Takashi Ochi (Leeds)
@takashiochi.bsky.social
Group leader @ University of Leeds interested in protein structures, centrosomal/ciliary biology and DSB repair in plants, and love coffee/whisky/cycling/vinyls. Views my own.
www.nature.com/articles/s41...
Interstasis, an impressive discovery! It kind of explains some of the odd behaviours of CCDC61, which can actually crystallise in cells when it’s overexpressed. It is a liquid-solid phase separation….
Interstasis, an impressive discovery! It kind of explains some of the odd behaviours of CCDC61, which can actually crystallise in cells when it’s overexpressed. It is a liquid-solid phase separation….
Collective homeostasis of condensation-prone proteins via their mRNAs - Nature
The authors discover a homeostatic process termed interstasis, in which an increased concentration of proteins within RNA–protein condensates induces the sequestration of their own mRNAs.
www.nature.com
September 27, 2025 at 4:55 PM
www.nature.com/articles/s41...
Interstasis, an impressive discovery! It kind of explains some of the odd behaviours of CCDC61, which can actually crystallise in cells when it’s overexpressed. It is a liquid-solid phase separation….
Interstasis, an impressive discovery! It kind of explains some of the odd behaviours of CCDC61, which can actually crystallise in cells when it’s overexpressed. It is a liquid-solid phase separation….
Chlamy Hello Kitty at the Japan Pavilion Osaka Expo 2025
August 8, 2025 at 9:53 AM
Chlamy Hello Kitty at the Japan Pavilion Osaka Expo 2025
Reposted by Takashi Ochi (Leeds)
It's finally out in @cp-molcell.bsky.social. Huge thanks to @leneyms.bsky.social and team Morris @themorrislab.bsky.social for getting this SUMO4 story over the finish line!
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair: Molecular Cell www.cell.com/molecular-ce...
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair: Molecular Cell www.cell.com/molecular-ce...
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
Garvin et al. find that the poorly explored SUMO isoform, SUMO4, enhances the deSUMOylation
activity of the SUMO protease SENP1. Consequently, SUMO4 acts to restrain excessive
cellular SUMOylation. In...
www.cell.com
March 13, 2025 at 2:30 PM
It's finally out in @cp-molcell.bsky.social. Huge thanks to @leneyms.bsky.social and team Morris @themorrislab.bsky.social for getting this SUMO4 story over the finish line!
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair: Molecular Cell www.cell.com/molecular-ce...
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair: Molecular Cell www.cell.com/molecular-ce...
Reposted by Takashi Ochi (Leeds)
A reminder that the Brown lab has an opening for a postdoc fellow: brown.hms.harvard.edu/jobs/242. This might suit someone from the #cilia community interested in learning structural biology. Deadline extended to the 10th Jan.
Postdoctoral fellow | Brown Lab
The Brown lab at Harvard Medical School is seeking a highly motivated postdoctoral fellow to join our team.
brown.hms.harvard.edu
January 2, 2025 at 3:18 PM
A reminder that the Brown lab has an opening for a postdoc fellow: brown.hms.harvard.edu/jobs/242. This might suit someone from the #cilia community interested in learning structural biology. Deadline extended to the 10th Jan.
Reposted by Takashi Ochi (Leeds)
In Feb 2025 we will host a Virtual Wellcome - Advanced SPA Cryo-EM Course.
The course will be for PhD student, postdoc, staff scientist or young group leaders.
If you think it will benefit you go to the website for more info: astbury.leeds.ac.uk/facilities/w...
Sharing will be appreciated :-)
The course will be for PhD student, postdoc, staff scientist or young group leaders.
If you think it will benefit you go to the website for more info: astbury.leeds.ac.uk/facilities/w...
Sharing will be appreciated :-)
Advanced Single Particle Cryo-EM Course – February 2025 : The Astbury Centre for Structural Molecular Biology
Course overview The course is a part of the Wellcome Trust and MRC funded Cryo-EM Training Program that offers an intensive learning opportunity tailored to PhD students, postdocs, and early-career sc...
astbury.leeds.ac.uk
December 11, 2024 at 1:25 PM
In Feb 2025 we will host a Virtual Wellcome - Advanced SPA Cryo-EM Course.
