Our latest study is now out in @narjournal.bsky.social‬: we identify a post-transcriptional bottleneck in interferon gamma signaling that hinges on proper maturation of JAK2 mRNA.
Paper: academic.oup.com/nar/article/...

New paper out in @natcomms.nature.com! A surprising story of a "non-conserved" protein that's vital for human cell fitness! Fantastic work by Alexandra Shulkina in collaboration with the @lcochella.bsky.social & @clausenlab.bsky.social labs.