Shourya Roy Burman
@ssroyburman.bsky.social
Scientist @danafarber.bsky.social @harvardmed.bsky.social | Biomolecular engineer | Targeted protein degradation | Degron tags | Views are my own
For the first TPD webinar of 2025, we’re thrilled to host Dennis Hu from Drug Hunter! Join us to learn about industry highlights in targeted protein degradation & induced proximity and how these therapies are reshaping drug discovery. 🧪
🗓️ Jan 9 | 🕛 12 PM EST | Open to all, register at bit.ly/40hsLxE
🗓️ Jan 9 | 🕛 12 PM EST | Open to all, register at bit.ly/40hsLxE
January 3, 2025 at 10:56 PM
For the first TPD webinar of 2025, we’re thrilled to host Dennis Hu from Drug Hunter! Join us to learn about industry highlights in targeted protein degradation & induced proximity and how these therapies are reshaping drug discovery. 🧪
🗓️ Jan 9 | 🕛 12 PM EST | Open to all, register at bit.ly/40hsLxE
🗓️ Jan 9 | 🕛 12 PM EST | Open to all, register at bit.ly/40hsLxE
Through a series of cryo-EM structures, this study shows how an E2 and ubiquitin itself can play a "structural" role to specify ubiquitin linkage. 🧪
Lovely work by Katrina Warner, @moritzhunkeler.bsky.social @kheewoongbaek.bsky.social, @katherinedonovan.bsky.social and others in the Fischer Lab!
Lovely work by Katrina Warner, @moritzhunkeler.bsky.social @kheewoongbaek.bsky.social, @katherinedonovan.bsky.social and others in the Fischer Lab!
New #preprint - a amazing study of HECT ligase Tom1. This paper is a treat for those of you who LOVE #cryoEM and for those who love #ubiquitin! Congrats to the Fischer lab, including @moritzhunkeler.bsky.social and @ssroyburman.bsky.social who are on #bluesky.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Structural ubiquitin contributes to K48 linkage-specificity of the HECT ligase Tom1
Homologous to E6AP C-Terminus (HECT) ubiquitin ligases play key roles in essential pathways such as DNA repair, cell cycle control or protein quality control. Tom1 is one of five HECT ubiquitin E3 lig...
www.biorxiv.org
November 27, 2024 at 7:37 PM
Through a series of cryo-EM structures, this study shows how an E2 and ubiquitin itself can play a "structural" role to specify ubiquitin linkage. 🧪
Lovely work by Katrina Warner, @moritzhunkeler.bsky.social @kheewoongbaek.bsky.social, @katherinedonovan.bsky.social and others in the Fischer Lab!
Lovely work by Katrina Warner, @moritzhunkeler.bsky.social @kheewoongbaek.bsky.social, @katherinedonovan.bsky.social and others in the Fischer Lab!