Researchers find DMT – used in shamanic rituals – in tandem with psychotherapy has significant effect People with major depressive disorder can see a rapid and lasting improvement after a single dose of the psychedelic drug dimethyltryptamine (DMT) when it is combined with psychotherapy, doctors have said. A small clinical trial involving 34 people found that psychedelic-assisted therapy prompted a swift reduction in depressive symptoms that endured long after the drug had worn off, with some still feeling the benefits six months later. Continue reading...

Growing up in a turbulent household taught me to expect the worst. Then one day I found £20 in the street and shifted my thinking Growing up, I was envious of one type of person. It was never the kids who were smarter, sportier or more popular. My awe was reserved for a rarer breed of people: optimists. I was hypersensitive to the ease with which they sailed through exams, social gatherings or teenage milestones with a sunny conviction that things would more or less work out. To me, they were the chosen people. “It’ll be fine,” one such friend would reassure me. “Or you could embarrass yourself,” my mind would purr like a villain. “Be rejected. Fail.” I was a chronic worrier. A negative Nancy. I couldn’t fathom that people’s brains weren’t hardwired to compulsively fear things might go wrong. I grew up as the eldest daughter in a turbulent household where my father’s moods would plummet quickly and I walked on a knife-edge. Every morning, the second my eyes opened, I would force myself to accept it was going to be a bad day – an act of self-preservation so the rug could never get pulled from under my feet hoping for better. My thinking was that if you always expected the worst, things had a tendency to turn out better than you imagined. Continue reading...

Leanne and Luke have been together for many years, navigating their own experiences of mental health problems. In this video, they discuss how you can talk to your partner about your mental health. You can watch the full interview with Leanne and Luke over on our YouTube channel. You can learn more about looking after your mental wellbeing on Mind’s website – mind.org.uk This film was created as part of our Community Reporters programme, a project funded by YouTube Health to train people with lived experience to create their own content. For mental health information and signposting call Mind on 0300 123 3393 - Weekdays, 9am - 6pm For someone to talk to about how you’re feeling: 📱 Text Shout on 85258 - https://giveusashout.org 📞 Call Samaritans on 116 123 - anytime - https://www.samaritans.org/ 📞 Call Calm 0800 58 58 58 - 5pm to midnight - https://www.thecalmzone.net/ 👉 Visit OCD Action https://ocdaction.org.uk/

Your trusted guide to the top independent news and views of the day...

He didn’t look like a stereotypical ‘drug addict’, but when he fled to South Africa with all our savings it was obvious that is what he had become When I tell people that a drug addiction nearly killed my dad, I know what most of them are thinking. Heroin. Crack. Maybe meth or ket. Those substances that steal your soul and slowly wreak havoc on your body. They’re imagining Trainspotting; too-skinny frames and protruding hip bones, the physical effects of addiction that are impossible to miss. But that isn’t how it played out in my family. Continue reading...

