Valerie Verhasselt
verhasselt.bsky.social
Valerie Verhasselt
@verhasselt.bsky.social
Director of LRF Centre for Immunology and Breastfeeding, Professor, Neonatal Immunologist, Creative thinker, Admirer of Nature
What if one natural and free intervention at birth could help prevent food allergies? Infants who had compromised #colostrum intake, due to formula supplements, had 5x higher risk of #peanutallergy and 11x higher risk of multiple #foodallergies.
onlinelibrary.wiley.com/doi/full/10....
September 19, 2025 at 8:55 AM
Reposted by Valerie Verhasselt
Hello Mucosal Immunologists in the Asia/Pacific (and beyond) - only 2 weeks left to submit your abstract👇. Who wouldn’t want to escape to sunny Noosa in May? An excellent lineup @hepworth-lab.bsky.social @verhasselt.bsky.social @hay-mish.bsky.social and more!
*Attention all mucosal immunologists/microbiologists* A reminder to register and submit your abstract (closing Jan 31st) to MIMS 2025 in sunny Noosa! A stellar lineup of national and international speakers👇👇👇 For more information and register at www.immunology.org.au/events/ASI-M...

See you there!
January 14, 2025 at 7:15 AM
Topical #skin #vaccine without the need of a needle by engineering skin commensal Staph epidermidis!

www.nature.com/articles/s41...
Discovery and engineering of the antibody response to a prominent skin commensal - Nature
Nature - Discovery and engineering of the antibody response to a prominent skin commensal
www.nature.com
December 22, 2024 at 3:56 PM
A must read !!! Skin autonomous immune response to the microbiota by @yasmineBelkaid and team !

www.nature.com/articles/s41....
Skin autonomous antibody production regulates host-microbiota interactions - Nature
Nature - Skin autonomous antibody production regulates host-microbiota interactions
www.nature.com
December 22, 2024 at 3:44 PM
#Pregnancy and #lactation - a unique time of tissue development in adult life! This paper shows how the maternal #gutepithelium expands during pregnancy and lactation, and how this is necessary for the healthy development of the offspring after birth.
www.nature.com/articles/s41...
RANK drives structured intestinal epithelial expansion during pregnancy - Nature
The RANK–RANKL pathway drives intestinal epithelial expansion in pregnancy and lactation.
www.nature.com
December 17, 2024 at 12:13 PM
Reposted by Valerie Verhasselt
Maternal gut microbiota influence stem cell function in offspring

”the maternal microbiome and offspring’s stem cells are bona fide candidates that seem to play central roles governing early life development”

www.cell.com/cell-stem-ce...
Maternal gut microbiota influence stem cell function in offspring
Dang et al. demonstrate that maternal gut microbiota during pregnancy program the intestinal and neuronal stem cell characteristics of offspring. This crosstalk between maternal microbiota and fetal stem cells, mediated by circulating metabolites, impacts offspring development, long-term health, behavior, and disease recovery.
www.cell.com
December 11, 2024 at 10:42 PM
#Oraltolerance
Great review mainly focusing on adults where maintening oral tolerance is important for health www.nature.com/articles/s41...
What about #earlylife, when the induction of oral tolerance is key to #development?
A newborn's perspective on immune response to food
doi.org/10.1111/imr....
The renaissance of oral tolerance: merging tradition and new insights - Nature Reviews Immunology
Oral tolerance describes how the oral administration of harmless antigens (such as dietary proteins) leads to systemic immune unresponsiveness to these antigens. Its failure can lead to conditions suc...
www.nature.com
November 28, 2024 at 2:02 AM