The Ott Lab
@theottlab.bsky.social
Melanie Ott's lab @ Gladstone Institutes studying host-viral pathogen interactions. Posts from lab members. Reposts are not endorsements.
The Gladstone Institute of Virology has taken on a new name: the Gladstone Infectious Disease Institute. Check it out here: gladstone.org/news/beyond-...
Beyond Viruses: Expanding the Fight Against Infectious Diseases
The newly renamed Gladstone Infectious Disease Institute broadens its mission to address global health threats ranging from antibiotic resistance to infections that cause chronic diseases.
gladstone.org
October 1, 2025 at 9:35 PM
The Gladstone Institute of Virology has taken on a new name: the Gladstone Infectious Disease Institute. Check it out here: gladstone.org/news/beyond-...
Check out Dr. Melanie Ott's recent opinion piece on the SF Standard: sfstandard.com/opinion/2025...
With vaccine research under attack, it’s time for California to lead again
Halting mRNA research right now is like banning ChatGPT, writes infectious disease expert Melanie Ott — not just scientific negligence, but strategic self-sabotage.
sfstandard.com
August 14, 2025 at 5:38 PM
Check out Dr. Melanie Ott's recent opinion piece on the SF Standard: sfstandard.com/opinion/2025...
Reposted by The Ott Lab
💉🧬 We're kicking off National Immunization Awareness Month with our faculty spotlight, Dr. Melanie Ott! Head to our Instagram to hear her take on how immunizations keep us safe—and how you can help to keep vaccines accessible for all: www.instagram.com/reel/DM_A9Sc...
@theottlab.bsky.social
@theottlab.bsky.social
August 5, 2025 at 7:24 PM
💉🧬 We're kicking off National Immunization Awareness Month with our faculty spotlight, Dr. Melanie Ott! Head to our Instagram to hear her take on how immunizations keep us safe—and how you can help to keep vaccines accessible for all: www.instagram.com/reel/DM_A9Sc...
@theottlab.bsky.social
@theottlab.bsky.social
Congratulations Fran! @franzapatero.bsky.social
Meet amfAR’s 2025 Mathilde Krim Fellows: Drs. Hastie, King, Ou & Zapatero Belinchon. As HIV research faces steep NIH cuts, amfAR is proud to back these bold young scientists and their innovative ideas. Learn more: www.amfar.org/news/new-amf...
amfAR Awards Boost Aspiring HIV Researchers
At a critical time for funding, amfAR awards four Mathilde Krim fellowships to early-career researchers studying innovative strategies to cure HIV.
www.amfar.org
July 29, 2025 at 5:51 PM
Congratulations Fran! @franzapatero.bsky.social
Congratulations to @juliaprigann.bsky.social for being awarded the 2025 CFAR Excellence in Basic/Translational Science Award!
cfar.ucsf.edu/user/11703
cfar.ucsf.edu/user/11703
Julia Prigann, PhD | UCSF-Bay Area Center for AIDS Research (CFAR)
cfar.ucsf.edu
July 17, 2025 at 5:16 PM
Congratulations to @juliaprigann.bsky.social for being awarded the 2025 CFAR Excellence in Basic/Translational Science Award!
cfar.ucsf.edu/user/11703
cfar.ucsf.edu/user/11703
We are delighted that we could help with this work. Check it out here: authors.elsevier.com/c/1lEffL7PXu...
authors.elsevier.com
June 11, 2025 at 5:41 PM
We are delighted that we could help with this work. Check it out here: authors.elsevier.com/c/1lEffL7PXu...
Reposted by The Ott Lab
Scientists from Gladstone and UCSF have developed drug candidates that could prevent future coronavirus pandemics.
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
Discovery Spotlight | Could This Molecule Be ‘Checkmate’ for Coronaviruses?