The course will be for PhD student, postdoc, staff scientist or young group leaders.
If you think it will benefit you go to the website for more info: astbury.leeds.ac.uk/facilities/w...
Sharing will be appreciated :-)
The course will be for PhD student, postdoc, staff scientist or young group leaders.
If you think it will benefit you go to the website for more info: astbury.leeds.ac.uk/facilities/w...
Sharing will be appreciated :-)
Reposted by Takashi Ochi (Leeds)
We have a very cool (I know I am biased😁) project for a computational biologist (postdoc) interested in cancer evolution in collaboration with Nicky McGranahan’s lab! Perfect opportunity to expand your computational skills too!
👉 www.godinholab.com
RT please 🙏🙏🙏👍👍
👉 www.godinholab.com
RT please 🙏🙏🙏👍👍
Godinho Lab
www.godinholab.com
December 11, 2024 at 4:01 PM
We have a very cool (I know I am biased😁) project for a computational biologist (postdoc) interested in cancer evolution in collaboration with Nicky McGranahan’s lab! Perfect opportunity to expand your computational skills too!
👉 www.godinholab.com
RT please 🙏🙏🙏👍👍
👉 www.godinholab.com
RT please 🙏🙏🙏👍👍
Reposted by Takashi Ochi (Leeds)
Delighted to be advertising 2 exciting PhD projects 1) lncRNA derived micropeptides & their contribution to brain cancers with James Poulter & Lucy Stead 2) mechanisms of translational regulation by specialised ribosomes. @chillzaa.bsky.social & Ade Whitehouse www.findaphd.com/phds/?Keywor...
aspden PhD Projects, Programmes & Scholarships
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in aspden. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
www.findaphd.com
November 26, 2024 at 5:05 PM
Delighted to be advertising 2 exciting PhD projects 1) lncRNA derived micropeptides & their contribution to brain cancers with James Poulter & Lucy Stead 2) mechanisms of translational regulation by specialised ribosomes. @chillzaa.bsky.social & Ade Whitehouse www.findaphd.com/phds/?Keywor...
Reposted by Takashi Ochi (Leeds)
Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology
Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...
www.nature.com
November 18, 2024 at 11:06 AM
Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Fantastic meeting with a great memorial talk for David Stephens by Anthony Roberts. There were also many stimulating talks by ECRs and Elif Nur Firat-Karalar. Thanks for @urszulamcclurg.bsky.social for organising this event in Liverpool!
We opened our @ukcilianetwork.bsky.social Autumn symposium in Liverpool with a beautiful memorial plenary for David Stephens by long time collaborator Anthony Roberts @dunnschool.bsky.social on his huge influence on shaping cell science, careers & research culture. /1
November 23, 2024 at 9:06 AM
Fantastic meeting with a great memorial talk for David Stephens by Anthony Roberts. There were also many stimulating talks by ECRs and Elif Nur Firat-Karalar. Thanks for @urszulamcclurg.bsky.social for organising this event in Liverpool!
Funded PhD structural plant biology project focusing on understanding DNA double-strand break repair in plants! This project is a part of the Yorkshire Bioscience Doctoral Training Partnership and in collaboration with Chris West (Leeds).
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Structural studies of DNA double-strand break repair in plants at University of Leeds on FindAPhD.com
PhD Project - Structural studies of DNA double-strand break repair in plants at University of Leeds, listed on FindAPhD.com
www.findaphd.com
November 21, 2024 at 6:49 PM
Funded PhD structural plant biology project focusing on understanding DNA double-strand break repair in plants! This project is a part of the Yorkshire Bioscience Doctoral Training Partnership and in collaboration with Chris West (Leeds).
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by Takashi Ochi (Leeds)
I am about to be recruiting two post-docs to work on cryoEM and cryoET of amyloid aggregates... Anyone interested please drop me a line while the wheels of our HR department turn.............
November 18, 2024 at 3:09 PM
I am about to be recruiting two post-docs to work on cryoEM and cryoET of amyloid aggregates... Anyone interested please drop me a line while the wheels of our HR department turn.............