thomthum.bsky.social
@thomthum.bsky.social
Proud of Kaisa Pakari @kpakari.bsky.social to receive the 2025 Schmeil young researcher award for her #PhD thesis. She established 🐟 models to address disorders of #glycosylation #CDG by advancing #baseediting range for precise genome editing @wittbrodtlab.bsky.social @cos.uni-heidelberg.de
July 3, 2025 at 4:04 PM
Reposted
Are you in Germany in September (25th-27th) and ready to present your science? no further hesitation and register for the 15th GfE School on "Lineages: Revealing how Cells make Embryos and Tissues" at Schloss Reisensburg: www.vbio.de/gfe-entwickl... all #devbio enthusiasts and interested welcome!
June 24, 2025 at 11:45 PM
Reposted
LAST CHANCE TO REGISTER!

Calling all medaka researchers and enthusiasts!

Don't miss your chance to connect with the growing medaka community, share ideas, and spark new collaborations! The Medaka PI/ERC Indigene Meeting 2025 is just around the corner!

REGISTER NOW → meetmedaka.com
May 27, 2025 at 8:07 AM
new #preprint: mRNA delivered degron system w/ GFP-nanobody to efficiently reduce GFP-tagged proteins in an inducible manner in 🐟 Case study: reduction of PMM2 (basis for ER-based #glycosylation) causes hypoglycosylation reported from CDG-patients www.biorxiv.org/content/10.1... #CRISPR #RareDisease
Establishing an auxin-inducible GFP nanobody-based acute protein knockdown system to mimic hypomorphic mutations during early medaka embryogenesis
Creating hypomorphic mutations are crucial to study gene function in vivo, especially when null mutations result in (embryonic) lethality. This is especially the case for enzymes involved in glycosyla...
www.biorxiv.org
May 26, 2025 at 8:22 AM
Reposted
Happy to share our new preprint on lens morphogenesis in ocular organoids. All thanks to Elin Stahl, Miguel Angel Delgado-Toscano, Ishwariya Saravanan, Anastasija Paneva and Jochen Wittbrodt @wittbrodtlab.bsky.social

www.biorxiv.org/content/10.1...
April 23, 2025 at 9:19 PM
Reposted
New pre-print klaxon: "Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model" led by the excellent Bettina Welz + @saulpierotti.bsky.social from @wittbrodtlab.bsky.social, Felix Loosli, Kiyoshi Naruse and my own lab www.biorxiv.org/content/10.1...
Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model
Phenotypic variation arises from the interplay between genetic and environmental factors. However, disentangling these interactions for complex traits remains challenging in observational cohorts such...
www.biorxiv.org
April 28, 2025 at 3:17 PM
Register quickly and swim by! #medaka #meeting #conference
Calling all #MedakaPI researchers! Join us in Heidelberg, Germany from July 22-24, 2025 for our collaborative meeting! Register now & take advantage of early bird rates until April 15th! meetmedaka.com/registration/ 🐟 #MedakaResearch #ModelOrganisms #ScienceConference #FishModels #Heidelberg2025
April 7, 2025 at 1:39 PM