Scientists from Gladstone and UCSF have developed drug candidates that could prevent future coronavirus pandemics. These molecules block a critical enzyme ne...
www.youtube.com
April 29, 2025 at 1:18 PM
Scientists from Gladstone and UCSF have developed drug candidates that could prevent future coronavirus pandemics.
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
Reposted by The Ott Lab
Scientists develop powerful drug candidates that could head off future coronavirus pandemics.
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
Could This Molecule Be ‘Checkmate’ for Coronaviruses?
Scientists develop powerful drug candidates that could head off future coronavirus pandemics.
gladstone.org
April 23, 2025 at 8:54 PM
Scientists develop powerful drug candidates that could head off future coronavirus pandemics.
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
Reposted by The Ott Lab
🚨 NEW PUBLICATION 🚨 "Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy"
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy
This study describes a class of potent, bioavailable SARS-CoV-2 MPro inhibitors having an unusual mechanism of inhibition.
www.science.org
April 24, 2025 at 3:02 PM
🚨 NEW PUBLICATION 🚨 "Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy"
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
@theottlab.bsky.social
@ucsfmedicine.bsky.social
@qbi-ucsf.bsky.social
Reposted by The Ott Lab
🎧 Listen to this podcast featuring virologist Melanie Ott. Ott discusses how measles works and the way it breaks into our body to make us sick.
@theottlab.bsky.social
@theottlab.bsky.social
How does measles make us sick?
And the damage left in its wake...
bit.ly
April 10, 2025 at 1:18 PM
🎧 Listen to this podcast featuring virologist Melanie Ott. Ott discusses how measles works and the way it breaks into our body to make us sick.
@theottlab.bsky.social
@theottlab.bsky.social
Thank you to everyone who attended the HIV Mini-Symposium on March 13th!
Our next Mini-Symposium will be September 23, 2025 titled 'Viral Landscapes: How to Comprehensively Monitor Evolutionary Trajectories'. We hope to see you there!
www.youtube.com/watch?v=vjpe...
Our next Mini-Symposium will be September 23, 2025 titled 'Viral Landscapes: How to Comprehensively Monitor Evolutionary Trajectories'. We hope to see you there!
www.youtube.com/watch?v=vjpe...
HIV Persistence: Where We Are Now and Where We Need to Go
YouTube video by QBI TV
www.youtube.com
March 28, 2025 at 4:30 PM
Thank you to everyone who attended the HIV Mini-Symposium on March 13th!
Our next Mini-Symposium will be September 23, 2025 titled 'Viral Landscapes: How to Comprehensively Monitor Evolutionary Trajectories'. We hope to see you there!
www.youtube.com/watch?v=vjpe...
Our next Mini-Symposium will be September 23, 2025 titled 'Viral Landscapes: How to Comprehensively Monitor Evolutionary Trajectories'. We hope to see you there!
www.youtube.com/watch?v=vjpe...
Reposted by The Ott Lab
Did you know that viruses don’t just infect humans—they also target bacteria in our microbiome? These viruses, called phages, play a crucial role in shaping our health and could be the key to fighting antibiotic-resistant bacteria.
In this short, @theottlab.bsky.social explains.
In this short, @theottlab.bsky.social explains.
March 26, 2025 at 1:20 PM
Did you know that viruses don’t just infect humans—they also target bacteria in our microbiome? These viruses, called phages, play a crucial role in shaping our health and could be the key to fighting antibiotic-resistant bacteria.
In this short, @theottlab.bsky.social explains.
In this short, @theottlab.bsky.social explains.
Reposted by The Ott Lab
Virologist Melanie Ott (@theottlab.bsky.social) speaks to KUSI News about the measles outbreak and other infectious diseases.
Gladstone's Dr. Melanie Ott speaks about measles, other infectious diseases on KUSI
buff.ly
March 20, 2025 at 1:18 PM
Virologist Melanie Ott (@theottlab.bsky.social) speaks to KUSI News about the measles outbreak and other infectious diseases.
