Toth-Petroczy lab
@tothpetroczylab.bsky.social
Protein evolution, IDRs, bimolecular condensates, phenotypic mutations. Science and fun from the ATPlab.
Reposted by Toth-Petroczy lab
Schering Young Investigator Award 2025 by the Schering Stiftung for Agnes Toth-Petroczy @tothpetroczylab.bsky.social @mpi-cbg.de @csbdresden.bsky.social. She receives the award for her work on the evolution, diversity, and function of proteins. Congratulations! 🎉 www.mpi-cbg.de/news-outreac...
New Perspectives on the Hidden World of Proteins
Schering Young Investigator Award 2025 goes to Agnes Toth-Petroczy
www.mpi-cbg.de
September 30, 2025 at 7:49 AM
Schering Young Investigator Award 2025 by the Schering Stiftung for Agnes Toth-Petroczy @tothpetroczylab.bsky.social @mpi-cbg.de @csbdresden.bsky.social. She receives the award for her work on the evolution, diversity, and function of proteins. Congratulations! 🎉 www.mpi-cbg.de/news-outreac...
Reposted by Toth-Petroczy lab
AI can now generate fake microscopy images that are nearly impossible to detect. A serious threat to scientific integrity—and we’re not prepared for it.
Commentary in @natnano.nature.com
#nanotechnology
Commentary in @natnano.nature.com
#nanotechnology
September 15, 2025 at 10:39 AM
AI can now generate fake microscopy images that are nearly impossible to detect. A serious threat to scientific integrity—and we’re not prepared for it.
Commentary in @natnano.nature.com
#nanotechnology
Commentary in @natnano.nature.com
#nanotechnology
Reposted by Toth-Petroczy lab
🧬 We're excited to host the 13th Symposium on Structural #Proteomics at HT in Milan on 6–8 Oct 25! Join this international meeting with talks on protein structure and interactions by crosslinking MS, HDX-MS, native MS, chemoproteomics & more 👉 ssp2025.squarespace.com
▶️ @ssp2025.bsky.social
▶️ @ssp2025.bsky.social
July 24, 2025 at 12:32 PM
🧬 We're excited to host the 13th Symposium on Structural #Proteomics at HT in Milan on 6–8 Oct 25! Join this international meeting with talks on protein structure and interactions by crosslinking MS, HDX-MS, native MS, chemoproteomics & more 👉 ssp2025.squarespace.com
▶️ @ssp2025.bsky.social
▶️ @ssp2025.bsky.social
Reposted by Toth-Petroczy lab
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Novel Research in Biological Artificial Intelligence
Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.
www.mpi-cbg.de
June 26, 2025 at 11:26 AM
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Reposted by Toth-Petroczy lab
Scientific research is at the heart of Israel’s success and has worldwide benefits. Our work will continue despite adversity, says Alon Chen
https://go.nature.com/40wXMx6
https://go.nature.com/40wXMx6
How we’re rebuilding the Weizmann Institute — and our hopes for a better future
Scientific research is at the heart of Israel’s success and has worldwide benefits. Our work will continue despite adversity.
go.nature.com
July 3, 2025 at 1:30 PM
Scientific research is at the heart of Israel’s success and has worldwide benefits. Our work will continue despite adversity, says Alon Chen
https://go.nature.com/40wXMx6
https://go.nature.com/40wXMx6
Reposted by Toth-Petroczy lab
Big news 🎉 We are excited to announce the new TUD graduate school "Biomolecular Condensates: From Physics to Biological Functions", with 12 members from PoL! Through this school, we will train a new generation of scientists working on #condensates at the interphase between theory and experiments 🤓⤵️
Hochaktuelles Themenfeld an der Schnittstelle von Physik, Biologie und Polymerforschung: Die @dfg.de fördert ab 2026 mit rund 7 Millionen Euro ein neues Graduiertenkolleg zur Erforschung biomolekularer Kondensate in #Dresden. 🔬
ℹ️ tu-dresden.de/tu-dresden/n...
ℹ️ tu-dresden.de/tu-dresden/n...
June 18, 2025 at 10:59 AM
Big news 🎉 We are excited to announce the new TUD graduate school "Biomolecular Condensates: From Physics to Biological Functions", with 12 members from PoL! Through this school, we will train a new generation of scientists working on #condensates at the interphase between theory and experiments 🤓⤵️
Reposted by Toth-Petroczy lab
The latest release was supported by the #condesathon joined by @mpi-cbg.de condensate community🤩
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
June 11, 2025 at 1:33 PM
The latest release was supported by the #condesathon joined by @mpi-cbg.de condensate community🤩
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
Reposted by Toth-Petroczy lab
Related science sketch video by @marionamec.bsky.social www.youtube.com/watch?v=0REv...
