Alexandra Nicaise
@telencephale.bsky.social
Incoming assistant professor @UAMS
Neural stem cells & the choroid plexus in neuroinflammation using patient-based 2D and 3D models
Senior Research Associate, Dept of Clinical Neurosciences, University of Cambridge
Neural stem cells & the choroid plexus in neuroinflammation using patient-based 2D and 3D models
Senior Research Associate, Dept of Clinical Neurosciences, University of Cambridge
Pinned
Excited to see our work published in @cp-neuron.bsky.social !
Reposted by Alexandra Nicaise
Endothelial gateways for brain lipid uptake and metabolism: www.jci.org/articles/vie...
A. Dushani Ranasinghe & Timothy Hla Comment on Wenxin Song et al: www.jci.org/articles/vie...
A. Dushani Ranasinghe & Timothy Hla Comment on Wenxin Song et al: www.jci.org/articles/vie...
October 10, 2025 at 4:16 PM
Endothelial gateways for brain lipid uptake and metabolism: www.jci.org/articles/vie...
A. Dushani Ranasinghe & Timothy Hla Comment on Wenxin Song et al: www.jci.org/articles/vie...
A. Dushani Ranasinghe & Timothy Hla Comment on Wenxin Song et al: www.jci.org/articles/vie...
Reposted by Alexandra Nicaise
How can mitophagy be an effective quality control mechanism if mtDNA mutations reach high enough levels to cause disease?
This question led us into a dark path, full of concepts of evolutionary genetics, germline stem cell biology and mito-nuclear compatibility.
www.science.org/doi/10.1126/...
This question led us into a dark path, full of concepts of evolutionary genetics, germline stem cell biology and mito-nuclear compatibility.
www.science.org/doi/10.1126/...
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
Mitochondrial synthesis of adenosine triphosphate is essential for eukaryotic life but is dependent on the cooperation of two genomes: nuclear and mitochondrial DNA (mtDNA). mtDNA mutates ~15 times as...
www.science.org
October 10, 2025 at 8:45 AM
How can mitophagy be an effective quality control mechanism if mtDNA mutations reach high enough levels to cause disease?
This question led us into a dark path, full of concepts of evolutionary genetics, germline stem cell biology and mito-nuclear compatibility.
www.science.org/doi/10.1126/...
This question led us into a dark path, full of concepts of evolutionary genetics, germline stem cell biology and mito-nuclear compatibility.
www.science.org/doi/10.1126/...
Excited to see our work published in @cp-neuron.bsky.social !
October 12, 2025 at 9:45 AM
Excited to see our work published in @cp-neuron.bsky.social !
