Suzanne Cloonan Lab
@suzcloo.bsky.social
Lab of Dr Suzanne Cloonan at Trinity College Dublin, Ireland 🇮🇪
Adjunct at Weill Cornell Medicine, NYC 🇺🇸
We study #Iron and #Mitochondria in chronic and acute lung 🫁 disease focusing on macrophages, AT2 epithelial cells and host-pathogen interactions
Adjunct at Weill Cornell Medicine, NYC 🇺🇸
We study #Iron and #Mitochondria in chronic and acute lung 🫁 disease focusing on macrophages, AT2 epithelial cells and host-pathogen interactions
Pinned
Suzanne Cloonan Lab
@suzcloo.bsky.social
· Mar 19
Are you a basic researcher exploring COPD disease mechanisms, a translational scientist developing new COPD therapies, or a clinician seeking to improve patient outcomes, join myself and @mareikelehmann.bsky.social in Prague Nov 6-7 2025 for an ERS Research Seminar in collaboration with COPDiNet.
Reposted by Suzanne Cloonan Lab
At #Bioiron impromptu dinner with 26 people at a wonder Persian Restaurant in Montreal with @hosseinardehali.bsky.social @suzcloo.bsky.social @manciaslab.bsky.social @ironresearchlab.bsky.social
May 28, 2025 at 1:56 AM
At #Bioiron impromptu dinner with 26 people at a wonder Persian Restaurant in Montreal with @hosseinardehali.bsky.social @suzcloo.bsky.social @manciaslab.bsky.social @ironresearchlab.bsky.social
Congratulations to Dr @lynnefaherty.bsky.social on the successful defense of her Thesis last Friday! Can’t wait to see what you do next Dr Faherty!
May 5, 2025 at 1:16 PM
Congratulations to Dr @lynnefaherty.bsky.social on the successful defense of her Thesis last Friday! Can’t wait to see what you do next Dr Faherty!
Reposted by Suzanne Cloonan Lab
#WeekendRead! #EveryCellIsAnImmuneCell! Peng Bai Marichal &co show @ Science Immunology that endothelial cells produce TGFb to differentiate monocytes into #lung interstitial macrophages preventing aging & fibrosis
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Endothelial-driven TGFβ signaling supports lung interstitial macrophage development from monocytes
Endothelial Tgfβ1 shapes the development and functional identity of lung interstitial macrophages.
www.science.org
April 27, 2025 at 2:59 PM
#WeekendRead! #EveryCellIsAnImmuneCell! Peng Bai Marichal &co show @ Science Immunology that endothelial cells produce TGFb to differentiate monocytes into #lung interstitial macrophages preventing aging & fibrosis
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Suzanne Cloonan Lab
Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes @cp-cellreports.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
April 17, 2025 at 6:01 PM
Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes @cp-cellreports.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Suzanne Cloonan Lab
Very productive visit from ERC President Maria Leptin - on the same page as our Taoiseach and Minister for Science when it comes to the need for increased funding for science in Ireland and Europe and ERC independence
Back in Dublin - and what a warm welcome!
Valuable in-depth conversation with @micheal-martin.bsky.social. Thanks Taoiseach for your support!
Also much enjoyed meeting minister @LawlessJ. Glad to see we have shared priorities.
And huge thanks to Luke O’Neill!
Valuable in-depth conversation with @micheal-martin.bsky.social. Thanks Taoiseach for your support!
Also much enjoyed meeting minister @LawlessJ. Glad to see we have shared priorities.
And huge thanks to Luke O’Neill!
April 2, 2025 at 8:09 AM
Very productive visit from ERC President Maria Leptin - on the same page as our Taoiseach and Minister for Science when it comes to the need for increased funding for science in Ireland and Europe and ERC independence
Reposted by Suzanne Cloonan Lab
Iron absorption, storage and conservation in the body
"Screening, diagnosis, and treatment of adults with absolute iron deficiency without anemia and iron-deficiency anemia."
jamanetwork.com/journals/jam...
"Screening, diagnosis, and treatment of adults with absolute iron deficiency without anemia and iron-deficiency anemia."
jamanetwork.com/journals/jam...
