Synlett Journal
@synlettjournal.bsky.social
An international, peer-reviewed #Account and #Letter journal from Thieme reporting research results and current trends in #chemicalsynthesis.
🔗 https://www.thieme.de/de/synlett/journal-information-55964.htm
🔗 https://www.thieme.de/de/synlett/journal-information-55964.htm
Pinned
Are you an innovator in #ChemicalSynthesis? Find your audience with SYNLETT!
Why SYNLETT:
👥 Rapid Select Crowd Review
🤝 Support for Early Career Researchers
💡 Diverse Editorial Board
...and more!
Submit today: buff.ly/2q3gEkL
Why SYNLETT:
👥 Rapid Select Crowd Review
🤝 Support for Early Career Researchers
💡 Diverse Editorial Board
...and more!
Submit today: buff.ly/2q3gEkL
Reposted by Synlett Journal
Congratulations to Kevin, Andy and Will on their @synlettjournal.bsky.social paper! www.thieme-connect.com/products/ejo...
February 11, 2026 at 3:10 PM
Congratulations to Kevin, Andy and Will on their @synlettjournal.bsky.social paper! www.thieme-connect.com/products/ejo...
Light-driven radical chemistry in action✨ A systematic study by Samuel Oger & Gwilherm Evano shows that sulfonamides undergo exclusive exo-dig cyclization under Cu- #photoredox conditions, giving access to azetidines, pyrrolidines, piperidines & azepanes 🔬
#copper
👉 buff.ly/Wsuwss4
#copper
👉 buff.ly/Wsuwss4
February 11, 2026 at 8:01 AM
Light-driven radical chemistry in action✨ A systematic study by Samuel Oger & Gwilherm Evano shows that sulfonamides undergo exclusive exo-dig cyclization under Cu- #photoredox conditions, giving access to azetidines, pyrrolidines, piperidines & azepanes 🔬
#copper
👉 buff.ly/Wsuwss4
#copper
👉 buff.ly/Wsuwss4
Eight years of light-driven #nickel catalysis💡Bartholomäus Pieber traces the journey from reusable carbon nitride photocatalysts to dye-sensitized metallaphotocatalysts, COFs, and tailored conjugated polymers⚗️
#photocatalysis
👉 buff.ly/3pFrKdG
#photocatalysis
👉 buff.ly/3pFrKdG
February 9, 2026 at 8:01 AM
Eight years of light-driven #nickel catalysis💡Bartholomäus Pieber traces the journey from reusable carbon nitride photocatalysts to dye-sensitized metallaphotocatalysts, COFs, and tailored conjugated polymers⚗️
#photocatalysis
👉 buff.ly/3pFrKdG
#photocatalysis
👉 buff.ly/3pFrKdG
Building quaternary carbons with #nickel 🔬 Wang & Shi report a Ni-catalyzed, Markovnikov-selective addition of #organoborons to simple alkenes using a diimine ligand, enabling high-yield access to all-carbon quaternary centers. Bulky chiral ligands also allow stereocontrol⚗️
👉 buff.ly/6lAlzvq
👉 buff.ly/6lAlzvq
February 6, 2026 at 8:01 AM
Building quaternary carbons with #nickel 🔬 Wang & Shi report a Ni-catalyzed, Markovnikov-selective addition of #organoborons to simple alkenes using a diimine ligand, enabling high-yield access to all-carbon quaternary centers. Bulky chiral ligands also allow stereocontrol⚗️
👉 buff.ly/6lAlzvq
👉 buff.ly/6lAlzvq
Green synthesis of #atropisomers 🌿Christian Wolf & co-workers report a base-promoted Csp²–Csp³ bond formation between #fluorooxindoles and 4-chloro-3-nitrocoumarins, yielding atropisomeric structures with high diastereoselectivity in just 1 h at rt💡
#coumarins
👉 buff.ly/TKGV0ok
#coumarins
👉 buff.ly/TKGV0ok
February 4, 2026 at 8:01 AM
Green synthesis of #atropisomers 🌿Christian Wolf & co-workers report a base-promoted Csp²–Csp³ bond formation between #fluorooxindoles and 4-chloro-3-nitrocoumarins, yielding atropisomeric structures with high diastereoselectivity in just 1 h at rt💡
#coumarins
👉 buff.ly/TKGV0ok
#coumarins
👉 buff.ly/TKGV0ok
#Ruthenium to the rescue🧬Bhatia @rohitbhatia10.bsky.social Singh & co-workers highlight Ru-based anticancer agents as promising alternatives to traditional platinum drugs💊, offering lower toxicity, potent anticancer/anti-metastatic activity, and precise control⚡
👉 buff.ly/LPZJ4iX
👉 buff.ly/LPZJ4iX
February 2, 2026 at 8:01 AM