Struggling with Lexapro not giving the results you expected? You’re not alone. In this video, we explore common reasons why Lexapro might not work for some people, including dosage issues, timing, individual body chemistry, and underlying conditions. Understanding these factors can help you have a more informed discussion with your doctor and explore alternative treatment options. Watch to learn why your medication might not be effective and what steps you can take next. Lexapro Didn't Work? Here's Why #shorts Lexapro promised anxiety relief, but delivered...nothing? Many experiences nausea, brain fog, & emotional flatness. If your world shrinks, it's not working. 😍 𝐈 𝐇𝐎𝐏𝐄 𝐘𝐎𝐔 𝐆𝐔𝐘𝐒 𝐄𝐍𝐉𝐎𝐘 𝐓𝐇𝐈𝐒! ▶️ If you enjoy this video, please like it and share it. ▶️ Don't forget to subscribe to this channel for more updates. 👉𝑷𝒍𝒆𝒂𝒔𝒆 𝒔𝒉𝒂𝒓𝒆 𝒘𝒊𝒕𝒉 𝒚𝒐𝒖𝒓 𝒇𝒓𝒊𝒆𝒏𝒅𝒔 𝒂𝒏𝒅 𝒇𝒂𝒎𝒊𝒍𝒚. 𝑨𝒍𝒔𝒐 𝒅𝒐𝒏'𝒕 𝒇𝒐𝒓𝒈𝒆𝒕 𝒕𝒐 𝒍𝒊𝒌𝒆, 𝒔𝒖𝒃𝒔𝒄𝒓𝒊𝒃𝒆, 𝒂𝒏𝒅 𝒉𝒊𝒕 𝒕𝒉𝒆 𝒏𝒐𝒕𝒊𝒇𝒊𝒄𝒂𝒕𝒊𝒐𝒏 𝒃𝒆𝒍𝒍 𝒕𝒐 𝒏𝒐𝒕𝒊𝒇𝒚 𝒚𝒐𝒖 𝒊𝒇 𝑰 𝒑𝒐𝒔𝒕 𝒂 𝒏𝒆𝒘 𝒗𝒊𝒅𝒆𝒐. 💊𝐇𝐀𝐒𝐇𝐓𝐀𝐆𝐒: #lexapro#antidepressants#mentalhealth#depressionhelp#anxietyrelief#medicationtips #mentalwellness#mentalhealthawareness#antidepressanttips#anxietyhelp#mentalhealthsupport #depressiontreatment#mentalhealthmatters#anxietytreatment#medicationawareness #mentalhealthjourney#depressionrecovery#anxietymanagement#mentalhealthtips #mentalhealthguide

The long-running series in which readers answer other readers’ questions ponders how to overcome fear and do what is needed This week’s question: what would be the most socially useful way to spend a billion dollars? Is it possible to acquire courage if you don’t have it? I was moved by the recent story of the Australian boy who swam to land for several hours in rough waters to raise the alarm that his mother and siblings had been swept out to sea. Despite his exhaustion, he then ran several kilometres to find a phone. But I’m also thinking of the lesser demands for courage – such as standing up to a friend, or family member, or tackling a company that’s ignoring your polite requests when you’re suffering from its actions. Or I also wonder how people do certain jobs that, to me, require buckets of courage: starting a business or any other sort of professional risk-taking; reporting from a war zone like Lyse Doucet or Jeremy Bowen. Or just being a police officer knocking on the door of a suspect and not knowing what is on the other side. Continue reading...

After her death, police dropped a case examining Katie Madden’s former partner, despite evidence he had repeatedly told her to kill herself * Revealed: The true toll of female suicides in UK with domestic abuse at their core Hours before Katie Madden took her own life, she had a tense phone call with her former partner Jonathon Russell. Russell was on bail after allegedly assaulting Madden – he was banned from contacting her – but the conversation took place nevertheless. There was a witness to the call who gave evidence to the inquest into Madden’s death. Mason Jones, a friend of Madden’s, said Russell was “vile” and “abusive”. Although Jones said he could not remember the exact words Russell used, he said: “I recall Jon saying at least once that he was in control of the town and would end her life if she didn’t do it herself.” Continue reading...

Send us a text (https://www.buzzsprout.com/twilio/text_messages/1149857/open_sms) It's no secret that stretching our comfort zone to include more situations is a good idea. But it's called a comfort zone for a reason isnt it? It's comfortable there. So if life is comfortable and the alternative is uncomfortable then we're not going to have a great deal of motivation to make a change. But do we even need to? And if so, how? Support the show (https://patreon.com/richardnicholls) Join the Patreon community https://www.patreon.com/richardnicholls Social Media Links Bluesky https://bsky.app/profile/richardnicholls.net Threads https://www.threads.net/@richardnichollsreal Instagram https://www.instagram.com/richardnichollsreal Facebook https://www.facebook.com/RichardNichollsAuthor Youtube https://www.youtube.com/richardnicholls TikTok https://www.tiktok.com/@richardnichollsauthor X https://x.com/richardnicholls (https://twitter.com/richardnicholls)