Reposted by The Ott Lab
At Gladstone, researchers are working toward curing HIV for good. Their work also sheds light on how viruses influence our long-term health. Melanie Ott, MD, PhD, director of the Gladstone Institute of Virology explains why curing HIV remains a crucial scientific challenge.
@theottlab.bsky.social
@theottlab.bsky.social
March 19, 2025 at 2:19 PM
At Gladstone, researchers are working toward curing HIV for good. Their work also sheds light on how viruses influence our long-term health. Melanie Ott, MD, PhD, director of the Gladstone Institute of Virology explains why curing HIV remains a crucial scientific challenge.
@theottlab.bsky.social
@theottlab.bsky.social
Reposted by The Ott Lab
What does the bird flu outbreak mean for public health? Virologist Melanie Ott (@theottlab.bsky.social) discusses how H5N1 in cows could affect virus evolution and why increased surveillance is important.
How Bird Flu in Cows Could Impact Public Health | Melanie Ott Explains
What does the bird flu outbreak mean for public health? Melanie Ott, MD, PhD, director of the Gladstone Institute of Virology, discusses how H5N1 in cows cou...
youtube.com
March 14, 2025 at 1:18 PM
What does the bird flu outbreak mean for public health? Virologist Melanie Ott (@theottlab.bsky.social) discusses how H5N1 in cows could affect virus evolution and why increased surveillance is important.
Reposted by The Ott Lab
Melanie Ott talks about the ongoing measles outbreak, explains how vaccination can lower the risk of Alzheimer’s, and shares other positive “side effects” of vaccines.
@theottlab.bsky.social
@theottlab.bsky.social
Virologist Viewpoints: The Positive Side Effects of Vaccines
Melanie Ott talks about the ongoing measles outbreak, explains how vaccination can lower the risk of Alzheimer’s, and shares other positive “side effects” of vaccines.
gladstone.org
March 13, 2025 at 6:30 PM
Melanie Ott talks about the ongoing measles outbreak, explains how vaccination can lower the risk of Alzheimer’s, and shares other positive “side effects” of vaccines.
@theottlab.bsky.social
@theottlab.bsky.social
Reposted by The Ott Lab
In an interview with @amfarofficial.bsky.social, Melanie Ott (@theottlab.bsky.social), discusses the future of HIV research, and describes how lessons from the field have laid a strong foundation for fighting other viral diseases.
Shaping the Future of HIV Research
amfAR interviewed Gladstone Institutes’ Dr. Melanie Ott about her work on HIV, hepatitis C, and other viruses, and the promise of new technologies.
www.amfar.org
March 12, 2025 at 9:18 PM
In an interview with @amfarofficial.bsky.social, Melanie Ott (@theottlab.bsky.social), discusses the future of HIV research, and describes how lessons from the field have laid a strong foundation for fighting other viral diseases.
Reposted by The Ott Lab
Gladstone recently hosted the German Center for Research and Innovation San Francisco for their Innovation Summit. The event addressed the challenge of sharing data across sectors, institutions, and borders, a key question for global health. Speakers included Melanie Ott (@theottlab.bsky.social)
March 7, 2025 at 2:18 PM
Gladstone recently hosted the German Center for Research and Innovation San Francisco for their Innovation Summit. The event addressed the challenge of sharing data across sectors, institutions, and borders, a key question for global health. Speakers included Melanie Ott (@theottlab.bsky.social)
Reposted by The Ott Lab
HIV research has led to breakthroughs in antiviral treatments & cancer therapies. amfAR’s Dr. Andrea Gramatica & Dr. Melanie Ott (@theottlab.bsky.social) discuss how investing in one virus drives medical innovation. www.amfar.org/news/shaping...