#Ruthenium to the rescue🧬Bhatia @rohitbhatia10.bsky.social Singh & co-workers highlight Ru-based anticancer agents as promising alternatives to traditional platinum drugs💊, offering lower toxicity, potent anticancer/anti-metastatic activity, and precise control⚡
👉 buff.ly/LPZJ4iX
👉 buff.ly/LPZJ4iX
✨Cluster: 'Small Molecules in Medicinal Chemistry'✨
Advancing NSCLC therapy💊Udit Chaube reviews mTOR #inhibitors like RM-018 & RMC-4998 targeting KRASG12C mutations, along with plant-derived compounds showing potent antitumor activity 🧬
#cancer
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
Advancing NSCLC therapy💊Udit Chaube reviews mTOR #inhibitors like RM-018 & RMC-4998 targeting KRASG12C mutations, along with plant-derived compounds showing potent antitumor activity 🧬
#cancer
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
January 30, 2026 at 8:01 AM
✨Cluster: 'Small Molecules in Medicinal Chemistry'✨
Advancing NSCLC therapy💊Udit Chaube reviews mTOR #inhibitors like RM-018 & RMC-4998 targeting KRASG12C mutations, along with plant-derived compounds showing potent antitumor activity 🧬
#cancer
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
Advancing NSCLC therapy💊Udit Chaube reviews mTOR #inhibitors like RM-018 & RMC-4998 targeting KRASG12C mutations, along with plant-derived compounds showing potent antitumor activity 🧬
#cancer
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
Turning alkenes into chiral building blocks✨Wanderley & Crisenza showcase how #electrosynthesis is revolutionizing asymmetric 1,2-difunctionalization. Their “Sew & Cut” strategy merges pericyclic 1,3-dipolar cycloadditions with radical reactivity for complexity generation🧪
👉 buff.ly/gmBJTl3
👉 buff.ly/gmBJTl3
January 28, 2026 at 8:01 AM
Turning alkenes into chiral building blocks✨Wanderley & Crisenza showcase how #electrosynthesis is revolutionizing asymmetric 1,2-difunctionalization. Their “Sew & Cut” strategy merges pericyclic 1,3-dipolar cycloadditions with radical reactivity for complexity generation🧪
👉 buff.ly/gmBJTl3
👉 buff.ly/gmBJTl3
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
Unnatural amino acids are privileged scaffolds in drug discovery. Keisuke Tomohara & co-workers present a new Account detailing efficient synthetic routes using readily accessible building blocks🧪
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
Unnatural amino acids are privileged scaffolds in drug discovery. Keisuke Tomohara & co-workers present a new Account detailing efficient synthetic routes using readily accessible building blocks🧪
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
January 26, 2026 at 8:01 AM
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
Unnatural amino acids are privileged scaffolds in drug discovery. Keisuke Tomohara & co-workers present a new Account detailing efficient synthetic routes using readily accessible building blocks🧪
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
Unnatural amino acids are privileged scaffolds in drug discovery. Keisuke Tomohara & co-workers present a new Account detailing efficient synthetic routes using readily accessible building blocks🧪
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
Dobrydnev & team have developed a simple, scalable way to synthesize unknown heterocyclic systems🧪By using intramolecular cyclization, they’ve unlocked effortless access to complex keto sulfoximines
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
Dobrydnev & team have developed a simple, scalable way to synthesize unknown heterocyclic systems🧪By using intramolecular cyclization, they’ve unlocked effortless access to complex keto sulfoximines
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
January 23, 2026 at 8:01 AM
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
Dobrydnev & team have developed a simple, scalable way to synthesize unknown heterocyclic systems🧪By using intramolecular cyclization, they’ve unlocked effortless access to complex keto sulfoximines
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