I am furious that women and children have to endure a crisis like this for progress to become politically possible. But I will seize this moment * Jess Phillips MP is parliamentary under-secretary of state for safeguarding and violence against women and girls * Jess Phillips calls for Epstein files to be catalyst for long-term legislative change It always takes a calamity – a dreadful murder that reaches every front page, a mass paedophile ring being uncovered, or a political scandal unfolding – to make institutions sit up and act on violence against women and children. These windows of potential energy are never wasted by women’s rights activists. Historically, they have used them to build the #MeToo movement, to fight for legislation change and to push for greater resources for victims. I’ve done it, many times – “never waste a crisis” is my mantra. In the past few weeks, while the nation’s attention has been on the political fallout from the Epstein files, I have seen the opportunity to push for more, for better. To move beyond the throwaway line about the victims being the most important thing – and to actually make them just that. Deeds not words are what matter. If repentance and sorrow is all we achieve out of the courage of the Epstein victims, we will have failed; change is all that will suffice. Jess Phillips is MP for Birmingham Yardley and parliamentary under-secretary of state for safeguarding and violence against women and girls Do you have an opinion on the issues raised in this article? If you would like to submit a response of up to 300 words by email to be considered for publication in our letters section, please click here. Continue reading...

Since its debut in 2013, Better Than Yesterday has become one of Australia’s most recognised and enduring podcasts, consistently delivering insightful content that resonates with listeners across the country. Hosted by best-selling author and popular TV presenter Osher Günsberg, each week the Better Than Yesterday podcast brings listeners and viewers useful tools and conversations to help make your day today a little better than yesterday. With a focus on personal development and mental fitness, Osher is joined every week by some of the biggest names and biggest brains on the planet, for a podcast that inspires listeners to embrace challenges and remember to laugh while moving toward a life of value. Now you can watch a carefully curated collection of Osher's best episodes in the 24/7 livestream channel. For brand new content every week, be sure to subscribe to the channel or your preferred podcast platform. You can also explore hundreds of past episodes! More from Osher: 🎙 Better Than Yesterday podcast: https://tinyurl.com/BTYpodcast 📬 Sign up to the Better Than Yesterday newsletter: https://makeitbetterthanyesterday.kit.com/7d9d18dcee 📸 Instagram: https://www.instagram.com/osher_gunsberg 📖 Books: https://linktr.ee/osher_gunsberg 📺 Story Club on YouTube: https://www.youtube.com/@storyclublive 🎟️ Story Club tickets: https://linktr.ee/osher_gunsberg

