Tobias Raisch
@traisch.bsky.social
Biochemist and Structural Biologist | Project group leader MPI Dortmund | He/him | Vegan bike punk #LeaveNoOneBehind
Reposted by Tobias Raisch
Nature research paper: Myeloperoxidase transforms chromatin into neutrophil extracellular traps
go.nature.com/4pxKgV6
go.nature.com/4pxKgV6
Myeloperoxidase transforms chromatin into neutrophil extracellular traps - Nature
Myeloperoxidase, a highly expressed neutrophil protein, disassembles nucleosomes, facilitating neutrophil extracellular trap (NET) formation, and binds stably to NETs extracellularly.
go.nature.com
September 20, 2025 at 11:37 AM
Nature research paper: Myeloperoxidase transforms chromatin into neutrophil extracellular traps
go.nature.com/4pxKgV6
go.nature.com/4pxKgV6
Reposted by Tobias Raisch
📃 New paper alert!
The Zychlinsky Lab and @raunser-lab.bsky.social identified the first protein that converts chromatin into an immune effector: Myeloperoxidase transforms chromatin into neutrophil extracellular traps. Now published in @nature.com:
www.nature.com/articles/s41...
The Zychlinsky Lab and @raunser-lab.bsky.social identified the first protein that converts chromatin into an immune effector: Myeloperoxidase transforms chromatin into neutrophil extracellular traps. Now published in @nature.com:
www.nature.com/articles/s41...
Myeloperoxidase transforms chromatin into neutrophil extracellular traps - Nature
Myeloperoxidase, a highly expressed neutrophil protein, disassembles nucleosomes, facilitating neutrophil extracellular trap (NET) formation, and binds stably to NETs extracellularly.
www.nature.com
September 19, 2025 at 7:16 AM
📃 New paper alert!
The Zychlinsky Lab and @raunser-lab.bsky.social identified the first protein that converts chromatin into an immune effector: Myeloperoxidase transforms chromatin into neutrophil extracellular traps. Now published in @nature.com:
www.nature.com/articles/s41...
The Zychlinsky Lab and @raunser-lab.bsky.social identified the first protein that converts chromatin into an immune effector: Myeloperoxidase transforms chromatin into neutrophil extracellular traps. Now published in @nature.com:
www.nature.com/articles/s41...
We just published this paper of which I am immensely proud: www.nature.com/articles/s41...
In the study, we uncover how the enzyme MPO disassembles #nucleosomes in a process called NETosis, a funky mechanism of #neutrophils to kill #pathogens that you might have never heard of.
Let's dive in... 🧵
In the study, we uncover how the enzyme MPO disassembles #nucleosomes in a process called NETosis, a funky mechanism of #neutrophils to kill #pathogens that you might have never heard of.
Let's dive in... 🧵
Myeloperoxidase transforms chromatin into neutrophil extracellular traps - Nature
Myeloperoxidase, a highly expressed neutrophil protein, disassembles nucleosomes, facilitating neutrophil extracellular trap (NET) formation, and binds stably to NETs extracellularly.
www.nature.com
September 18, 2025 at 3:39 PM
We just published this paper of which I am immensely proud: www.nature.com/articles/s41...
In the study, we uncover how the enzyme MPO disassembles #nucleosomes in a process called NETosis, a funky mechanism of #neutrophils to kill #pathogens that you might have never heard of.
Let's dive in... 🧵
In the study, we uncover how the enzyme MPO disassembles #nucleosomes in a process called NETosis, a funky mechanism of #neutrophils to kill #pathogens that you might have never heard of.
Let's dive in... 🧵
I have an open postdoc position in my group at @mpi-dortmund.bsky.social @maxplanck.de!
If you are passionate about structural biology and/or membrane proteins, apply today!
The position is initially funded for two years, starting from this October. Deadline for application is on July 15th.
If you are passionate about structural biology and/or membrane proteins, apply today!
The position is initially funded for two years, starting from this October. Deadline for application is on July 15th.
July 1, 2025 at 7:47 PM
I have an open postdoc position in my group at @mpi-dortmund.bsky.social @maxplanck.de!
If you are passionate about structural biology and/or membrane proteins, apply today!
The position is initially funded for two years, starting from this October. Deadline for application is on July 15th.
If you are passionate about structural biology and/or membrane proteins, apply today!
The position is initially funded for two years, starting from this October. Deadline for application is on July 15th.
1/3 Today I can proudly present the first preprint from my project group!
biorxiv.org/content/10.1...
We determined the CryoEM structure of the Slo1 potassium channel in complex with the regulatory subunit γ1 and propose a mechanism of how γ1 can activate Slo1.
biorxiv.org/content/10.1...
We determined the CryoEM structure of the Slo1 potassium channel in complex with the regulatory subunit γ1 and propose a mechanism of how γ1 can activate Slo1.
November 4, 2023 at 10:56 AM
1/3 Today I can proudly present the first preprint from my project group!
biorxiv.org/content/10.1...
We determined the CryoEM structure of the Slo1 potassium channel in complex with the regulatory subunit γ1 and propose a mechanism of how γ1 can activate Slo1.
biorxiv.org/content/10.1...
We determined the CryoEM structure of the Slo1 potassium channel in complex with the regulatory subunit γ1 and propose a mechanism of how γ1 can activate Slo1.
Together with Stefan Raunser, I wrote a little review on neurotoxic insecticides acting on ion channels.
We focus on structures and mechanisms and try to reveal similarities in modes of action between chemically diverse compounds. In the end, many act surprisingly similar!
rdcu.be/doHyK
We focus on structures and mechanisms and try to reveal similarities in modes of action between chemically diverse compounds. In the end, many act surprisingly similar!
rdcu.be/doHyK
October 16, 2023 at 4:43 PM
Together with Stefan Raunser, I wrote a little review on neurotoxic insecticides acting on ion channels.
We focus on structures and mechanisms and try to reveal similarities in modes of action between chemically diverse compounds. In the end, many act surprisingly similar!
rdcu.be/doHyK
We focus on structures and mechanisms and try to reveal similarities in modes of action between chemically diverse compounds. In the end, many act surprisingly similar!
rdcu.be/doHyK