Dobrydnev & team have developed a simple, scalable way to synthesize unknown heterocyclic systems🧪By using intramolecular cyclization, they’ve unlocked effortless access to complex keto sulfoximines
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
How have small-molecule drugs evolved over the last decade?🧪 Singh, Mahindroo & team examine how pharmacophore-based design is transforming treatment for rare diseases and neurological conditions🧬
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
How have small-molecule drugs evolved over the last decade?🧪 Singh, Mahindroo & team examine how pharmacophore-based design is transforming treatment for rare diseases and neurological conditions🧬
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
January 21, 2026 at 8:01 AM
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
How have small-molecule drugs evolved over the last decade?🧪 Singh, Mahindroo & team examine how pharmacophore-based design is transforming treatment for rare diseases and neurological conditions🧬
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
How have small-molecule drugs evolved over the last decade?🧪 Singh, Mahindroo & team examine how pharmacophore-based design is transforming treatment for rare diseases and neurological conditions🧬
#OpenAccess for a limited time 👉 buff.ly/JY1Qe2E
Harnessing #electrocatalysis for greener chemistry🌱Dapkekar & Satyanarayana showcase their lab’s advances in electro-organic synthesis, from 3° alcohols to spiro-cyclohexadienone indenes, β-hydroxy-selenides & more, all without hazardous oxidants/reductants⚗️
👉 buff.ly/zwFhEEQ
👉 buff.ly/zwFhEEQ
January 19, 2026 at 8:00 AM
Harnessing #electrocatalysis for greener chemistry🌱Dapkekar & Satyanarayana showcase their lab’s advances in electro-organic synthesis, from 3° alcohols to spiro-cyclohexadienone indenes, β-hydroxy-selenides & more, all without hazardous oxidants/reductants⚗️
👉 buff.ly/zwFhEEQ
👉 buff.ly/zwFhEEQ
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
Unlock the #proteome with succinimide-containing probes🧪 Developed by William Parsons & co-workers, these new reactive groups are expanding how we study #enzyme activity
#OpenAccess 👉 www.thieme-connect.com/products/ejo...
Unlock the #proteome with succinimide-containing probes🧪 Developed by William Parsons & co-workers, these new reactive groups are expanding how we study #enzyme activity
#OpenAccess 👉 www.thieme-connect.com/products/ejo...
January 16, 2026 at 8:01 AM
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
Unlock the #proteome with succinimide-containing probes🧪 Developed by William Parsons & co-workers, these new reactive groups are expanding how we study #enzyme activity
#OpenAccess 👉 www.thieme-connect.com/products/ejo...
Unlock the #proteome with succinimide-containing probes🧪 Developed by William Parsons & co-workers, these new reactive groups are expanding how we study #enzyme activity
#OpenAccess 👉 www.thieme-connect.com/products/ejo...
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
New insights from MacQueen & Billingsley on #indolactam alkaloids🧬 Discover how these potent activators are being optimized for #tumor suppression💊
#OpenAccess for a limited time 👉 buff.ly/9k3tcQa
New insights from MacQueen & Billingsley on #indolactam alkaloids🧬 Discover how these potent activators are being optimized for #tumor suppression💊
#OpenAccess for a limited time 👉 buff.ly/9k3tcQa
January 14, 2026 at 8:01 AM
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
New insights from MacQueen & Billingsley on #indolactam alkaloids🧬 Discover how these potent activators are being optimized for #tumor suppression💊
#OpenAccess for a limited time 👉 buff.ly/9k3tcQa
New insights from MacQueen & Billingsley on #indolactam alkaloids🧬 Discover how these potent activators are being optimized for #tumor suppression💊
#OpenAccess for a limited time 👉 buff.ly/9k3tcQa
Reposted by Synlett Journal
We’re live!