Condensates Inside Condensates—Triggering Disease?
YouTube video by MPI-CBG
www.youtube.com
May 28, 2025 at 3:09 PM
Related science sketch video by @marionamec.bsky.social www.youtube.com/watch?v=0REv...
Are you looking for homologous sequences but alignments do not seem to work? SHARK is available as a webserver: compare sequences or search against precomputed IDR datasets: bio-shark.org @narjournal.bsky.social @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
SHARK: web server for alignment-free homology assessment for intrinsically disordered and unalignable protein regions
Abstract. Whereas alignment has been fundamental to sequence-based assessments of protein homology, it is ineffective for intrinsically disordered regions
doi.org
May 28, 2025 at 9:24 PM
Are you looking for homologous sequences but alignments do not seem to work? SHARK is available as a webserver: compare sequences or search against precomputed IDR datasets: bio-shark.org @narjournal.bsky.social @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
Reposted by Toth-Petroczy lab
One week left to apply to the Physics of Life MSc this year! Students learn first-class research skills and can also avail of #scholarships to aid their studies.
Learn more and apply: physics-of-life.tu-dresden.de/career-educa...
#internationalstudents #MSc #EnglishMSc #Physics #studyabroad
Learn more and apply: physics-of-life.tu-dresden.de/career-educa...
#internationalstudents #MSc #EnglishMSc #Physics #studyabroad
Good news: there will be 3 scholarships available for Physics of Life MSc students starting in 2025!
✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.
Apply now ➡️ tud.link/vejrmx
#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology
✅ €300/month for 1 year
✅ No separate application—admitted students are automatically considered.
Apply now ➡️ tud.link/vejrmx
#Biophysics #PhysicsofLife #StudyinGermany #Masters #Biology
May 21, 2025 at 9:39 AM
One week left to apply to the Physics of Life MSc this year! Students learn first-class research skills and can also avail of #scholarships to aid their studies.
Learn more and apply: physics-of-life.tu-dresden.de/career-educa...
#internationalstudents #MSc #EnglishMSc #Physics #studyabroad
Learn more and apply: physics-of-life.tu-dresden.de/career-educa...
#internationalstudents #MSc #EnglishMSc #Physics #studyabroad
Reposted by Toth-Petroczy lab
Exciting that CD-CODE is now connected to THE go-to resource for everything protein-related!
It's a great step forward, directing further developments and outlook for our project @tothpetroczylab.bsky.social @mscheremetjew.bsky.social 🥳
It's a great step forward, directing further developments and outlook for our project @tothpetroczylab.bsky.social @mscheremetjew.bsky.social 🥳
We're really excited that CD-CODE is now cross-referenced by #UniProt and has already been included in the latest release: www.uniprot.org/release-note...
Spreading knowledge about #biomolecular #condensates 🥳
@ebi.embl.org @sib.swiss @mpi-cbg.de @tothpetroczylab.bsky.social @hymanlab.bsky.social
Spreading knowledge about #biomolecular #condensates 🥳
@ebi.embl.org @sib.swiss @mpi-cbg.de @tothpetroczylab.bsky.social @hymanlab.bsky.social
UniProt
UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.
www.uniprot.org
April 28, 2025 at 1:59 PM
Exciting that CD-CODE is now connected to THE go-to resource for everything protein-related!
It's a great step forward, directing further developments and outlook for our project @tothpetroczylab.bsky.social @mscheremetjew.bsky.social 🥳
It's a great step forward, directing further developments and outlook for our project @tothpetroczylab.bsky.social @mscheremetjew.bsky.social 🥳
Deep learning tools predict variants in disordered regions with lower sensitivity. Just published by FedericaLuppino, @swlenz.bsky.social and WillisChow @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social bmcgenomics.biomedcentral.com/articles/10....
Deep learning tools predict variants in disordered regions with lower sensitivity - BMC Genomics
Background The recent AI breakthrough of AlphaFold2 has revolutionized 3D protein structural modeling, proving crucial for protein design and variant effects prediction. However, intrinsically disorde...
bmcgenomics.biomedcentral.com
April 16, 2025 at 9:43 PM
Deep learning tools predict variants in disordered regions with lower sensitivity. Just published by FedericaLuppino, @swlenz.bsky.social and WillisChow @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social bmcgenomics.biomedcentral.com/articles/10....
Reposted by Toth-Petroczy lab
New Publication of the @tothpetroczylab.bsky.social: The group found that prediction tools are less sensitive in intrinsically disordered regions of proteins (IDRs). Since they are common & important, new methods tailored to these regions are needed. bmcgenomics.biomedcentral.com/articles/10....