This video explains centanafadine, a new non-stimulant ADHD medication that targets norepinephrine, dopamine, and serotonin — and why that third pathway may matter for real-world ADHD. In this episode, Dr Sanil Rege explores why ADHD may be better understood as a disorder of regulation — not just attention — and how centanafadine’s triple reuptake inhibition (ND-SRI) mechanism attempts to address attention, impulse control, emotional reactivity, and sleep instability. Centanafadine is currently under FDA priority review and is not yet approved. This is an educational discussion based on current trial data. ⏱️ Chapters 00:00 – Introduction to Centanafadine and Its Relevance to ADHD 02:05 – What Is Centanafadine? (ND-SRI Mechanism Explained Simply) 03:29 – The Relevance of Serotonin in ADHD management 05:50 – What Do Centanafadine Clinical Trials Show - The Evidence Base 06:41 – Side Effects & Tolerability Profile of Centanafadine? 07:49 – Who Might Centanafadine Suit? ADHD Phenotypes & Clinical Scenarios 🧠 What You’ll Learn For Clinicians: • What a triple reuptake inhibitor (ND-SRI) means in practice • How serotonin modulates dopaminergic and noradrenergic circuits • The concept of ADHD as a dysregulation phenotype • How Centanafadine compares to stimulants and other non-stimulants • Tolerability profile and misuse considerations • Where this medication may fit in real-world prescribing For Patients & Science-Curious Viewers: • Why ADHD is more than “can’t concentrate” • How dopamine, norepinephrine, and serotonin interact • Why emotional reactivity and sleep instability matter • What to realistically expect from new medications • Why no medication is a “magic pill” Dr Sanil Rege is a Consultant Psychiatrist (MBBS, MRCPsych, FRANZCP) and educator who has treated thousands of patients with ADHD. If you’re a clinician wanting deeper ADHD training explore The Academy by Psych Scene: 👉 https://academy.psychscene.com/ Watch the full ADHD playlist here: 👉 ADHD Playlist : https://youtube.com/playlist?list=PLV0KZkVDyoOEOaE9DoJgpXzCXi_0b4sZz&si=qeae_JcxvJVwUh1M This video is for educational purposes only and does not constitute personalised medical advice. #ADHD #Centanafadine #NonStimulant #Psychiatry #Neuroscience #Dopamine #Serotonin #Norepinephrine #ADHDTreatment #MentalHealth #ExecutiveFunction #DrRege 🎓RESOURCES BY PSYCH SCENE: 🌐The Academy by Psych Scene: PSYCHIATRY EDUCATION REDEFINED https://academy.psychscene.com/ Revolutionary psychiatry learning. 🌐Psych Scene Hub: PSYCHIATRY TEXTBOOK OF THE FUTURE https://psychscenehub.com/ The Hub is dedicated to helping you become a better mental health professional. Our team of academic and clinical experts bring you powerful summaries, videos and interviews in psychiatry and neurosciences. 🌐Psych Interview Online: REAL WORLD SKILLS FOR REAL WORLD SUCCESS https://www.psychinterview.com/ The Psych Interview online courses offer high-quality training to help you improve your psychiatric interview skills through self-study. 🌐Psych Scene Online: THE ONLINE COURSES TO HELP YOU SUCCEED https://ranzcpexams.psychscene.com/ Learn at your own pace with the RANZCP Written Exam prep online courses. 🌐Psych Scene: THE PSYCHIATRY TRAINING EXPERTS https://psychscene.com/ Psych Scene offers specialised training and professional development for Psychiatry Trainees, Psychiatrists, General Practitioners and Mental Health Practitioners. -- 📱SOCIALS Subscribe for weekly videos on Psychiatry and Neuroscience: Facebook: https://m.facebook.com/PsychSceneHub Instagram: https://www.instagram.com/psychiatry.excellence/ – 👋 LET’S CONNECT! Follow Sanil Rege on LinkedIn: https://www.linkedin.com/in/sanilrege

Trans children have rights under international and domestic law, and we can be more assertive both in calling attention to rights violations, and in demanding institutions uphold these rights in policy and practice. This accountability should be more robust in Scotland, who in 2024 brought the UN Convention on the Rights of the Child (UNCRC) … Continue reading Upholding trans children’s rights

The historical blame on mothers for autism and ADHD stems from misconceptions linking maternal behavior to child behavior, now debunked. Current science confirms ADHD's heritability, emphasizing the importance of valid diagnosis and treatment over outdated maternal blame.

It’s record day in a town somewhat nearby! Yay! Right now all I have is a suitcase record player, so it’s not great, but my stepdad isn’t really using the turntable he brought up from the basement so I think I’m going to kidnap that and relocate it to my bedroom. Ha! It needs like … Continue reading So excited!

Neil Saunders of the Premier League responds to a letter about ongoing help for academy footballers who have been released from their contracts The Premier League introduced the elite player performance plan (EPPP) in 2012 to modernise and professionalise youth development in English football. Since then, the education, care and support provided to young players, both within academies and beyond, has evolved significantly (Letters, 7 January). The Premier League, clubs and selected partners work collaboratively to support players from under-nine level through to the first team, with a strong focus on mental health and wellbeing. Continue reading...

