Francisca Vazquez PhD
@vazquezf.bsky.social
Cofounder and Director | Cancer Dependency Map Consortium #depmap | Cancer Target Discovery @Broad Institute
https://target-discovery.depmap.org/
https://target-discovery.depmap.org/
Reposted by Francisca Vazquez PhD
🧬 Excited to announce the 2nd Euro Cancer DepMap Symposium bringing together leading minds in functional genomics, cancer vulnerabilities, AI, CRISPR and anti-cancer target discovery.📍Join us in Milan for cutting-edge science, open discussion & collaboration. #EuroDepMap #CancerResearch #CRISPR
June 11, 2025 at 3:00 PM
🧬 Excited to announce the 2nd Euro Cancer DepMap Symposium bringing together leading minds in functional genomics, cancer vulnerabilities, AI, CRISPR and anti-cancer target discovery.📍Join us in Milan for cutting-edge science, open discussion & collaboration. #EuroDepMap #CancerResearch #CRISPR
Reposted by Francisca Vazquez PhD
For those of you interested in cancer synthetic lethality, this should be a v interesting Gordon Conference organised by @mgarnett.bsky.social @vazquezf.bsky.social & Benjamin Schwartz- highly recommended ! www.grc.org/synthetic-le...
2025 Synthetic Lethality Approaches in Oncology Conference GRC
The 2025 Gordon Research Conference on Synthetic Lethality Approaches in Oncology will be held in Portland, Maine. Apply today to reserve your spot.
www.grc.org
March 20, 2025 at 1:32 PM
For those of you interested in cancer synthetic lethality, this should be a v interesting Gordon Conference organised by @mgarnett.bsky.social @vazquezf.bsky.social & Benjamin Schwartz- highly recommended ! www.grc.org/synthetic-le...
Reposted by Francisca Vazquez PhD
New Gordon Research Conference Alert: Synthetic Lethality Approaches in Oncology. www.grc.org/synthetic-le....
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
February 25, 2025 at 4:17 PM
New Gordon Research Conference Alert: Synthetic Lethality Approaches in Oncology. www.grc.org/synthetic-le....
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
Reposted by Francisca Vazquez PhD
UCD @ucddublin.bsky.social are recruiting fifty early-career faculty through the Ad Astra Fellowship programme. In the School of Medicine there are two positions related to AI in Medicine that might be of particular interest. Deadline 21st February. Full details here: www.ucd.ie/adastrafello...
UCD Ad Astra Fellows
www.ucd.ie
February 10, 2025 at 11:59 AM
UCD @ucddublin.bsky.social are recruiting fifty early-career faculty through the Ad Astra Fellowship programme. In the School of Medicine there are two positions related to AI in Medicine that might be of particular interest. Deadline 21st February. Full details here: www.ucd.ie/adastrafello...
Reposted by Francisca Vazquez PhD
Exciting new synthetic lethal target emerging from #depmap data 🧪🧬
Frequent passenger mutations in genes involved in mRNA quality control lead to a dependency on PELO-HBS1L
Congratulations to the DepMap team! @vazquezf.bsky.social
#depmap #cancertarget #syntheticlethal
Frequent passenger mutations in genes involved in mRNA quality control lead to a dependency on PELO-HBS1L
Congratulations to the DepMap team! @vazquezf.bsky.social
#depmap #cancertarget #syntheticlethal
SKI complex loss renders 9p21.3-deleted or MSI-H cancers dependent on PELO - Nature
Analysis of large-scale CRISPR screening data, combined with experiments in patient-derived tumour organoid models, identifies PELO as a potential therapeutic target in chromosomal 9p21.3-deleted canc...
www.nature.com
February 5, 2025 at 10:01 PM
Exciting new synthetic lethal target emerging from #depmap data 🧪🧬
Frequent passenger mutations in genes involved in mRNA quality control lead to a dependency on PELO-HBS1L
Congratulations to the DepMap team! @vazquezf.bsky.social
#depmap #cancertarget #syntheticlethal
Frequent passenger mutations in genes involved in mRNA quality control lead to a dependency on PELO-HBS1L
Congratulations to the DepMap team! @vazquezf.bsky.social
#depmap #cancertarget #syntheticlethal
(1/3) Excited to share our latest work using
@depmap.org to uncover a new synthetic lethality in two distinct patient populations!
We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO
#CancerResearch #SyntheticLethality #Genomics #DepMap
@depmap.org to uncover a new synthetic lethality in two distinct patient populations!