Introducing Therapeutics NOW – Thieme’s new Gold Open Access journal driving breakthroughs in translational therapeutic research.
✅ Interdisciplinary by design
✅ Broad scope & impactful article formats
✅ Ultra-fast peer review via Select Crowd Review
🔗 www.thieme.com/en-us/thieme...
Introducing Therapeutics NOW – Thieme’s new Gold Open Access journal driving breakthroughs in translational therapeutic research.
✅ Interdisciplinary by design
✅ Broad scope & impactful article formats
✅ Ultra-fast peer review via Select Crowd Review
🔗 www.thieme.com/en-us/thieme...
Thieme Launches New Open Access Journal Therapeutics NOW
Thieme Launches New Open Access Journal Therapeutics NOW Stuttgart, January 2026 – Thieme is expanding its open access portfolio to promote evidence-based therapeutic development. Therapeutics NOW wil...
www.thieme.com
January 12, 2026 at 11:31 AM
We’re live!
Introducing Therapeutics NOW – Thieme’s new Gold Open Access journal driving breakthroughs in translational therapeutic research.
✅ Interdisciplinary by design
✅ Broad scope & impactful article formats
✅ Ultra-fast peer review via Select Crowd Review
🔗 www.thieme.com/en-us/thieme...
Introducing Therapeutics NOW – Thieme’s new Gold Open Access journal driving breakthroughs in translational therapeutic research.
✅ Interdisciplinary by design
✅ Broad scope & impactful article formats
✅ Ultra-fast peer review via Select Crowd Review
🔗 www.thieme.com/en-us/thieme...
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
Dive into the future of #cancer therapy with the discovery of a novel TRK-selective inhibitor🧬 This next-gen candidate by Ito & co-workers offers high selectivity and reduced drug interaction risks💊
#OpenAccess for a limited time 👉 buff.ly/IVHXIb3
Dive into the future of #cancer therapy with the discovery of a novel TRK-selective inhibitor🧬 This next-gen candidate by Ito & co-workers offers high selectivity and reduced drug interaction risks💊
#OpenAccess for a limited time 👉 buff.ly/IVHXIb3
January 12, 2026 at 8:01 AM
✨Cluster 'Small Molecules in Medicinal Chemistry'✨
Dive into the future of #cancer therapy with the discovery of a novel TRK-selective inhibitor🧬 This next-gen candidate by Ito & co-workers offers high selectivity and reduced drug interaction risks💊
#OpenAccess for a limited time 👉 buff.ly/IVHXIb3
Dive into the future of #cancer therapy with the discovery of a novel TRK-selective inhibitor🧬 This next-gen candidate by Ito & co-workers offers high selectivity and reduced drug interaction risks💊
#OpenAccess for a limited time 👉 buff.ly/IVHXIb3
Green chemistry meets bioactive scaffolds🌱 S. Chaudhuri & co-workers use CBr₄ as a metal-free catalyst for regioselective synthesis of #dihydrochromenoindole fused heterocycles. Scalable, reproducible & bioactive, streamlined synthesis with minimal side reactions🔬
👉 buff.ly/2JUiwKe
👉 buff.ly/2JUiwKe
January 9, 2026 at 8:01 AM
Green chemistry meets bioactive scaffolds🌱 S. Chaudhuri & co-workers use CBr₄ as a metal-free catalyst for regioselective synthesis of #dihydrochromenoindole fused heterocycles. Scalable, reproducible & bioactive, streamlined synthesis with minimal side reactions🔬
👉 buff.ly/2JUiwKe
👉 buff.ly/2JUiwKe
Unlocking #indane & #indene chemistry! Arun K. Ghosh & Tristan J. McDonald showcase a TiCl₄-mediated intramolecular #Friedel–Crafts cyclization: α-ketoesters give indanyl α-hydroxy esters, elimination to indenes, and even dimeric indanyl-indane derivatives.