Our world is not set up to honour the bond between pet and human, but we can reduce expectations of ourselves as we grieve * The modern mind is a column where experts discuss mental health issues they are seeing in their work Last week, I sat in the emergency department of a veterinary hospital for hours with my 12-year-old greyhound, Karla. She’d woken screaming in severe pain, so we went to the emergency department after consulting a home visiting veterinarian. The vet recommended we admit Karla for X-rays to see if the pain was caused by osteosarcoma – a common and deadly cancerexperienced by greyhounds. As we waited, I saw a weeping family, their golden retriever lying preternaturally still on a bed in a consulting room. Their sobs were guttural; I knew what had happened. I looked at social media to distract myself and saw a post from Nagi, talking about her beloved dog Dozer’s illness, and felt a sense of connection, but also devastatingly alone in the bond between my dog and me, and the decisions I would need to make about her. Continue reading...

Does it only affect weak people? Is work always the cause? Burnout myths, busted by the experts Once, after surviving yet another round of redundancies in a former job, I did something very odd. I turned off the lights in my room and lay face-down on the bed, unable to move. Rather than feeling relief at having escaped the axe, I was exhausted and numb. I’m not the only one. Fatigue, apathy and hopelessness are all textbook signs of burnout, a bleak phenomenon that has come to define many of our working lives. In 2025, a report from Moodle found that 66% of US workers had experienced some kind of burnout, while a Mental Health UK survey found that one in three adults came under high levels of pressure or stress in the previous year. Despite the prevalence of burnout, plenty of misconceptions around it persist. “Everybody thinks it’s some sort of disease or medical condition,” says Christina Maslach, the psychology professor who was the first to study the syndrome in the 1970s. “But it’s actually a response to chronic job stressors – a stress response.” Here we separate the facts from the myths. Continue reading...

In this episode, I sit down with Blimie Heller of Unconditional Parenting to explore how respectful parenting is a powerful form of child sexual abuse prevention. Prevention doesn’t start with stranger danger. It starts at home, in everyday moments of connection, boundaries, and respect. If you care about raising confident, protected kids, this conversation is for you. Trigger Warning: This episode contains discussion of child sexual abuse and its lasting impact. Listener discretion is strongly advised. Recommended Resources: Sacred Not Secret Course https://elishevaliss.com Unconditional Parenting www.blimieheller.com Support and Helplines: RAINN, www.rainn.org 1-800-656-HOPE 1in6, www.1in6.org Darkness to Light, www.d2l.org Survivors of Incest Anonymous, www.siawso.org Zaakah, www.zaakah.org Sacred Spaces, www.jewishsacredspaces.org JCASA, jcasavictims.org Survivors for Justice, survivorsforjustice.org You are not alone. Healing is possible. The views and opinions expressed by guests on the Silent No More podcast are their own and do not necessarily represent the views of Better Safe Than Silent.

Self-reliance is often encouraged over asking others for help in the modern world. But doing everything yourself can be a sign that you are scared of intimacy When a relative was seriously ill and in intensive care for more than a month, Cianne Jones stepped in. “I took it upon myself to be that person in the hospital every single day – chasing doctors, taking notes, making sure I understood why they were doing things.” It was so stressful, she says, that at one point her hair started falling out, but she ploughed on. It was Jones’s therapist who gently questioned whether she was going to ask for help. Jones laughs. “The hair falling out didn’t suggest to me that I needed help, it was somebody else looking in and saying that.” She has a large, close family who would have helped immediately – and did, once Jones asked – it’s just that it didn’t occur to her to ask. “I had taken that role on: ‘I’m just going to get everything done.’ I just took off, and that was it.” Continue reading...

It’s been an interesting couple of weeks or so. I was in the hospital for a week with pancreatitis and then out for four days, and then had to call an ambulance because I got hit with a wall of pain so bad I couldn’t stand. That was another three days. Thankfully, I got out … Continue reading Wee-ooo!

Or: What happens when you exercise democratic rights in Tim Wilson's Goldstein