April 14, 2025 at 3:54 PM
New Publication of the @tothpetroczylab.bsky.social: The group found that prediction tools are less sensitive in intrinsically disordered regions of proteins (IDRs). Since they are common & important, new methods tailored to these regions are needed. bmcgenomics.biomedcentral.com/articles/10....
Reposted by Toth-Petroczy lab
The @tothpetroczylab.bsky.social together with the @albertilab-tud.bsky.social developed SHARK-capture to detect recurring patterns (motifs) in intrinsically disordered protein regions (IDRs). Publication in Protein Science. www.mpi-cbg.de/news-outreac...
March 25, 2025 at 3:45 PM
The @tothpetroczylab.bsky.social together with the @albertilab-tud.bsky.social developed SHARK-capture to detect recurring patterns (motifs) in intrinsically disordered protein regions (IDRs). Publication in Protein Science. www.mpi-cbg.de/news-outreac...
Reposted by Toth-Petroczy lab
You can download my protein structure-inspired artwork from pdb webpage:
pdb101.rcsb.org/sci-art/bezs...
@rcsbpdb.bsky.social
@pdbeurope.bsky.social
#sciart
pdb101.rcsb.org/sci-art/bezs...
@rcsbpdb.bsky.social
@pdbeurope.bsky.social
#sciart
PDB101: Irina Bezsonova Gallery
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb101.rcsb.org
March 15, 2025 at 11:42 AM
You can download my protein structure-inspired artwork from pdb webpage:
pdb101.rcsb.org/sci-art/bezs...
@rcsbpdb.bsky.social
@pdbeurope.bsky.social
#sciart
pdb101.rcsb.org/sci-art/bezs...
@rcsbpdb.bsky.social
@pdbeurope.bsky.social
#sciart
Identifying functional motifs in disordered regions is challenging. We gave it a try. Check out SHARK-capture, an alignment-free method to detect SLiMs. Congrats Chi Fung Willis Chow @swlenz.bsky.social et al. @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social doi.org/10.1002/pro....
SHARK‐capture identifies functional motifs in intrinsically disordered protein regions
Increasing insights into how sequence motifs in intrinsically disordered regions (IDRs) provide functions underscore the need for systematic motif detection. Contrary to structured regions where moti...
doi.org
March 18, 2025 at 8:06 PM
Identifying functional motifs in disordered regions is challenging. We gave it a try. Check out SHARK-capture, an alignment-free method to detect SLiMs. Congrats Chi Fung Willis Chow @swlenz.bsky.social et al. @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social doi.org/10.1002/pro....
Reposted by Toth-Petroczy lab
🍃CD-CODE update v1.09 is here!🍃
👀Check out the new #biomolecular #condensates at cd-code.org
👀We're continuing to update #Protein - #condensate connections and resolve issues!
Join us to share your #condensate #expertise as a contributor: cd-code.org/signup
#Bioinformatics #DatabaseUpdate #IDR
👀Check out the new #biomolecular #condensates at cd-code.org
👀We're continuing to update #Protein - #condensate connections and resolve issues!
Join us to share your #condensate #expertise as a contributor: cd-code.org/signup
#Bioinformatics #DatabaseUpdate #IDR
a group of ducklings are running in a field .
ALT: a group of ducklings are running in a field .
media.tenor.com
March 7, 2025 at 12:47 PM
🍃CD-CODE update v1.09 is here!🍃
👀Check out the new #biomolecular #condensates at cd-code.org
👀We're continuing to update #Protein - #condensate connections and resolve issues!
Join us to share your #condensate #expertise as a contributor: cd-code.org/signup
#Bioinformatics #DatabaseUpdate #IDR
👀Check out the new #biomolecular #condensates at cd-code.org
👀We're continuing to update #Protein - #condensate connections and resolve issues!
Join us to share your #condensate #expertise as a contributor: cd-code.org/signup
#Bioinformatics #DatabaseUpdate #IDR
Reposted by Toth-Petroczy lab
Programmable viscoelastic hydrogels uncover mechano-sensing timescales and direct cell polarity https://www.biorxiv.org/content/10.1101/2025.02.09.637331v1
February 10, 2025 at 3:46 AM
Programmable viscoelastic hydrogels uncover mechano-sensing timescales and direct cell polarity https://www.biorxiv.org/content/10.1101/2025.02.09.637331v1
Reposted by Toth-Petroczy lab
MPI-CBG director Anthony Hyman @hymanlab.bsky.social will deliver the EMBO Lecture at the 49th FEBS Congress in Istanbul in July 2025. Read an interview with him, where he shares some of his inspirations and interests. network.febs.org/posts/anthon...
Anthony Hyman: "...the realization of phase separation as a critical organizing principle in cellular biology has transformed the field."