👉 buff.ly/FL6d32Q
👉 buff.ly/FL6d32Q
January 7, 2026 at 8:01 AM
Unlocking #indane & #indene chemistry! Arun K. Ghosh & Tristan J. McDonald showcase a TiCl₄-mediated intramolecular #Friedel–Crafts cyclization: α-ketoesters give indanyl α-hydroxy esters, elimination to indenes, and even dimeric indanyl-indane derivatives.
👉 buff.ly/FL6d32Q
👉 buff.ly/FL6d32Q
Advancing #phosphole chemistry✨ Shibo Xu & Koji Hirano report regioselective C−H functionalizations of #benzophospholes via Pd-catalysis & visible-light photochemistry. Modular syntheses lead to diverse donor−acceptor frameworks & unique optoelectronic properties🔬
👉 buff.ly/Am8TwHn
👉 buff.ly/Am8TwHn
January 5, 2026 at 8:00 AM
Advancing #phosphole chemistry✨ Shibo Xu & Koji Hirano report regioselective C−H functionalizations of #benzophospholes via Pd-catalysis & visible-light photochemistry. Modular syntheses lead to diverse donor−acceptor frameworks & unique optoelectronic properties🔬
👉 buff.ly/Am8TwHn
👉 buff.ly/Am8TwHn
🏆 TOP 5 Most Downloaded Articles of 2025!
Luminescent cyclometalated metal complexes represent a versatile platform for advanced sensors and switches⚡️ Poonam Kaswan & co-workers highlight how their behaviors & photophysical properties make them ideal for optoelectronics
👉 buff.ly/dLBJt6q
Luminescent cyclometalated metal complexes represent a versatile platform for advanced sensors and switches⚡️ Poonam Kaswan & co-workers highlight how their behaviors & photophysical properties make them ideal for optoelectronics
👉 buff.ly/dLBJt6q
January 2, 2026 at 8:00 AM
🏆 TOP 5 Most Downloaded Articles of 2025!
Luminescent cyclometalated metal complexes represent a versatile platform for advanced sensors and switches⚡️ Poonam Kaswan & co-workers highlight how their behaviors & photophysical properties make them ideal for optoelectronics
👉 buff.ly/dLBJt6q
Luminescent cyclometalated metal complexes represent a versatile platform for advanced sensors and switches⚡️ Poonam Kaswan & co-workers highlight how their behaviors & photophysical properties make them ideal for optoelectronics
👉 buff.ly/dLBJt6q
🏆 TOP 5 Most Downloaded Articles of 2025!
In this Perspective, Cunningham highlights how combining #Supramolecular chemistry with enantioselective catalysis offers unique advantages over conventional chiral catalysts, while discussing challenges to broader adoption⚗️
👉 buff.ly/j3DmMhE
In this Perspective, Cunningham highlights how combining #Supramolecular chemistry with enantioselective catalysis offers unique advantages over conventional chiral catalysts, while discussing challenges to broader adoption⚗️
👉 buff.ly/j3DmMhE
January 1, 2026 at 9:01 AM
🏆 TOP 5 Most Downloaded Articles of 2025!
In this Perspective, Cunningham highlights how combining #Supramolecular chemistry with enantioselective catalysis offers unique advantages over conventional chiral catalysts, while discussing challenges to broader adoption⚗️
👉 buff.ly/j3DmMhE
In this Perspective, Cunningham highlights how combining #Supramolecular chemistry with enantioselective catalysis offers unique advantages over conventional chiral catalysts, while discussing challenges to broader adoption⚗️
👉 buff.ly/j3DmMhE
🎉 Hello 2026! 🎉
The SYNLETT team is ready for a year of curiosity, creativity, and chemistry magic! Wishing you a bright and joyful year ahead🥳🔬
The SYNLETT team is ready for a year of curiosity, creativity, and chemistry magic! Wishing you a bright and joyful year ahead🥳🔬
January 1, 2026 at 8:01 AM
🎉 Hello 2026! 🎉
The SYNLETT team is ready for a year of curiosity, creativity, and chemistry magic! Wishing you a bright and joyful year ahead🥳🔬
The SYNLETT team is ready for a year of curiosity, creativity, and chemistry magic! Wishing you a bright and joyful year ahead🥳🔬
🏆 TOP 5 Most Downloaded Articles of 2025!