Shaping the Future of HIV
amfAR interviewed Gladstone Institutes’ Dr. Melanie Ott about her work on HIV, hepatitis C, and other viruses, and the promise of new technologies.
www.amfar.org
March 5, 2025 at 9:09 PM
HIV research has led to breakthroughs in antiviral treatments & cancer therapies. amfAR’s Dr. Andrea Gramatica & Dr. Melanie Ott (@theottlab.bsky.social) discuss how investing in one virus drives medical innovation. www.amfar.org/news/shaping...
Please join us at our mini-symposium on the latest advancements in HIV persistence next week. gladstone.org/events/hiv-p... via @gladstoneinst.bsky.social
HIV Persistence: Where We Are Now and Where We Need to Go
Mini-symposium series on the latest advancements in HIV persistence.
gladstone.org
March 4, 2025 at 6:59 PM
Please join us at our mini-symposium on the latest advancements in HIV persistence next week. gladstone.org/events/hiv-p... via @gladstoneinst.bsky.social
Yesterday we hosted the German Consulate and the German Research Foundation for their Global Innovation Summit at @gladstoneinst.bsky.social Thank you to everyone involved!
Photos by © Barak Shrama
Photos by © Barak Shrama
March 1, 2025 at 12:24 AM
Yesterday we hosted the German Consulate and the German Research Foundation for their Global Innovation Summit at @gladstoneinst.bsky.social Thank you to everyone involved!
Photos by © Barak Shrama
Photos by © Barak Shrama
Melanie Ott talks to Newsweek about the risk of bird flu from drinking milk. Check it out!
www.newsweek.com/can-you-get-...
www.newsweek.com/can-you-get-...
Can you get bird flu from drinking milk? What to know as cows are infected
Consumers can safely drink pasteurized milk, despite reports of dairy cattle infected with the new strain of bird flu.
www.newsweek.com
February 21, 2025 at 8:47 PM
Melanie Ott talks to Newsweek about the risk of bird flu from drinking milk. Check it out!
www.newsweek.com/can-you-get-...
www.newsweek.com/can-you-get-...
Reposted by The Ott Lab
Our CEO, Eric Verdin answered questions about the administration’s proposed budget cuts to the NIH at a hearing before the Senate Special Committee on Aging this afternoon. Hear his exchange with Angela Alsobrook D-MD here: youtu.be/XrhHldez1AI
Eric Verdin, MD, President of the Buck Institute in hearing of the Senate Special Committee on Aging
YouTube video by Buck Institute for Research on Aging
youtu.be
February 13, 2025 at 2:03 AM
Our CEO, Eric Verdin answered questions about the administration’s proposed budget cuts to the NIH at a hearing before the Senate Special Committee on Aging this afternoon. Hear his exchange with Angela Alsobrook D-MD here: youtu.be/XrhHldez1AI
Reposted by The Ott Lab
Gladstone virologist Melanie Ott talks to Salon about the #BirdFlu. Read more to learn how you can best understand and manage your risk.
Your questions about bird flu answered by experts
H5N1 isn’t going away anytime soon and could become a pandemic. Here are some tips to help you understand your risk
buff.ly
February 16, 2025 at 2:18 PM
Gladstone virologist Melanie Ott talks to Salon about the #BirdFlu. Read more to learn how you can best understand and manage your risk.
Reposted by The Ott Lab
Interesting bioRxiv preprint by a team around Charles Craik, Adam Renslo and @theottlab.bsky.social. Inhibitors for Mpro of coronaviruses based on a dihydrouracil chemotype and a propargyl amide warhead as reactive group to engage the catalytic cysteine. #chemsky #ChemBio www.biorxiv.org/cont...
January 22, 2025 at 3:00 PM
Interesting bioRxiv preprint by a team around Charles Craik, Adam Renslo and @theottlab.bsky.social. Inhibitors for Mpro of coronaviruses based on a dihydrouracil chemotype and a propargyl amide warhead as reactive group to engage the catalytic cysteine. #chemsky #ChemBio www.biorxiv.org/cont...