.org/content/10.1...
Great collaboration with @fronzeslab.bsky.social and Vladan Lucic to determine the first cryo electron tomography images of dopamine "synapses" extracted from adult mouse brain.
Great collaboration with @fronzeslab.bsky.social and Vladan Lucic to determine the first cryo electron tomography images of dopamine "synapses" extracted from adult mouse brain.