Over the last 25 years, 11 #FDA approved NMEs with a quinoline core treat anemia, malaria, hepatitis & cancer💊 Our perspective by Rav, Sharma & co-workers summarizes their industrial synthesis & clinical applications!
👉 buff.ly/V8d3D3Q
Over the last 25 years, 11 #FDA approved NMEs with a quinoline core treat anemia, malaria, hepatitis & cancer💊 Our perspective by Rav, Sharma & co-workers summarizes their industrial synthesis & clinical applications!
👉 buff.ly/V8d3D3Q
December 31, 2025 at 8:01 AM
🏆 TOP 5 Most Downloaded Articles of 2025!
Over the last 25 years, 11 #FDA approved NMEs with a quinoline core treat anemia, malaria, hepatitis & cancer💊 Our perspective by Rav, Sharma & co-workers summarizes their industrial synthesis & clinical applications!
👉 buff.ly/V8d3D3Q
Over the last 25 years, 11 #FDA approved NMEs with a quinoline core treat anemia, malaria, hepatitis & cancer💊 Our perspective by Rav, Sharma & co-workers summarizes their industrial synthesis & clinical applications!
👉 buff.ly/V8d3D3Q
🏆 TOP 5 Most Downloaded Articles of 2025!
Ma, Li & co-workers report a cost-effective synthesis of #sulfonimidamides from readily available sulfonyl chlorides, delivering these motifs in good yields via sulfinamide and sulfonimidoyl chloride intermediates 🧪
👉 buff.ly/PyjhbHN
Ma, Li & co-workers report a cost-effective synthesis of #sulfonimidamides from readily available sulfonyl chlorides, delivering these motifs in good yields via sulfinamide and sulfonimidoyl chloride intermediates 🧪
👉 buff.ly/PyjhbHN
December 30, 2025 at 8:00 AM
🏆 TOP 5 Most Downloaded Articles of 2025!
Ma, Li & co-workers report a cost-effective synthesis of #sulfonimidamides from readily available sulfonyl chlorides, delivering these motifs in good yields via sulfinamide and sulfonimidoyl chloride intermediates 🧪
👉 buff.ly/PyjhbHN
Ma, Li & co-workers report a cost-effective synthesis of #sulfonimidamides from readily available sulfonyl chlorides, delivering these motifs in good yields via sulfinamide and sulfonimidoyl chloride intermediates 🧪
👉 buff.ly/PyjhbHN
🏆 TOP 5 Most Downloaded Articles of 2025!
A practical, scalable synthesis of the #NaturalProduct (±)-tylophorine🧪 Masal & Reddy report a protecting-group-free route from readily accessible starting materials featuring key cyclization & Clemmensen steps.
#TotalSynthesis
👉 buff.ly/BcrAXq8
A practical, scalable synthesis of the #NaturalProduct (±)-tylophorine🧪 Masal & Reddy report a protecting-group-free route from readily accessible starting materials featuring key cyclization & Clemmensen steps.
#TotalSynthesis
👉 buff.ly/BcrAXq8
December 29, 2025 at 8:00 AM
🏆 TOP 5 Most Downloaded Articles of 2025!
A practical, scalable synthesis of the #NaturalProduct (±)-tylophorine🧪 Masal & Reddy report a protecting-group-free route from readily accessible starting materials featuring key cyclization & Clemmensen steps.
#TotalSynthesis
👉 buff.ly/BcrAXq8
A practical, scalable synthesis of the #NaturalProduct (±)-tylophorine🧪 Masal & Reddy report a protecting-group-free route from readily accessible starting materials featuring key cyclization & Clemmensen steps.
#TotalSynthesis
👉 buff.ly/BcrAXq8