March 31, 2025 at 12:23 AM
Iron absorption, storage and conservation in the body
"Screening, diagnosis, and treatment of adults with absolute iron deficiency without anemia and iron-deficiency anemia."
jamanetwork.com/journals/jam...
"Screening, diagnosis, and treatment of adults with absolute iron deficiency without anemia and iron-deficiency anemia."
jamanetwork.com/journals/jam...
Congrats Rafii Lab @weillcornell.bsky.social ! Fli-1, a transcription factor that coordinates the two-way relationship between hematopoietic stem cells & angiocrine factors supplied by the vascular niche: a new paradigm in the physiology of hematopoiesis?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing - Nature Immunology
Itkin et al. identify a role for Fli-1 in hematopoietic stem cell activation during regenerative hematopoiesis. They show that Fli-1 coordinates hematopoietic stem cells to stimulate niche-derived Not...
www.nature.com
March 25, 2025 at 1:55 PM
Congrats Rafii Lab @weillcornell.bsky.social ! Fli-1, a transcription factor that coordinates the two-way relationship between hematopoietic stem cells & angiocrine factors supplied by the vascular niche: a new paradigm in the physiology of hematopoiesis?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Suzanne Cloonan Lab
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.
Learn more in this week's issue: scim.ag/3FA3Ygq
Learn more in this week's issue: scim.ag/3FA3Ygq
March 20, 2025 at 6:05 PM
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.
Learn more in this week's issue: scim.ag/3FA3Ygq
Learn more in this week's issue: scim.ag/3FA3Ygq
Are you a basic researcher exploring COPD disease mechanisms, a translational scientist developing new COPD therapies, or a clinician seeking to improve patient outcomes, join myself and @mareikelehmann.bsky.social in Prague Nov 6-7 2025 for an ERS Research Seminar in collaboration with COPDiNet.
March 19, 2025 at 12:42 PM
Are you a basic researcher exploring COPD disease mechanisms, a translational scientist developing new COPD therapies, or a clinician seeking to improve patient outcomes, join myself and @mareikelehmann.bsky.social in Prague Nov 6-7 2025 for an ERS Research Seminar in collaboration with COPDiNet.
Heterogeneous human AM subsets have counterparts in mice! Nice work from @claudjak.bsky.social lab
The Heterogeneity, Parallels, and Divergence of Alveolar Macrophages in Humans and Mice
This study reveals complex heterogeneity in mouse AMs, highlighting conserved and unique subsets across humans and mouse
@xinli0419.bsky.social
@claudjak.bsky.social
#macrophages
🔗 tinyurl.com/yb66ch6e
This study reveals complex heterogeneity in mouse AMs, highlighting conserved and unique subsets across humans and mouse
@xinli0419.bsky.social
@claudjak.bsky.social
#macrophages
🔗 tinyurl.com/yb66ch6e
March 18, 2025 at 1:06 PM
Heterogeneous human AM subsets have counterparts in mice! Nice work from @claudjak.bsky.social lab
One of my favorite topics right now! Very nice review on The evolutionary tug-of-war of macrophage metabolism during bacterial infection from @timsparwasser.bsky.social
read here 👇
www.sciencedirect.com/science/arti...
read here 👇
www.sciencedirect.com/science/arti...
The evolutionary tug-of-war of macrophage metabolism during bacterial infection
The function and phenotype of macrophages are intimately linked with pathogen detection. On sensing pathogen-derived signals and molecules, macrophage…
www.sciencedirect.com
March 18, 2025 at 12:46 PM
One of my favorite topics right now! Very nice review on The evolutionary tug-of-war of macrophage metabolism during bacterial infection from @timsparwasser.bsky.social
read here 👇
www.sciencedirect.com/science/arti...
read here 👇
www.sciencedirect.com/science/arti...
Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae | Science www.science.org/doi/10.1126/...
Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae
Peroxisomes are vital but often overlooked metabolic organelles. We found that excessive interferon signaling remodeled macrophage peroxisomes. This loss of peroxisomes impaired inflammation resolutio...
www.science.org
March 12, 2025 at 9:58 AM
Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae | Science www.science.org/doi/10.1126/...