From a 1920s book to nanoscopy – Anthony Hyman, who will deliver the EMBO Lecture at the 49th FEBS Congress in Istanbul in July 2025, shares some of his inspirations and interests.
network.febs.org
January 30, 2025 at 8:53 AM
MPI-CBG director Anthony Hyman @hymanlab.bsky.social will deliver the EMBO Lecture at the 49th FEBS Congress in Istanbul in July 2025. Read an interview with him, where he shares some of his inspirations and interests. network.febs.org/posts/anthon...
Great opportunity if you are looking for an interdisciplinary postdoctoral position 👇
Apply now for the ELBE Postdoctoral Fellows Program at the Center for Systems Biology @mpicbg.bsky.social @mpipks.bsky.social. The fully funded fellowships for postdoctoral researchers are designed for 2-3 years. Application deadline is February 14th. Join us! www.csbdresden.de/join-us/jobs...
January 29, 2025 at 7:55 AM
Great opportunity if you are looking for an interdisciplinary postdoctoral position 👇
Reposted by Toth-Petroczy lab
Machine learning algorithm, PICNIC, can predict which proteins are involved in biomolecular condensates, regardless of their structure. Publication in @natureportfolio.bsky.social Communications by the @tothpetroczylab.bsky.social & @hymanlab.bsky.social www.mpi-cbg.de/news-outreac...
December 13, 2024 at 10:28 AM
Machine learning algorithm, PICNIC, can predict which proteins are involved in biomolecular condensates, regardless of their structure. Publication in @natureportfolio.bsky.social Communications by the @tothpetroczylab.bsky.social & @hymanlab.bsky.social www.mpi-cbg.de/news-outreac...
Our PICNIC tool predicts condensate-proteins regardless of their structural disorder across organisms @naturecomms.bsky.social. Congratulations to @annaha-poetry-art.bsky.social for developing the algorithm and to Hari
@hymanlab.bsky.social for the experiments! www.nature.com/articles/s41...
@hymanlab.bsky.social for the experiments! www.nature.com/articles/s41...
PICNIC accurately predicts condensate-forming proteins regardless of their structural disorder across organisms - Nature Communications
Here the authors report PICNIC (Proteins Involved in CoNdensates In Cells), a machine learning algorithm that predicts approximately 40–60% of proteins form condensates in various organisms, showing n...
www.nature.com
December 12, 2024 at 8:27 PM
Our PICNIC tool predicts condensate-proteins regardless of their structural disorder across organisms @naturecomms.bsky.social. Congratulations to @annaha-poetry-art.bsky.social for developing the algorithm and to Hari
@hymanlab.bsky.social for the experiments! www.nature.com/articles/s41...
@hymanlab.bsky.social for the experiments! www.nature.com/articles/s41...
Reposted by Toth-Petroczy lab
✨Winter CD-CODE update to v1.08!✨
❄️ New #biomolecular #condensates added (total ⚪: 680)
❄️ #Protein - #condensate connections updated
❄️ Species attributes fixed 🤩
👀Check the current version here: cd-code.org
Join us to become a contributor: cd-code.org/signup
#DatabaseUpdate #Bioinformatics #IDR
❄️ New #biomolecular #condensates added (total ⚪: 680)
❄️ #Protein - #condensate connections updated
❄️ Species attributes fixed 🤩
👀Check the current version here: cd-code.org
Join us to become a contributor: cd-code.org/signup
#DatabaseUpdate #Bioinformatics #IDR
a row of penguins are walking in the snow
ALT: a row of penguins are walking in the snow
media.tenor.com
December 9, 2024 at 2:29 PM
✨Winter CD-CODE update to v1.08!✨
❄️ New #biomolecular #condensates added (total ⚪: 680)
❄️ #Protein - #condensate connections updated
❄️ Species attributes fixed 🤩
👀Check the current version here: cd-code.org
Join us to become a contributor: cd-code.org/signup
#DatabaseUpdate #Bioinformatics #IDR
❄️ New #biomolecular #condensates added (total ⚪: 680)
❄️ #Protein - #condensate connections updated
❄️ Species attributes fixed 🤩
👀Check the current version here: cd-code.org
Join us to become a contributor: cd-code.org/signup
#DatabaseUpdate #Bioinformatics #IDR
I am honored and excited to be part of the EMBO YIP!
Agnes Toth-Petroczy, research group leader @mpicbg.bsky.social and the Center for Systems Biology Dresden, becomes a member of the EMBO Young Investigator Programme. The program supports young group leaders in Europe and beyond. Congratulations! 🥳 www.mpi-cbg.de/news-outreac...
December 4, 2024 at 9:22 AM
I am honored and excited to be part of the EMBO YIP!