We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO
#CancerResearch #SyntheticLethality #Genomics #DepMap
SKI complex loss renders 9p21.3-deleted or MSI-H cancers dependent on PELO - Nature
Analysis of large-scale CRISPR screening data, combined with experiments in patient-derived tumour organoid models, identifies PELO as a potential therapeutic target in chromosomal 9p21.3-deleted canc...
nature.com
February 6, 2025 at 1:07 PM
(1/3) Excited to share our latest work using
@depmap.org to uncover a new synthetic lethality in two distinct patient populations!
We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO
#CancerResearch #SyntheticLethality #Genomics #DepMap
@depmap.org to uncover a new synthetic lethality in two distinct patient populations!
We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO
#CancerResearch #SyntheticLethality #Genomics #DepMap
Reposted by Francisca Vazquez PhD
It's time to tackle rare cancers together - both a scientific opportunity and a moral imperative! I've shared a few brief thoughts in the Trends in Cancer opinions perspective on this topic - out now online www.cell.com/trends/cance...
Think zebras: challenges and opportunities for treating rare cancers
The adage goes, ‘When you hear hoofbeats, think of horses, not zebras’. However, placing
less emphasis on ‘zebras’ – both in the clinical and research space – can prevent
many rare cancers from being ...
www.cell.com
January 29, 2025 at 10:22 PM
It's time to tackle rare cancers together - both a scientific opportunity and a moral imperative! I've shared a few brief thoughts in the Trends in Cancer opinions perspective on this topic - out now online www.cell.com/trends/cance...
Reposted by Francisca Vazquez PhD
📣Registration is now open for an exciting Gordon Conference on synthetic lethality organized by Ben Schwartz (GSK), Mathew Garnett (Sanger), and Francisca Vazquez (DepMap Director, Broad Institute)
Highly recommended!
Register here
grc.org/synthetic-le...
Highly recommended!
Register here
grc.org/synthetic-le...
2025 Synthetic Lethality Approaches in Oncology Conference GRC
The 2025 Gordon Research Conference on Synthetic Lethality Approaches in Oncology will be held in Portland, Maine. Apply today to reserve your spot.
grc.org
January 29, 2025 at 8:05 PM
📣Registration is now open for an exciting Gordon Conference on synthetic lethality organized by Ben Schwartz (GSK), Mathew Garnett (Sanger), and Francisca Vazquez (DepMap Director, Broad Institute)
Highly recommended!
Register here
grc.org/synthetic-le...
Highly recommended!
Register here
grc.org/synthetic-le...
Reposted by Francisca Vazquez PhD
We will be hosting the International Conference on Systems Biology (ICSB) in Dublin this year – 5-9th October icsb2025.com/registration/ #ICSB2025
January 29, 2025 at 4:50 PM
We will be hosting the International Conference on Systems Biology (ICSB) in Dublin this year – 5-9th October icsb2025.com/registration/ #ICSB2025
Reposted by Francisca Vazquez PhD
DepMap keeps growing—and so does the portal!
To help navigate the portal, new in 24Q4 we’ve launched a new resource page 🚀! Check it out and share your feedback.
To help navigate the portal, new in 24Q4 we’ve launched a new resource page 🚀! Check it out and share your feedback.
Depmap Resources | Depmap Portal
depmap.org
December 20, 2024 at 8:03 AM
DepMap keeps growing—and so does the portal!
To help navigate the portal, new in 24Q4 we’ve launched a new resource page 🚀! Check it out and share your feedback.
To help navigate the portal, new in 24Q4 we’ve launched a new resource page 🚀! Check it out and share your feedback.
Reposted by Francisca Vazquez PhD
We’re kicking off the first DepMap post with a bang!
⭐ 35 CRISPR screens
⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org)
⭐ First 281 WES -> WGS
⭐ New Resources page
📣 DepMap is now on dbGaP (phs003444.v1.p1)
Read our release notes for more info!
⭐ 35 CRISPR screens
⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org)
⭐ First 281 WES -> WGS
⭐ New Resources page
📣 DepMap is now on dbGaP (phs003444.v1.p1)
Read our release notes for more info!
December 18, 2024 at 7:07 PM
We’re kicking off the first DepMap post with a bang!
⭐ 35 CRISPR screens
⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org)
⭐ First 281 WES -> WGS
⭐ New Resources page
📣 DepMap is now on dbGaP (phs003444.v1.p1)
Read our release notes for more info!
⭐ 35 CRISPR screens
⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org)
⭐ First 281 WES -> WGS
⭐ New Resources page
📣 DepMap is now on dbGaP (phs003444.v1.p1)
Read our release notes for more info!